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Doxepin User Reviews & Ratings (Page 4)

Brand names: Silenor Adapin

Doxepin has an average rating of 6.2 out of 10 from a total of 433 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Doxepin

Commonly mentioned side effects
  • jbg...
  • Taken for less than 1 month
  • November 5, 2016

Doxepin for Insomnia "I was given a sample pack of 3 mg Silenor to help with my inability to stay asleep. I followed the instructions, and unfortunately, it did not seem to work for me. It made me very anxious and agitated during the night. I did sleep but kept waking up. In the morning, I was very groggy and unsteady on my feet. I felt like I had been drugged and had a minor headache all day. I do not think I will take it again, as it is obviously not the drug for me."

2 / 10
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  • Anonymous
  • January 2, 2011

Doxepin for Insomnia "I have been using 3mg Silenor for a week now. First thing I noticed was that dreams seemed more vivid. The other thing was waking early (4:00 - 5:00), going to the bathroom, and then trying to go back to sleep. I thought that I stayed awake, but the next time I looked at the clock, it was 7:00 or later. I am now getting 8 hours or even more of sleep some days. When I wake up, I want a cup of coffee right away. After having it, I feel good, and that feeling continues for the rest of the day. I never took other sleep medicines as I only have a sleep maintenance problem. This is a great medicine, and I would highly recommend it. I am a 64-year-old male who is in good health otherwise."

10 / 10
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73 Report
  • Tux...
  • April 19, 2019

For Insomnia "Even with the best sleep hygiene, I can go for weeks on end, not getting more than 2 solid hours because I wake up constantly, 6-8 times per night. Doxepin has almost completely solved my problem staying asleep and given my life back! Ambien and benzodiazepines are not effective for me, and trazodone gives me panic attacks. Doxepin 150 mg allows me to go to sleep 2 hours after I take it and get a good solid 6-8 hours. I have to make sure to take it 3 hours after any food. The only drawback is it makes me hungry, but I just go to bed and don’t give in to the hunger after I take my dose. Well worth it! I occasionally take it with clonazepam if I am having panic attacks. The perfect sleep medicine for me. Oh- it can raise your heart rate, so make sure to let your doctor know if your pulse increases or you feel heart palpitations."

9 / 10
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Frequently asked questions

  • Ols...
  • February 9, 2015

For Insomnia "Prescribed doxepin in detox/rehab after trazodone did not work well. 25 mg of doxepin works really well for me. 120 lb female, age 26. Helps with anxiety and keeps me asleep even if I wake up to pee or something. I have gained some weight, but I can't attribute it to the doxepin since I am only two months clean off opiates. But for addicts, definitely give it a try because it worked wonders for me. Non-habit forming too."

10 / 10
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56 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 17, 2013

For Insomnia "This medicine has helped me tremendously! This has been the only medicine that has helped me. The only part I don't like about it is that when I wake up, I have a really bad dry mouth. Other than that, it is great!"

10 / 10
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63 Report

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  • CRU...
  • August 6, 2015

For Insomnia "For fifteen years, I only slept 2 to 4 hours each night. I tried many medications and could not even sleep with barbiturates. I have been taking Doxepin now for ten years and sleep 7-8 hours each night. I take a high dose of 150 mg. The downside is constipation and some dizziness. A worthwhile trade-off."

10 / 10
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  • Dol...
  • July 19, 2017

For Insomnia "I have had insomnia since I was a teen, and I am turning 50 next month. My doctors had tried me on natural aids and almost every sleeping pill in the book. The sleeping pills would put me to sleep, but I could not stay asleep. Most nights I would get up about 1:00 a.m. for a bathroom trip and would be up for a few hours. Some nights I would get up to go to the restroom and stay up for the rest of the night. Then, my doctor prescribed doxepin. Thank goodness! I go to sleep, and even if I get up to go to the restroom during the night, I am able to go back to bed and sleep! I use the liquid and take 10 mgs each night and don't have any hangover the next day. The script costs me less than $5 for a 90-day supply. My insurance company would not cover Silenor."

