Comparing Flexeril vs Valium

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Flexeril (cyclobenzaprine)	Valium (diazepam)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Flexeril (cyclobenzaprine)	Valium (diazepam)	Enter another drug to compare
Prescription only Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more	Prescription only Valium may be used occasionally to relieve anxiety and some other conditions such as acute muscle spasms and alcohol withdrawal. However, it is addictive and withdrawal symptoms can be severe... View more	Related suggestions Muscle Spasm (Involuntary Hypertonicity) Cyclobenzaprine Tizanidine Baclofen Methocarbamol Soma Zanaflex Popular comparisons Flexeril vs gabapentin Flexeril vs tramadol Flexeril vs methocarbamol Flexeril vs baclofen Flexeril vs tizanidine Flexeril vs metaxalone
More about Flexeril (cyclobenzaprine)	More about Valium (diazepam)
Ratings & Reviews
Flexeril has an average rating of 6.1 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 27% reported a negative effect.	Valium has an average rating of 8.6 out of 10 from a total of 342 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 8% reported a negative effect.
View all 237 reviews	View all 342 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Drowsiness (19.8%) Dry mouth (9.3%) Tiredness (5.5%) Depression (3.0%) Dizziness (3.0%) Sleepy (3.0%) Hallucinations (2.5%) View all Flexeril side effects	Anxiety (7.0%) Withdrawal (5.0%) Drowsiness (4.7%) Muscle spasms (2.3%) Tiredness (2.3%) Tremors (2.3%) Addiction (2.0%) View all Valium side effects
Drug Class
Skeletal muscle relaxants	Benzodiazepine anticonvulsants Benzodiazepines
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	Oral tablet
Brand Names
Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine	Other diazepam brands include: Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Libervant, Valtoco
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
72 hours	70 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	4 Some potential for abuse Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
Pregnancy Category
B Category B No proven risk in humans See the full pregnancy warnings document.	D Category D Positive evidence of risk See the full pregnancy warnings document.
Drug Interactions
A total of 451 drugs are known to interact with Flexeril: 92 major drug interactions (471 brand and generic names) 353 moderate drug interactions (1412 brand and generic names) 6 minor drug interactions (13 brand and generic names)	A total of 525 drugs are known to interact with Valium: 32 major drug interactions (166 brand and generic names) 447 moderate drug interactions (1660 brand and generic names) 46 minor drug interactions (386 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness... View more	Grapefruit and grapefruit juice may interact with diazePAM and lead to potentially dangerous side... View more
Disease Interactions
Cardiovascular disease Anticholinergic effects	Acute alcohol intoxication Closed-angle glaucoma Drug dependence Renal/liver disease Respiratory depression Seizures Prolonged hypotension Myasthenia gravis Renal/liver disease Depression Obesity Paradoxical reactions
First Approval Date
August 26, 1977	November 15, 1963
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Drug images Support group	Side effects Drug interactions Dosage Pricing and coupons Pregnancy warnings Breastfeeding warnings Drug images Support group
Patient Resources
Flexeril uses	Valium uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Muscle Spasm Sciatica	Anxiety Hyperekplexia Endoscopy or Radiology Premedication Alcohol Withdrawal Seizures Status Epilepticus ICU Agitation Light Anesthesia Light Sedation Muscle Spasm Night Terrors Seizure Prevention Temporomandibular Joint Disorder Tetanus show all

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Flexeril vs Valium

See also:

Paracetamol

Tylenol

Botox

Robaxin

Valium

Advil

Voltaren

Aleve

Zanaflex

Soma

Further information

Comparing Flexeril vs Valium

See also:

Further information

Compare Drugs