Wegovy and Constipation: What Users Say

• Bac...
• Taken for 1 to 6 months
• March 9, 2023

For Weight Loss (Obesity/Overweight) "I started Wegovy 6 weeks ago at 0.25 mg for 4 weeks, and for the last 2 weeks at 1 mg. I started at 211 lbs and am now 197 lbs, so have lost 14 lbs and counting in 6 weeks. Not bad! Symptoms I've experienced include being slightly more tired than usual on the day of the injection, and some constipation at first but I use Miralax if there's an issue and it works fine for me. I haven't had any extreme nausea, but the injection definitely makes me less hungry and there are certain foods that I feel slightly queasy even considering eating-like high-fat foods-so I don't eat them. I eat a lot more fruits and vegetables and get full very quickly. I work out 4-5 days a week, my energy has been good and I feel like I'm getting back to my old self. I'd like to be about 135 lbs eventually. Wegovy has been a lifesaver. I'm 55 years old and had considerable cravings, especially at night. I'm happy to be free of them. I hope to make my new habits permanent."

• Mom...
• Taken for 1 to 6 months
• December 29, 2021

For Weight Loss (Obesity/Overweight) "Just took my last injection of month 5, 1.7. I have lost about 25-30 lbs along with 3-5 days a week at the gym. Definitely curbs your appetite. The nausea is very real! Each month I thought it would get easier. It never does. A couple times I puked for hours. Lots of belching. In the beginning, a little constipation. The first day or 2 after the injection, you can feel fatigue. It works for weight loss if you can tolerate the nausea. This will be my last month. I have a 6-month prescription but I can’t deal with the nausea anymore."

• Jed...
• Taken for 1 to 6 months
• December 15, 2021

For Weight Loss (Obesity/Overweight) "Halfway through the 1.7mg dose. Been on for about 4.5 months. Have lost a total of 35 pounds. My weight loss has slowed down since on the 1.7 dose. Still losing but not as quickly as in the beginning. Have no real interest in food anymore. Sometimes have to eat when not hungry due to low blood sugar (had this prior to Wegovy use). Been trying to lose weight for months. Wegovy is the only thing to work for my obesity due to medical issues. Have noticed off and on fatigue, dizziness, constipation, stomach pain, gas, belching, and hair loss. Can no longer eat fried, greasy food without feeling sick, which is good. Now I want healthy food instead."

• fin...
• Taken for 1 to 6 months
• January 17, 2022

For Weight Loss (Obesity/Overweight) "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

• Slw...
• Taken for 1 to 6 months
• February 11, 2022

For Weight Loss (Obesity/Overweight) "I'm on my 13th week at 1mg now. I love it. Yes, I was nauseated at first, but the quick weight loss results made me want to continue. At this dosage, I am not really hungry for food, and if I do feel hungry, it doesn't take much food for me to feel satisfied. I have really cut my portions and also use high fiber, high protein foods. Constipation is real, people, laxatives help. I make good food choices now and am down 25 lbs. I want to keep going, but the coupon has run out, and now my out-of-pocket cost with insurance is around $900. I am so disappointed to have to stop and worried about gaining back or not losing anymore. Novo really needs to make this affordable. The price is ridiculous, and millions of people are dying from comorbidities to obesity every day. I have high-end insurance, and still cannot afford the copays."

• MRS...
• Taken for 1 to 6 months
• January 10, 2022

For Weight Loss (Obesity/Overweight) "I have been taking Wegovy since August 2021. I am down 45 pounds. I did low carb with this which has really helped me to lose the weight I have wanted to lose. The side effects are very real, extreme constipation and nausea for two days after injection. The doctor prescribed Zofran for the nausea and I have taken a stool softener for the constipation. All things said, it really helped curb my appetite. But you have to diet with it."

• Fin...
• Taken for 1 to 6 months
• July 5, 2022

For Weight Loss (Obesity/Overweight) "57-year-old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks), but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre-loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with an ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many 'units' to administer per week, just cut it in half, say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation, and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

• Tou...
• Taken for less than 1 month
• March 14, 2023

For Weight Loss (Obesity/Overweight) "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy because she feels nausea that severe should be considered a negative side effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as Miralax. I am 57, menopausal, and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out, but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that it's embarrassing, stools are like a rock, and the worst feeling is chest tightness. I had so hoped I would be one of those without adverse side effects, but I am not."

• usm...
• Taken for 1 to 6 months
• November 29, 2022

For Weight Loss (Obesity/Overweight) "At this time, I’m on my 5th week of the maintenance dose. The only side effect I’ve had is occasional constipation, but as a 25-year medical professional, I know how to deal with it medically and in conjunction with my VA doctor and pharmacist. At times, I would get hypoglycemic, but again I knew how to combat that. At this dose, I find myself somewhat more fatigued but I can deal with that. Cat naps usually do the trick. I started at 393 and 6’3”. I’m 56 years old. I’m down to 349 since I started, which for me is great. I have critical low testosterone and can’t take testosterone due to my history of pulmonary embolisms. So, I don’t mind losing only 2 pounds a week. I can now walk so much better and farther. I’m 95% VA disability rated, and I’ll tell you, I feel and look so much better after starting to use Wegovy. The VA truly cares for us veterans no matter what you hear. Stay blessed and hang in there."

