Erythromycin Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Erythromycin	Amoxicillin	Metronidazole	Enter another drug to compare

Erythromycin

Amoxicillin

Metronidazole

Prescription only

Prescribed for Bronchitis, Bowel Preparation, Bacterial Endocarditis Prevention, Bartonellosis, Bullous Pemphigoid, Campylobacter Gastroenteritis, Chancroid, Chlamydia Infection, Dental Abscess... View more

Prescription only

Amoxicillin is a penicillin-type antibiotic that may be used to treat infections caused by susceptible bacteria. It is usually well tolerated, but a rash is a common side effect. Prescribed for... View more

Prescription only

Metronidazole is an antibiotic that is particularly effective at treating infections caused by susceptible anaerobic bacteria and parasites. Alcohol and products containing propylene glycol should... View more

More about Erythromycin

More about Amoxicillin

More about Metronidazole

Ratings & Reviews

Erythromycin has an average rating of 6.1 out of 10 from a total of 67 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 31% reported a negative effect.

Amoxicillin has an average rating of 6.4 out of 10 from a total of 367 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 29% reported a negative effect.

Metronidazole has an average rating of 6.0 out of 10 from a total of 2432 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 29% reported a negative effect.

View all 67 reviews

View all 367 reviews

View all 2432 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (20.9%)
Upset stomach (19.4%)
Diarrhea (17.9%)
Vomiting (11.9%)
Stomach pain (10.4%)
Sick (9.0%)
Dizziness (7.5%)

View all Erythromycin side effects

Diarrhea (13.4%)
Nausea (7.9%)
Pain (7.4%)
Headaches (6.8%)
Tiredness (6.0%)
Upset stomach (5.2%)
Yeast infection (4.4%)

View all Amoxicillin side effects

Nausea (33.8%)
Headaches (21.1%)
Dizziness (13.9%)
Diarrhea (12.4%)
Bad taste (10.2%)
Tiredness (9.7%)
Metallic taste (8.8%)

View all Metronidazole side effects

Drug Class

Macrolides

Aminopenicillins

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	3 tablet
Strength	250 mg
Per unit^*	$16.98
Cost^*	$50.94

View all Erythromycin prices

Quantity	4 capsule
Strength	500 mg
Per unit^*	$2.61
Cost^*	$10.42

View all Amoxicillin prices

Quantity	4 tablet
Strength	500 mg
Per unit^*	$2.69
Cost^*	$10.77

View all Metronidazole prices

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Dosage Forms

Injectable powder for injection
Oral delayed release capsule
Oral delayed release tablet
Oral granule for reconstitution
Oral suspension
Oral tablet

Oral capsule
Oral powder for reconstitution
Oral tablet
Oral tablet, chewable
Oral tablet, extended release

Intravenous solution
Oral capsule
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

2 hours

1.7 hours

20 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 683 drugs are known to interact with Erythromycin:

207 major drug interactions (601 brand and generic names)
412 moderate drug interactions (1704 brand and generic names)
62 minor drug interactions (297 brand and generic names)

A total of 64 drugs are known to interact with Amoxicillin:

7 major drug interactions (25 brand and generic names)
50 moderate drug interactions (273 brand and generic names)
7 minor drug interactions (35 brand and generic names)

A total of 391 drugs are known to interact with Metronidazole:

13 major drug interactions (36 brand and generic names)
373 moderate drug interactions (1217 brand and generic names)
5 minor drug interactions (20 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Food decreases the levels of erythromycin in your body. Take erythromycin on an empty stomach at... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during... View more

Disease Interactions

First Approval Date

June 24, 1964

January 18, 1974

July 18, 1963

WADA Class View classifications

N/A

More Information

Patient Resources

Amoxicillin uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Erythromycin Alternatives Compared

See also:

Amoxicillin/clavulanate

Sulfamethoxazole/trimethoprim

Ozempic

Cefdinir

Guaifenesin

Levofloxacin

Augmentin

Ceftriaxone

Ciprofloxacin

Doxycycline

Further information

Erythromycin Alternatives Compared

See also:

Further information

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