10 / 10
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42 Report
  • Jos...
  • June 30, 2016

Doxepin for Insomnia "I took this to help with my insomnia. I work different hours at the hospital, and I haven't been able to overcome the insomnia on my days off. Silenor has helped me so far, I hope that it stays that way."

10 / 10
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  • Par...
  • August 29, 2019

Doxepin for Major Depressive Disorder "It’s the best antidepressant for major depression. I recommend it highly. I have no side effects. I take 250 mg a day in divided doses - one in the morning, one in the afternoon, and three at night. It took me a year to find it, and I love it. Thank you."

10 / 10
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35 Report
  • May...
  • Taken for 1 to 6 months
  • December 9, 2020

For Urticaria "Waking up every day with chronic hives all over my body (no known cause) for months that won't go away with Benadryl, Singulair, Allegra, and even Xolair, my new allergist suggested doxepin. At this point, I was willing to try anything that could make them stop. When I tell you I haven't had a hive on my body since starting doxepin, it's no joke. Doxepin has been a lifesaver and has helped tremendously with my chronic hives."

9 / 10
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28 Report
  • bnw...
  • October 8, 2010

Doxepin for Insomnia "So far, so good. I have earlier morning wake-up, probably related to a mood disorder. Unlike the addictive medicines that cause worsening of depression, so far Silenor, that has its roots as an antidepressant, allows me to get a little more shut-eye without worsening of my depression symptoms."

10 / 10
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  • Ray...
  • Taken for 6 months to 1 year
  • April 13, 2019

For Insomnia "I’ve suffered from insomnia since I was 6 years old. I didn’t get help for it until I was 23. I have tried tons of things, from sleep apnea testing to medication. Doxepin has been the only thing to help keep me asleep and helps me fall asleep faster. I don’t have any side effects from this medication either."

10 / 10
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  • Mic...
  • Taken for 6 months to 1 year
  • September 14, 2019

For Insomnia "33-year-old male here. Experienced bad insomnia for months, that was induced from an out-of-nowhere panic attack incident. If you are looking for a reset to get yourself sleeping regularly again, this stuff does the trick. You have to experiment around with the dosage. I started taking 25 mg each night, sometimes taking it twice a day. The first few days, you will feel sluggish in the morning, but that goes away after a week. Also, a little dry mouth."

9 / 10
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34 Report
  • Anonymous
  • Taken for less than 1 month
  • December 12, 2013

For Insomnia "I've been battling insomnia for almost 4 years. I had tried Ambien but always wound up digging in the fridge at 3 a.m. It made me sleepwalk really bad. Now with Doxepin, I'm able to sleep through the night and no digging in the fridge at 3 a.m."

10 / 10
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  • Anonymous
  • October 28, 2010

Doxepin for Insomnia "I had been using Ambien for years but gradually developed a tolerance to this medication. I was also frustrated with the frequency of waking during the night. My GP prescribed 6.0 Silenor tablets about two weeks ago and thus far, I am very pleased with the effect on sleep maintenance."

10 / 10
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65 Report
  • dru...
  • October 27, 2010

Doxepin for Insomnia "I have taken Silenor 4 times over the last 10 days as needed. I tried a little Doxepin twice before, and pure Doxepin gave me a headache and a hangover groggy effect. Silenor allows me to get 8 hours of sleep with no side effects, yay! It's a great medicine...finally. If you have trouble sleeping, then you should try it."

10 / 10
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72 Report
  • rho...
  • October 5, 2009

Doxepin for Insomnia "Sinequan (doxepin) works very well for insomnia, especially since it not only causes drowsiness, but also because it relieves anxiety. A lot of insomnia is caused by overthinking or not being able to stop thinking or fretting. This is a good medicine for that. The only thing is it has more side effects than some of the newer drugs."

