Comparing Clorazepate vs Hydroxyzine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clorazepate	Hydroxyzine	Enter another drug to compare

Clorazepate

Hydroxyzine

Prescription only

Prescribed for Alcohol Withdrawal, Anxiety, Seizure Prevention, Seizures, Epilepsy. Clorazepate may also be used for purposes not listed in this medication guide.

Prescription only

Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more

More about Clorazepate

More about Hydroxyzine

Ratings & Reviews

Clorazepate has an average rating of 9.1 out of 10 from a total of 56 ratings on Drugs.com. 89% of reviewers reported a positive effect, while 4% reported a negative effect.

Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1405 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect.

View all 56 reviews

View all 1405 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Clorazepate side effects

Drowsiness (21.8%)
Tiredness (10.5%)
Sleepy (6.3%)
Anxiety (5.6%)
Nausea (3.8%)
Dizziness (3.7%)
Dry mouth (3.1%)

View all Hydroxyzine side effects

Drug Class

Benzodiazepines

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	6 tablet
Strength	15 mg
Per unit^*	$3.00
Cost^*	$17.99

View all Clorazepate prices

Quantity	4 tablet
Strength	hydrochloride 25 mg
Per unit^*	$2.74
Cost^*	$10.95

View all Hydroxyzine prices

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Dosage Forms

Oral tablet

Intramuscular solution
Oral capsule
Oral syrup
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

93 hours

7 hours

CSA Schedule ¹ View glossary of CSA terms

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Category N Not classified

See the full pregnancy warnings document.

Drug Interactions

A total of 505 drugs are known to interact with Clorazepate:

31 major drug interactions (163 brand and generic names)
440 moderate drug interactions (1648 brand and generic names)
34 minor drug interactions (219 brand and generic names)

A total of 581 drugs are known to interact with Hydroxyzine:

93 major drug interactions (368 brand and generic names)
484 moderate drug interactions (1992 brand and generic names)
4 minor drug interactions (16 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of clorazepate such as dizziness, drowsiness... View more

Alcohol can increase the nervous system side effects of hydrOXYzine such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

June 23, 1972

April 12, 1956

WADA Class View classifications

N/A

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Clorazepate vs Hydroxyzine

See also:

Lexapro

Xanax

Xcopri

Cymbalta

Lamictal

Lyrica

Depakote

Ativan

Keppra

Klonopin

Further information

Comparing Clorazepate vs Hydroxyzine

See also:

Further information

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