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User Reviews for Doxepin

Also known as: Adapin, Silenor, Sinequan

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Doxepin.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Major Depressive Disorder 2 reviews 46 medications
   
10
Irritable Bowel Syndrome 4 reviews 139 medications
   
7.8
Urticaria 10 reviews 188 medications
   
7.7
Depression 12 reviews 80 medications
   
7.4
Insomnia 163 reviews 109 medications
   
6.7
Anxiety 11 reviews 63 medications
   
6.5
Reflex Sympathetic Dystrophy Syndrome 1 reviews 2 medications
   
3.0
Summary of Doxepin reviews 203 reviews 7.0

Reviews for Doxepin

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Silenor (doxepin) for Insomnia: "I have been on Silenor since shortly after it hit the market....2011. It has been life changing. I can nap now, and some nights I can even sleep without it, which never happened on any other sleep meds. I will say it took about 4 weeks when I initially started it for it to really do the job-those were a rough for weeks. I also have very good commercial insurance that only requires a $5.00 co pay for a 3 month supply; my old plan used to require $100 for a 39 day supply. Since it is not cost prohibitive, it works well."

   
8.0

Brownchic (taken for 5 to 10 years) January 13, 2017

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For Irritable Bowel Syndrome: "I have had ibs-d my entire life. Would get extremely sick as a kid and lose a lot of weight in short periods of time. The pain is sometimes unbearable at times. Nothing helped but to not eat for a few days. I've tried lots of different meds. Was out on this one for insomnia and wham it fixed my IBS in one dose. 10mg dose. I now poop like a normal person and can go out and not worry where the bathroom is all the time."

   
10

U.wish. (taken for 1 to 6 months) December 20, 2016

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For Insomnia: "I take it to help me stay asleep at night. It's done well. I just started it 4 days ago. Last night I was eating and almost choked cause I couldn't swallow. Has anyone else had any problems swallowing?"

   
8.0

Emily34 December 16, 2016

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For Insomnia: "I have seen many say their insurance will not cover the 3mg dose. Ask your doctor to prescribe 10mg capsule. It is prob. covered and will still work. 10 mg is still very small dose."

DavidSPumpkins December 8, 2016

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Silenor (doxepin) for Insomnia: "I have had depression, anxiety and insomnia issues for decades, and have tried many approaches for these issues, including psychological, sleep study, endocrine, chiropractic, acupuncture, herbal formulas, homeopathics, aromatherapy, exercise, meditation, diet, and too many depression and insomnia medications to count. While I have had some success, especially with more natural approaches, I found this past several years that NOTHING helped, or it didn't help for long. My doctor recently gave me some Silenor samples to try, and I was absolutely blown away by their efficacy. I took the lower dose of 3mg 30 minutes before bedtime and slept great all the way through the night, 8-9 hours! No side effects, either. I wish I could afford them!"

   
10

Carol Koe December 2, 2016

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For Insomnia: "Ok....OMG!! Sooo..let me just say look at all the insomniacs ( true diagnosed people by psyc docs)that have had great experience with this..benzos are terrible for you ...but doxepin has yet to wake me up ...has yet to not work..and has yet give me Dreams or night terrors...now if ur like me and you can go 3 days with zero sleep ...while trying trazadone and even seraquil.. You know restlessness and complete misery..once on doxipen I slept great...didn't get up groggy (8 hour sleep ideal per 25 mg tablet) and it even combats IBS and my case crohnes"

Stephbeezy (taken for 1 to 6 months) November 26, 2016

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Silenor (doxepin) for Insomnia: "This prescription had the opposite effect. It did not help me sleep at all, but made me want to climb the walls. Wasted $44. After insurance payment"

   
1.0

Anonymous November 19, 2016

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Silenor (doxepin) for Insomnia: "I have had severe insomnia for about 3 years. My physician gave me 2 sample packs of 6mg Silenor. I cut them in half to take 3mg as needed. They worked wonderfully and I finally got several good nights of sleep without the groggy feeling in the morning. After the samples were gone, I got my Rx filled and found out my insurance will not cover it. After having been awake for 36 hours straight, out of desperation, I paid an arm and a leg for the Silenor. The first tablet of the Rx worked but that's it. I Increased to taking 6 mg and it still didn't work. Still no sleep. I have given up on Silenor and have gone back to a different insomnia Rx that works sometimes but at least my insurance covers it it only costs me $5."

