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User Reviews for Doxepin

Also known as: Adapin, Silenor, Sinequan

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Doxepin.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Irritable Bowel Syndrome 2 reviews 137 medications
   
10
Major Depressive Disorder 1 reviews 46 medications
   
10
Urticaria 9 reviews 184 medications
   
7.4
Depression 12 reviews 78 medications
   
7.4
Anxiety 10 reviews 63 medications
   
7.0
Insomnia 137 reviews 110 medications
   
6.7
Reflex Sympathetic Dystrophy Syndrome 1 reviews 2 medications
   
3.0
Summary of Doxepin reviews 172 reviews 7.4

Reviews for Doxepin

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For Depression: "My sister took doxipen and it had a horrible reaction... anxiety, changed her personality, sleeplesness... she told her Doctor so he increased the dose... she hadn't slept in 3 days so she took xanex to sleep... she died that night... 6/26/2016... she was 28 years old."

   
1.0

Sarah Dooly (taken for 1 to 6 months) July 16, 2016

3 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Insomnia: "Horrible drug. Felt like a zombie for about 14 hours after taking 1/2 a 25mg capsule. Never again."

   
1.0

George Hatfield (taken for less than 1 month) July 11, 2016

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For Insomnia: "My doc prescribed 40 mg at bedtime to shift my sleep cycle. History of acute anxiety attacks w/ tachycardia, and essential tremor. First dose I felt agitated, anxious, and my heart rate went up to 160. It did not help me fall asleep any earlier, next day blurred vision and 'migraine aura'. Things went downhill from there. My doctor said to continue it for at least 4 weeks and the side effects would go away. They did not - things continued to worsen. The tremor increased to where I could not use the computer, headaches got worse, anxiety increased, I became irritable and angry, and my blood sugar went through the roof. After 5 weeks I threw it away - blood sugar still high and tremor still worse after quitting a month ago."

   
1.0

MountainGeek (taken for 1 to 6 months) July 11, 2016

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Silenor (doxepin) for Insomnia: "Doctor recommended I try this after failed medication after failed medication.. So far, it has helped my insomnia drastically!"

   
10

George Shilly July 7, 2016

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Silenor (doxepin) for Insomnia: "I took this to help with my insomnia. I work different hours at the hospital and I haven't been able to overcome the Insomnia on my days off. Silenor has helped me so far, I hope that it stays that way."

   
10

Joseph_Smith June 30, 2016

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For Insomnia: "I've been taking 100mg @ night for insomnia/anxiety for approximately 1 1/2 years! I love it! I take it about 30-45 minutes before bed and BAM I'm out! The only side effects I've noticed is talking in my sleep (nothing major though)!! I would highly recommend this medication for insomnia."

   
10

berrylove (taken for 1 to 2 years) June 29, 2016

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Silenor (doxepin) for Insomnia: "Made me extremely agitated and nervous during the night, very disappointed and actually scared after taking it. Very expensive as well."

   
1.0

notsleep (taken for less than 1 month) June 28, 2016

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Silenor (doxepin) for Insomnia: "First night I tried a half. Fell asleep but woke up and was wide awake through the rest of the night. 2 nd night took a full pill feel heart pounding numb fingers can't fall asleep now wide awake. Worse then first night."

   
1.0

Shan no sleep June 23, 2016

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For Insomnia: "Have taken this medication for 10 nights. Nothing has improved whatsoever. I take as directed 2 hours before bedtime. It has not been the answer to a sleepless night I had hoped for. Still waking up after an hour or hour and half,and keep waking throughout the remainder of the night."

   
1.0

tired beyond description June 19, 2016

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For Insomnia: "Tried 10 mg 3 nights in a row. Stayed awake literally all night. Not helpful for sleep."

   
1.0

Turtle Bear (taken for less than 1 month) June 6, 2016

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For Insomnia: "I took this medicine at 11 p.m., asleep a little after midnight, and woke at 3:20 a.m.. I have been awake since then, it is now 4:18, and I still cannot fall back asleep! The first night I took it, it did the something plus a side of anxiety attacks. Thought I'd give it a try again, but nope, no more of this! Smh!"

   
1.0

Sleepless in Az (taken for less than 1 month) May 27, 2016

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For Insomnia: "I have severe sleep problems and now take 50mg of doxepin nightly. I fall asleep and stay asleep. I have tried numerous other meds and most either don't work or work for only a short period of time, this has not been a problem with doxepin."