• LMH...
• Taken for less than 1 month
• November 8, 2021

For Weight Loss (Obesity/Overweight) "So far so good. I'm only on week 2, but am down 10 pounds with a combination of exercise and a 1200 cal/day diet. The symptoms I've had so far are tiredness, constipation, and some hair falling out (Dr. will be checking my vitamin levels to make sure I don't need supplements with the new diet). It definitely curbs my appetite, which is huge with my diet essentially cut in half. I am looking forward to seeing sustained results."

• Joh...
• Taken for 1 to 6 months
• March 9, 2025

For Weight Loss (Obesity/Overweight) "I have been on Wegovy now for two months and have lost 20 pounds. The only issue I have had since starting is constipation. I tried various laxatives, but it took a long time for them to kick in. They have started to work, which is awesome as I was getting concerned. I am a 75-year-old male and started at 235 pounds. I have dropped 20 pounds so far and would like to lose that much again. I have more energy, have dropped from size 40 pants to a very loose 38. As I said, my only issue has been the constipation, but maybe I need to increase my water intake to offset that. I would recommend this product, but the side effects are not the same for everyone. Best of luck to all."

• Anonymous
• Taken for 1 to 6 months
• June 20, 2024

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 5 months. I have nothing but good things to say about it. I have lost almost 50 lbs and it has given me my life back. I was overweight and depressed for years after having my last child. The only side effect I have had is some occasional constipation. This medication is amazing!"

• rdm...
• Taken for less than 1 month
• March 7, 2023

For Weight Loss (Obesity/Overweight) "I had my second 0.25 shot 2 days ago. My appetite is definitely less, and I am able to stay on my 1200 calorie lower carb diet without the hunger that haunted me before Wegovy. I also take a multivitamin once daily. I have lost about 7 lbs. I have been constipated, but nowhere near the amount that opioids do. I do chart my food intake and sip fluids throughout the day. Exercise three days a week. So far, so good."

• Bit...
• Taken for 6 months to 1 year
• March 23, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."

• JAO...
• Taken for 1 to 6 months
• June 14, 2023

For Weight Loss (Obesity/Overweight) "I had been on this drug for 4 months. Typical escalation dose until month 4, I stayed on the 1 mg. The side effects were rough since increasing to 1 mg. So much nausea, worsened reflux, constipation, bloating, burping, and indigestion. I vomited once, but there were a few times I almost did. In the last few weeks, I noticed hair loss. Noticed skin tags that I have never had...like 3 grew since the med. Weird. Oh, and I had serious issues with certain smells. I had to change out the hand soaps in my house 5 times. If I smell rubbing alcohol, I am instantly nauseous. Just looking at the Wegovy box before injecting would make me dizzy and nauseous. So weird. Difficult to eat healthy on this med due to side effects, and only able to tolerate simple carbs, low-fat diet. Also hard to work out when feeling so nauseous...so didn't think it was contributing to my health. Has not really contributed to weight loss, and appetite is almost the same as before med."

• Me ...
• Taken for 1 to 6 months
• January 25, 2022

For Weight Loss (Obesity/Overweight) "Nausea, diarrhea, constipation, sulfur burps, fatigue, loss of appetite, super sensitive to smells, I have to make myself eat enough. It's like morning sickness, only it's 24/7. Zofran helps for about 6 hours. Cannot tolerate much besides chicken broth and Brussels sprouts. No fried, fatty, oily, spicy foods. Need to stay hydrated with water. Ginger ale helps. I'm up to a 1 mg dose and 14th week. This nausea is constant and impacts my daily routine significantly. However, it is the only effective weight loss option that's worked in 26 years of diets and exercise and eating healthy. I will not give up. The weight is killing me, and I needed this medication. I started at 221 lbs. and now I'm at 194.3 lbs. BMI is close to pre-obesity, and I know I'll cry the day I hit it. Full disclosure, I'm disabled in part due to my weight. There is no way I could have worked and taken Wegovy with the severity of my nausea and fatigue. But the mobility and breathing issues are improving."

• Jen...
• Taken for 1 to 6 months
• February 16, 2022

For Weight Loss (Obesity/Overweight) "I am on my first week of the 2.4 dose (so I am just starting month 5). My weight loss seems a bit slower than others (story of my life), BUT I am still losing! I’ve lost 26 pounds in 5 months with making few modifications to my diet. I eat similarly to how I did before, but my portions are much smaller. I have experienced some side effects, but everyone’s experience is different. I can usually combat the upset stomach and gas with Gas-X and Pepto. I have experienced constipation, but that’s honestly something I’ve battled all of my adult life. Miralax in my morning tea or coffee certainly helps with that. Bottom line for me is this… the occasional side effects are 100% worth the results I’m seeing!"