   
1.0

Robin Magee November 15, 2016

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Silenor (doxepin) for Insomnia: "I have been on Silenor for 6 months now. I have a ton of medications that I take for my Bipolar Type IIA with a Panic Disorder. They help, but my mind would never stop so that I could sleep well. I take Silenor with a couple of medications (which I will not list) at night and sleep fine. No side effects noticed, but I take so many medications during the day that I might not notice it. I have been dealing with my illness for about 20 years now, so side effects are not a huge deal to me because most go away after 30 days. Now, if they are too severe, then I will consult my Doctor. You have to give these types of medications a chance. It's not like taking a Tylenol for a headache."

   
10

NopeNotGonna November 9, 2016

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Silenor (doxepin) for Insomnia: "I was given a sample pack 3mg Silenor to help with my inability to stay asleep. I followed the instructions and unfortunately it did not seem to work for me. It made me very anxious and agitated during the night. I did sleep but kept waking up. In the morning I was very groggy and unsteady on my feet. I felt like I had been drugged and had a minor headache all day. I do not think I will take it again as it is obviously not the drug for me."

   
2.0

jbg154 (taken for less than 1 month) November 5, 2016

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Silenor (doxepin) for Insomnia: "Great product. I never had a problem falling asleep before, I can and always could fall asleep in 2 or 3 minutes. My problem was during the night when I would wake up at 2am and be up for the day. With Silenor I still wake up on occasion but I go right back to sleep. I have been taking it for months now, still works great. Not groggy the next day. If your problem is getting to sleep this might not be right for you. If your problem is staying asleep or falling back to sleep after waking up during the night then Silenor will be a big help."

   
10

jimig October 30, 2016

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Silenor (doxepin) for Insomnia: "Difficulty sleeping through nite I did sleep first night but then most of next day on silenor. 2nd night tossed and turned but slept for about 4 hours. Felt drugged the next day. Took 3rd night slept off and on. Felt horrible next day, tired, weak feeling, headache. Also leaves mouth extremely dry. Not going to take silenor any more."

   
9.0

MS407 October 29, 2016

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For Insomnia: "I was given Doxepin 50mg to help me sleep. It knocked me out - This is the zombie apocalypse of sleep meds. It worked very well, but kept working all the next day. I slept about 17 hours and felt extremely groggy when I got up. I wouldn't recommend it if you just have trouble falling to sleep. I need something milder so i can function the next day."

   
10

Chazzd (taken for less than 1 month) October 27, 2016

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For Irritable Bowel Syndrome: "I took 1 yesterday approx 11am (I work nights). It's 18:22 now & I'm still exhausted. Slept all day, night and today. I also had nightmares! HORRIBLE!! I'll NEVER take this again."

   
1.0

Toni D (taken for less than 1 month) October 25, 2016

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For Major Depressive Disorder: "I've taken almost every SSRI and even a few MAOI's. I started taking Doxepin, and Wow! I was finally sleeping the whole night through! Since I've been sleeping better, I am up at a normal hour. I am able to do the things that I used to do. I without a doubt, find Doxepin to be far superior to any of the antidepressants that I've ever been on. Plus, the anxiety I used to get at bedtime, always worrying if I am going to be able to sleep, is gone now. I hope that others have the positive effects that I now have."

Miss Trish (taken for 6 months to 1 year) October 24, 2016

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For Urticaria: "I had hives for over a year since moving to a new environment. After trying almost every antihistamine and taking 7 cycles of prednisone, I went to see a new allergist. She started me on xolair injections and doxepin to help with the any breakthrough itching. I started at 25mg at night and ended up at 75mg. I haven't had a hive since starting on the xolair and 75mg of doxepin. I am hesitant to decrease the doxepin because I have had the best solid sleep since I started taking it. Seriously if you have hives I would definitely recommend trying the doxepin - it is amazing."

   
10

Itchyincali October 10, 2016

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For Insomnia: "I was put on Doxepin 10mg, for wake up middle of night insomnia. Every time I've taken it( about 5), I'm knocked out and sleep heavy for about 9 hrs. Then I'm very groggy the next day and sleep off and on. The feeling rested and like I actually slept is great. But, it's almost too good. I'm going to ask my dr. To reduce to like 3mg."

