Levocetirizine Dosage

Usual Adult Dose for Allergic Rhinitis

Seasonal and perennial allergic rhinitis and chronic idiopathic urticaria;
5 mg orally once daily in the evening

Usual Adult Dose for Urticaria

Seasonal and perennial allergic rhinitis and chronic idiopathic urticaria;
5 mg orally once daily in the evening

Usual Pediatric Dose for Allergic Rhinitis

Seasonal allergic rhinitis:
12 years or older: 5 mg orally once daily in the evening
6 to 11 years old: 2.5 mg orally once daily in the evening
2 to 5 years old: 1.25 mg orally once daily in the evening

Perennial allergic rhinitis and chronic idiopathic urticaria:
12 years or older: 5 mg orally once daily in the evening
6 to 11 years old: 2.5 mg orally once daily in the evening
6 months to 5 years old: 1.25 mg orally once daily in the evening

Usual Pediatric Dose for Urticaria

Seasonal allergic rhinitis:
12 years or older: 5 mg orally once daily in the evening
6 to 11 years old: 2.5 mg orally once daily in the evening
2 to 5 years old: 1.25 mg orally once daily in the evening

Perennial allergic rhinitis and chronic idiopathic urticaria:
12 years or older: 5 mg orally once daily in the evening
6 to 11 years old: 2.5 mg orally once daily in the evening
6 months to 5 years old: 1.25 mg orally once daily in the evening

Renal Dose Adjustments

Contraindicated in end stage renal disease, patients undergoing hemodialysis, and patients with CrCl less than 10 mL/min. Contraindicated in children less than 12 years old with renal impairment.

Adults and children 12 years and older:
CrCl 50 to 80 mL/min: 2.5 mg orally daily
CrCl 30 to 49 mL/min: 2.5 mg orally every other day
CrCl 10 to 29 mL/min: 2.5 mg orally twice weekly (once every 3 to 4 days)

Liver Dose Adjustments

No adjustment recommended

Dialysis

Levocetirizine is contraindicated in patients on dialysis.
Hemodialysis: Levocetirizine is not effectively removed
Peritoneal dialysis: No data available