• Hoo...
• Taken for 1 to 6 months
• February 14, 2025

For Cardiovascular Risk Reduction "I wanted to lose about 45 pounds and asked my cardiologist to prescribe Wegovy because I have cardiovascular disease. I'm on a Medicare Advantage insurance, and the med was approved. I have been on it for 2.5 months and am down 25 pounds. I haven't had any noticeable side effects except insane constipation. I already had issues with that, so I take a Linzess every morning, and that does the trick. I started noticing the curbed appetite the day after my first dose. It's not as intense now, but I have zero food noise, and I just can't eat like I used to. I have had migraines for 35+ years, and I haven't had one since starting Wegovy. I don't think it's my weight loss or improved eating habits, I think it's the medication. Before I became disabled, I was a size 4 and ate very healthy, but had 12+ migraine days per month. I inject my dose in the stomach each week and have never had any reaction to the injection. Overall, I am thrilled with Wegovy so far."

• Weg...
• Taken for 1 to 2 years
• August 4, 2024

For Weight Loss (Obesity/Overweight) "I started on Wegovy on the 1st of June 2023. My weight was 109.7 kg. I started losing 1-2 kg per week at the start. Afterwards, the loss was more between 0.2-0.7 kg. I did not attend the gym or do exercises last year. I have started going to the gym now. My weight now in August 2024 is 73 kg. I have not experienced any side effects besides constipation. The plan is that after the end of August, I will start going down on the dosage and will fully stop taking it at the end of this year. My doctor told me that some of her other patients who have fully stopped it have managed to keep their weight by regularly exercising and by continuing to eat healthy, not overeating."

• Dan...
• Taken for 1 to 6 months
• April 5, 2023

For Weight Loss (Obesity/Overweight) "I wanted to warn people of the side effects, as my doctor did not prepare me for this med. I am very glad I didn't try to work, otherwise, I would have lost my job or, at the very least, been written up for various reasons. On it for a month. I tried spacing out the second shot and never ended up taking the last injection. Side effects: severe fatigue, severe hair loss, decreased hormones, severe headaches, changes in your sleep architecture, bad nightmares for all sleep, naps, and overnight. Warning: if you have PTSD, that may mess with you. Bladder urgency and UTI symptoms started on day 3 and were constant the whole time on the med, I had to take AZO. Bloating, burping, throwing up, and all food smells make you sick, severe constipation, hypoglycemia, and increased binge eating. I also had increased topical psoriasis and arthritis pain. Started having problems with my foot and wondering if it's impacting ligaments. I am getting that checked out. Did not reduce the need to eat, no weight loss."

• Wor...
• Taken for 6 months to 1 year
• February 25, 2025

For Weight Loss (Obesity/Overweight) "Beginning weight was 234 and began at 0.25 in June 2024, and just began 2.4 today at 177. Been going up very slowly, but weight loss has slowed way down. Still have 17 pounds to lose, but prefer 27 more. Have gone from 2XL/Size 22 to size 14. Have dealt with nausea, headaches, occasional constipation/diarrhea, depending on what I eat. Small meals, five times a day, plus drinking lots of water is key. I get extremely tired the day or two after taking the shot. I take the shot at night, hoping to be at my goal weight by the end of May 2025. 63-year-old woman and all blood work now within normal limits."

• Arc...
• Taken for less than 1 month
• June 19, 2023

For Weight Loss (Obesity/Overweight) "Began Wegovy three weeks ago, have lost 11 pounds so far. Ready to move up to the 0.5 mg dose. Side effects have been minimal, some tiredness and a bit of constipation, but nothing awful. The key is to listen to your body. If you feel full, then stop eating. That's Wegovy doing its job. Don't ignore it. Good luck to all."

• Rem...
• Taken for 1 to 6 months
• January 3, 2025

For Weight Loss (Obesity/Overweight) "Other medications I am required to take have caused increased appetite and subsequently weight gain. Almost immediately after starting Wegovy (0.5), I wasn't hungry, was not craving carbs or sweets, and was able to eat good food and be satisfied with less than half the amount of food I usually had. In seven weeks, I have lost 9 kilos. It seems effortless after years of dieting. Side effects are definitely constipation and dehydration. I did have a problem with the pen on week 4, wasn't sure I got the dosage, but seems ok so far."

• Fay...
• Taken for less than 1 month
• January 22, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy 2 weeks ago. I have acid reflux and constipation. I took 1 magnesium/citrate gummy to help with the constipation and ended up with severe cramping with diarrhea in the middle of the night. The acid reflux happens every evening, and acid reflux meds cause constipation. I’m not enjoying the Wegovy."

• Ano...
• Taken for 1 to 6 months
• May 7, 2025

For Weight Loss (Obesity/Overweight) "I have done very well with Wegovy. I am now on the highest dose. This is the 3rd week on the highest dose, and I have lost 25 lbs in 4 months, and I am still losing. I have had some common issues such as nausea, diarrhea in the first month, but that went away. Then in the 2nd month, I had minor stomach pain, and the diarrhea changed to constipation. I am still experiencing constipation but managing it with fiber. Other than these issues, I am happy with the medication, and I feel so much better!"