   
10

BSFMI (taken for 1 to 6 months) May 27, 2016

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For Irritable Bowel Syndrome: "Had symptoms of IBS D for years, after a bout with a bad colon infection. Following many tests, medication trials that all failed, a great GI specialist suggested doxepin, it was a miracle. Try it, it's cheap, few side effects, and it's effective!"

   
10

PamJo (taken for 2 to 5 years) May 23, 2016

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For Depression: "Took care of my depression, insomnia, and IBS"

   
9.0

Inakldy (taken for 6 months to 1 year) May 22, 2016

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For Insomnia: "Low dose doxepin did not help at all with my insomnia. I tried doses from 5mg to 20mg and it never helped with either falling asleep or staying asleep. Side effects: very dry mouth, sore throat, headache. On the plus side it's very inexpensive and I was able to discontinue it without any withdrawal effects."

   
2.0

StillSleepless (taken for 1 to 6 months) May 13, 2016

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For Insomnia: "Tried this pill last night. Did sleep pretty well but very hungover in the morning. It is just not worth it. Can't function normally today. I was taking Ativan which was great but the doctor will not prescribe it any more. Can't believe that one little pill can make me feel so awful. I will never take it again!!"

   
1.0

Judeler May 10, 2016

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For Urticaria: "I've been taking 10mg for several months now, for chronic itching. It has helped ALOT although it has not gone away my doctor told me it will take time but eventually it will get better. It makes me very drowsy but I've gotten use to it now"

   
6.0

LoveJade May 9, 2016

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Silenor (doxepin) for Insomnia: "I tried the 3 mg dose last night. I slept worse than when I take nothing. I felt so agitated and miserable. Tossed and turned all night. Will not take it again!"

   
1.0

Needshuteye (taken for less than 1 month) May 4, 2016

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Silenor (doxepin) for Insomnia: "Been using it for about 5 months and it has been a miracle worker until recently. A few weeks ago started having random sleepless nights. This week has been terrible waking up after 3-4 hours and feeling wide awake. Not sure if my body is getting used to it but I thought I'd check the reviews to see if anyone else has had the same problem. I hope this is a fluke because Silenor really had changed my life and even though it was expensive it was worth being able to function the next day."

   
8.0

PHick April 21, 2016

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For Insomnia: "Too strong for me; slept for 10+ hours and felt groggy for most of the next day when I took it. Is worth a try if you suffer from severe insomnia- because in that regard, it did work."

   
3.0

Kbird91 April 20, 2016

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For Insomnia: "Have been taking doxepin 10mg for sleep for at least 10 years. When I found this, I felt like I might actually manage life. Have problems staying asleep since onset of menopause and doxepin really helps. Since I am overweight my doctor will only prescribe for me to take every other night as he believes it causes weight gain. We disagree on this subject."

   
9.0

mskrazy April 17, 2016

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For Depression: "Has many years of problems with depression, anxiety , derealization etc. Eventually learned these all related to Complex Multiple Trauma. But that is another story. Doxepin pretty much the ONLY antidepressant that has ever helped me. Totally a life saver over and over for me. It is HIGHLY calming as well as anti-deprssing. That is because simultaneous to increasing serotonin and norepinephrine, is a beta adrenergic blocker (hence anti fear etc) BUT here is the real amazing thing about Doxepin - it is VERY anti- inflammatory. Neuroinflammation (brain inflammation) is a big issue in mental health problems. Doxepin - out if ALL dregs, addresses this best of all. Search pub med. Doxepin has saved my life many times over several decades."

   
10

Adriana77 (taken for 5 to 10 years) April 9, 2016

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For Insomnia: "Oh dear. I thought I would give Doxepin a try just to compare it to my usual low dose of Amitriptyline and see if I slept any better. I lasted on this (25mg) just one night, and with less than an hour of sleep. It felt more like a stimulant for me and at one stage I thought I might be experiencing a nasty frightening panic attack. I don't know what is was but it didn't agree with me. I find low dose Elavil very sedating next to Doxepin (and more sedating than Mirtazapine). I have never tried Trazodone. Best of luck. :)"

   
1.0

In Shock In Australia (taken for less than 1 month) April 1, 2016

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For Insomnia: "Wonderful good sleep...."

   
9.0

f2ffhjh cb no outcast Program (taken for 1 to 6 months) March 24, 2016

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For Anxiety: "I was experiencing very bad anxiety and was having panic attacks nearly everyday. I also had issues sleeping, I couldn't sleep more than 2 hours at a time. My doctor put me on 75mg once daily at bedtime. I feel like my old self. I am sleeping very well at night and I haven't had a panic attack in 8 months. Doxepin gave me my life back."

   
10

Gotribein16 (taken for 6 months to 1 year) March 20, 2016

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