Cimetidine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cimetidine	Wegovy (semaglutide)	Mounjaro (tirzepatide)	Enter another drug to compare

Cimetidine

Wegovy (semaglutide)

Mounjaro (tirzepatide)

Prescription and OTC

Prescribed for Duodenal Ulcer, GERD, Duodenal Ulcer Prophylaxis, Cutaneous Mastocytosis, Bronchogenic Carcinoma, Erosive Esophagitis, Human Papilloma Virus, Indigestion, Laryngopharyngeal Reflux... View more

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Cardiovascular Risk Reduction. Wegovy may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide.

More about Cimetidine

More about Wegovy (semaglutide)

More about Mounjaro (tirzepatide)

Ratings & Reviews

Cimetidine has an average rating of 7.7 out of 10 from a total of 21 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 19% reported a negative effect.

Wegovy has an average rating of 7.6 out of 10 from a total of 495 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 15% reported a negative effect.

Mounjaro has an average rating of 8.5 out of 10 from a total of 1339 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 21 reviews

View all 495 reviews

View all 1339 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Cimetidine side effects

Nausea (32.7%)
Constipation (14.3%)
Vomiting (10.5%)
Diarrhea (9.7%)
Tiredness (6.5%)
Headaches (6.3%)
Heartburn (6.1%)

View all Wegovy side effects

Nausea (16.5%)
Constipation (11.5%)
Diarrhea (8.3%)
Upset stomach (4.6%)
Loss of appetite (4.5%)
Vomiting (4.5%)
Burping (4.1%)

View all Mounjaro side effects

Drug Class

H2 antagonists

GLP-1 Agonists (Incretin Mimetics)

GLP-1 Agonists (Incretin Mimetics)

Generic Availability

Lower cost generic

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	10 tablet
Strength	400 mg
Per unit^*	$1.82
Cost^*	$18.16

View all Cimetidine prices

Quantity	2 mL
Strength	0.25 mg/0.5 mL (0.25 mg dose)
Per unit^*	$725.05
Cost^*	$1,450.10

View all Wegovy prices

Quantity	2 mL
Strength	2.5 mg/0.5 mL
Per unit^*	$581.34
Cost^*	$1,162.67

View all Mounjaro prices

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Dosage Forms

Oral liquid
Oral tablet

Subcutaneous solution

Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

2.5 hours

168 hours

120 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 487 drugs are known to interact with Cimetidine:

42 major drug interactions (144 brand and generic names)
295 moderate drug interactions (1149 brand and generic names)
150 minor drug interactions (1824 brand and generic names)

A total of 273 drugs are known to interact with Wegovy:

15 major drug interactions (34 brand and generic names)
257 moderate drug interactions (1452 brand and generic names)
1 minor drug interactions (10 brand and generic names)

A total of 414 drugs are known to interact with Mounjaro:

15 major drug interactions (34 brand and generic names)
398 moderate drug interactions (2273 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Food may affect the absorption of semaglutide when taken orally. It is recommended that oral... View more
Talk to your doctor before using alcohol together with semaglutide. Alcohol may affect blood... View more

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more

Disease Interactions

First Approval Date

August 16, 1977

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Cimetidine uses

Wegovy uses

Mounjaro uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Cimetidine Alternatives Compared

See also:

Protonix

Nexium

Repatha

Pepcid

Prilosec

Carafate

Pepto-Bismol

Prevacid

Zantac

Dexilant

Further information

Cimetidine Alternatives Compared

See also:

Further information

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