   
8.0

Mikey the best October 9, 2016

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For Insomnia: "I've had sleep issues for years and after having multiple sleep studies done as well as nasal surgery to fix deviated septum, I tried a dental sleep appliance and a c-pap machine and nothing worked. I was finally given Doxepin - OMG LIFESAVER...6 drops per night and I am out like a light wake up around 5 hours later but refreshed and not tired. However, if I go off routine, as in different time-zones, late nights, it does take a while to get back on track...I'd be in a mental health institution if I hadn't found this as I was at the end of the rope and couldn't cope anymore being constantly exhausted."

   
10

ValC623 October 3, 2016

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For Insomnia: "at first my doc prescribed an amount which was too much (don't remember the dose) so he changed it to 10 mg. worked at first. i don't take it every night because i don't want to build a resistance. tonight i took 6 (60 mgs). that was 3 hours ago and i'm still awake. took xanax a little while ago. benzos don't work for me. took 30 mg of valium one night and was up at 2am cleaning cabinets. even my pharmacist was shocked when i told him."

   
2.0

very young widow October 1, 2016

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Silenor (doxepin) for Insomnia: "I have had chronic insomnia for 5 years. I struggle to fall asleep, and once I'm asleep, I never sleep longer than 45 minutes - 1 hour without waking up. I take Ambien when I can afford it, so I have to limit myself to only a few times a week. I was given a sample pack of Silenor about a year ago, but the online reviews made me not want to try it. I was desperate last night, so I tried one 3mg. My heart raced and it did not make me sleepy. I took another half 3mg. and finally dozed off about an hour later. The amazing thing is that even though I never felt sleepy from it like I do with Ambien, I actually slept for 3 straight hours on the Silenor. I do have a tiny headache today, so I don't know if I will take it again."

   
7.0

Daisybuttercup (taken for less than 1 month) September 30, 2016

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For Anxiety: "This drug was terrible, I would take it at night and fall right to sleep and when I get up in the morning im completely exhausted and dizzy. My balance is off and feel like im in a daze. I was extremely irritable. The entire day I was depressed and in a very very bad mood. Everything bothered me. My anxiety was terrible. Tremors in my hands and just feeling kind of loopy. Nightmares when sleeping. This drug did nothing of any benefit for me. I was taking it to help with my social anxiety and panic attacks."

   
2.0

metalman1980 September 17, 2016

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Silenor (doxepin) for Insomnia: "I have trouble sleeping from 3 - 6 am. I wake up and cannot go back to sleep creating the daytime symptoms of insomnia (see: http://www.mayoclinic.org/diseases-conditions/insomnia/basics/definition/CON-20024293 ). I rarely have trouble falling asleep. I have been taking LIQUID doxepin for 18+ months (along with a 5 mg time release melatonin) - 30 min before bedtime. The LIQUID has to be especially prescribed by your Dr and approved by your drug company. A 120 ml bottle is $79 - with medicare & drug co approval, my out of pocket (last bought in 6/2016) was $7! Much cheaper than Silenor. I am prescribed 0.6ml/night, but sometimes I take 0.5ml or less, & never over 0.7ml (rarely). Doxepin & melatonin work well to help me sleep from 10p-6a!"

   
9.0

asissman (taken for 1 to 2 years) September 17, 2016

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For Insomnia: "Started on doxepin 25 mg unlike everyone else I can't sleep keeps me awake and now I have itching from the med will this go away already have hives don't need more itching couldn't sleep now I really cant"

Anonymous September 11, 2016

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Silenor (doxepin) for Insomnia: "Silenor literally saved my life ! Before a month ago, I never had sleeping issues, but after recently moving in with my boyfriend in an apartment with neighbour's dogs that kept me up all night, there was a 2 week period where I literally didn't sleep at all. I was starting to feel extremely anxious, depressed, and as if I was losing all control of my life. Silenor is non-addictive, which made me feel more comfortable about taking it. I still woke up in the night some nights, but it put me to sleep no problem. It allowed me to get back on track with my sleep and daily routines."

Insomnia01 September 4, 2016

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For Insomnia: "Prescribed for nightmares and night terrors due to PTSD. trazadone gave me a horrible body buzz and made me feel like I wasn't in control of my faculties. Worse off, it didn't stop the nightmares, just made it harder to wake from them. Doxepin was prescribed at 25 mg capsule, increasing to 75mg over a period of a month. Stopped the nightmares and night terrors instantly, with no body buzz. In fact, I don't dream at all anymore, and I'm okay with that. Miracle drug. I was becoming desperate and fought sleep as long as I could so I didn't have nightmares. This saved my sanity."

   
10

SarahhLee (taken for 1 to 6 months) September 4, 2016

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