Comparing Fluoxetine vs Duloxetine
| Fluoxetine | Duloxetine |
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| Fluoxetine | Duloxetine |
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Prescription only
Fluoxetine may be used for the treatment of certain types of mood disorders and also some eating disorders. It is more likely to cause insomnia than drowsiness. Taking fluoxetine with other... View more |
Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
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| More about Fluoxetine | More about Duloxetine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Fluoxetine has an average rating of 7.4 out of 10 from a total of 2249 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect. |
Duloxetine has an average rating of 6.2 out of 10 from a total of 2470 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Fluoxetine side effects |
View all Duloxetine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Fluoxetine prices |
View all Duloxetine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Prozac | Cymbalta, Drizalma Sprinkle, Irenka | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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210 hours |
17 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 684 drugs are known to interact with Fluoxetine:
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A total of 635 drugs are known to interact with Duloxetine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 29, 1987 |
August 03, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.