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Cleocin HCl Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cleocin HCl (clindamycin) Amoxicillin Doxycycline
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cleocin HCl (clindamycin) Amoxicillin Doxycycline
Prescription only

Prescribed for Bacterial Endocarditis Prevention, Aspiration Pneumonia, Bacteremia, Babesiosis, Bacterial Infection, Bacterial Vaginosis, Bone infection, Deep Neck Infection, Diverticulitis... View more

Prescription only

Amoxicillin is a penicillin-type antibiotic that may be used to treat infections caused by susceptible bacteria. It is usually well tolerated, but a rash is a common side effect. Prescribed for... View more

Prescription only

Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of their... View more

More about Cleocin HCl (clindamycin) More about Amoxicillin More about Doxycycline
Ratings & Reviews

Cleocin HCl has an average rating of 8.8 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect.

Amoxicillin has an average rating of 6.4 out of 10 from a total of 366 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 29% reported a negative effect.

Doxycycline has an average rating of 6.4 out of 10 from a total of 1635 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 27% reported a negative effect.

View all 4 reviews

View all 366 reviews

View all 1635 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Cleocin HCl side effects

View all Amoxicillin side effects

View all Doxycycline side effects
Drug Class
Generic Availability
Lower cost generic approved

Lower cost generic

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 100 capsule
Strength 75 mg
Per unit* $0.34
Cost* $33.84

View all Cleocin HCl prices

Quantity 4 capsule
Strength 500 mg
Per unit* $2.61
Cost* $10.42

View all Amoxicillin prices

Quantity 2 tablet
Strength hyclate 100 mg
Per unit* $6.62
Cost* $13.23

View all Doxycycline prices

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Dosage Forms
  • Oral capsule
  • Oral capsule
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet, chewable
  • Oral tablet, extended release
  • Injectable powder for injection
  • Oral capsule
  • Oral delayed release capsule
  • Oral delayed release tablet
  • Oral powder for reconstitution
  • Oral tablet
Brand Names
Other clindamycin brands include: Cleocin, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage Amoxil, Apo-Amoxi Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, Okebo, Oracea, Oraxyl, Targadox, Uracil, Vibramycin View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

3.4 hours

1.7 hours

23 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
B
Category B No proven risk in humans

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
D
Category D Positive evidence of risk

See the full pregnancy warnings document.
Drug Interactions

A total of 111 drugs are known to interact with Cleocin HCl:

  • 6 major drug interactions (15 brand and generic names)
  • 102 moderate drug interactions (386 brand and generic names)
  • 3 minor drug interactions (9 brand and generic names)

A total of 58 drugs are known to interact with Amoxicillin:

  • 7 major drug interactions (25 brand and generic names)
  • 44 moderate drug interactions (259 brand and generic names)
  • 7 minor drug interactions (35 brand and generic names)

A total of 226 drugs are known to interact with Doxycycline:

  • 22 major drug interactions (60 brand and generic names)
  • 199 moderate drug interactions (2220 brand and generic names)
  • 5 minor drug interactions (21 brand and generic names)
Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
First Approval Date

N/A

January 18, 1974

December 05, 1967
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources

N/A
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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