9 / 10
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  • Sun...
  • Taken for less than 1 month
  • November 10, 2018

Doxepin for Insomnia "My sleep doctor gave me a sample. I waited until I got very sleepy and took it and got right into bed. An hour later, I still wasn't asleep, but I kept lying there. At some point, I must have gone to sleep, but I woke up about three hours later needing to go to the bathroom. Went back to bed, slept a couple of hours more, and woke up again needing to go to the bathroom. During my 'sleep,' I had continuous vivid dreams, and I never felt as if I really slept. When I got up, I felt bad all day today. I'm not going to give it another chance. I have been on Ambien CR for years, and it gives me an average of 7.5 hours of sleep. I wanted to try something new because I need to take an Ambien vacation from time to time because I become habituated to it, and it stops working so well."

1 / 10
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  • hec...
  • August 29, 2016

For Insomnia "I have tried at least 15 other pills that all come with the groggy feeling if taken too late at night and too high of a dose. While 10 mg is too much for me, it works and works too well and keeps me asleep all night, and I actually feel rested. I had to write this review after seeing so many low ratings."

10 / 10
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49 Report
  • Kts...
  • Taken for less than 1 month
  • March 24, 2017

Doxepin for Insomnia "I take oxazepam 30 mg as well as Bystolic for tachycardia, but it also helps put you to sleep. I still had issues going to sleep. I couldn't sleep, and my doctor added 6 mg of Silenor to my routine. Last night I took it, and it says to stay in bed for 30 minutes. Well, I did not listen, I got up to go to the entertainment room because I thought I was still awake enough to watch some TV. Next thing I knew, I had fallen asleep sitting up, and it was 7 am. It works so well. Tonight, I will definitely stay in bed the full 30 minutes to let it kick in. As for the kink in my neck, I'm going to get a chiropractic adjustment later."

9 / 10
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  • And...
  • Taken for 1 to 6 months
  • September 24, 2018

Doxepin for Insomnia "The doctor put me on Silenor to help me stay asleep. It isn't habit-forming, which was a huge concern for me. If I take it according to instructions, 3 hours no food and 30 minutes before bed, I sleep great. I usually get at least 7.5 hours of sleep on it, with waking for the restroom at least once, but I fall right back to sleep. I don't notice any changes to my mood, but I am also on something for anxiety, so it may help with any potential mood side effects."

8 / 10
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  • CJa...
  • Taken for 1 to 6 months
  • November 24, 2019

Doxepin for Insomnia "Doesn't do much to help you fall asleep, but helps you stay asleep if you wake up halfway through the night or if you wake up too early and can't sleep. I found that 6 mg added a good 1-2 hours to how long I slept, but 3 mg did not do much. I only take as needed (2-3 times per week). Only real side effect is sedation throughout the day if you get less than 7-8 hours of sleep or if your sleep is disrupted."

7 / 10
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32 Report
  • Pro...
  • Taken for 1 to 6 months
  • July 28, 2017

For Insomnia "Doxepin does not help me fall asleep. It does help me stay asleep. I suffer from anxiety and depression, and that's why I can't sleep. To those people who have experienced extreme tiredness the next day, this also happens to me even though I take it as the manufacturer suggests for sleep maintenance, which is to take it on a completely empty stomach 3 hours after a meal. Otherwise, the onset is delayed even further. By several hours, leading to next-day sedation even more. Even when taking it the proper way, it has a 15-hour half-life, which can still leave you tired and groggy the next day, which I also experience even taking it correctly."

4 / 10
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  • Ins...
  • September 4, 2016

Doxepin for Insomnia "Silenor literally saved my life! Before a month ago, I never had sleeping issues, but after recently moving in with my boyfriend in an apartment with neighbors' dogs that kept me up all night, there was a 2-week period where I literally didn't sleep at all. I was starting to feel extremely anxious, depressed, and as if I was losing all control of my life. Silenor is non-addictive, which made me feel more comfortable about taking it. I still woke up in the night some nights, but it put me to sleep no problem. It allowed me to get back on track with my sleep and daily routines."

9 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • November 25, 2015

For Insomnia "Had a brain injury, sleep 2 to 3 hours a night. Take doxepin 10 mg. I have found to take the capsule apart and dump out about 5 mg of medicine. I can sleep 6 to 7 hours and wake up feeling great. No hangover. Even if I wake up during the night, I can go back to sleep. This drug is wonderful if used correctly."

10 / 10
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47 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.