Wegovy and Constipation: What Users Say (Page 2)
Reviews for Wegovy
- Wor...
- Taken for 6 months to 1 year
- February 25, 2025
For Weight Loss (Obesity/Overweight) "Beginning weight was 234 and began at 0.25 in June 2024, and just began 2.4 today at 177. Been going up very slowly, but weight loss has slowed way down. Still have 17 pounds to lose, but prefer 27 more. Have gone from 2XL/Size 22 to size 14. Have dealt with nausea, headaches, occasional constipation/diarrhea, depending on what I eat. Small meals, five times a day, plus drinking lots of water is key. I get extremely tired the day or two after taking the shot. I take the shot at night, hoping to be at my goal weight by the end of May 2025. 63-year-old woman and all blood work now within normal limits."
- Dut...
- Taken for 1 to 6 months
- September 6, 2024
For Weight Loss (Obesity/Overweight) "I'm almost 2 meters long, and when I started, I was more than 157 kg. Within 11 weeks, I lost 22 kg. Almost every week, I lost 1.5 kg and more after the big water loss. For me, it's an addition to the bigger plan. Yes, I use Wegovy (now on 1 mg), but I also go to the gym 5 times a week and add some hour-long walks to my day. And yes, I also have a strict timeframe where I have my meals. And yes, they are mostly veggies and some yogurt with some granola for some fiber. I had some side effects like heartburn, burping, constipation, and I'm more tired than before. But I think that's a normal thing to process, especially when you make the transition. If you are seriously overweight, please consider this medicine as a small part of the bigger plan!"
Frequently asked questions
- 6 Wegovy side effects you need to be aware of
- Ozempic Mounjaro Wegovy & Zepbound: Weight Loss Compared
- Wegovy vs Ozempic: Which is Right for You?
- How long until I'll lose weight with Wegovy?
- Why...
- Taken for 1 to 6 months
- April 10, 2022
For Weight Loss (Obesity/Overweight) "I tried the 0.25 dose and experienced constipation. The next month, my doctor prescribed 0.5. Not only did the constipation continue, there was horrible burping, severe indigestion that caused me to take a day off work. After that, I didn't eat much, just drank water, peppermint tea, smoothies. In addition to those side effects, there's also the possibility of life-threatening side effects. While it was easy to administer, I'd rather stay fat than endure the pain of side effects or additional medical issues to increase weight loss."
- Zee...
- Taken for 1 to 2 years
- February 7, 2025
For Weight Loss (Obesity/Overweight) "70 pounds down and maintained for over a year now. Wegovy in conjunction with a high-protein, low-carb food plan does it right. I am convinced that the majority of negative outcomes are due to people just shooting the drug and making no changes to their diet. Stay off the sugar, keep your carb intake to vegetables and limited fruits only. Constipation avoided by adding a magnesium citrate supplement. (I use Calm)."
- Kat...
- Taken for 1 to 2 years
- July 3, 2025
"I’ve been on Wegovy for just over a year. At first, I experienced heartburn and a little bit of nausea and fatigue. I only threw up once. I’m adjusted to it now, and it’s keeping the weight I lost off, which was 60 pounds. I used to get migraines the day after injection, sometimes a couple of days in a row. I have found that if I take the injection earlier in the day around lunchtime and I also eat around the time I take the injection, I have fewer headaches. Please remember, you should avoid greasy foods because that causes the nausea and the heartburn, although I do enjoy an occasional hamburger. I am starting to notice a vision issue in one eye, but I don’t know if it’s related. I’m getting ready to see an ophthalmologist. I’m also in my 50s and knew already that I have the beginnings of cataracts. At first, injections cause constipation, eating better causes them to become regular for me."
- Fay...
- Taken for less than 1 month
- January 22, 2025
For Weight Loss (Obesity/Overweight) "I started Wegovy 2 weeks ago. I have acid reflux and constipation. I took 1 magnesium/citrate gummy to help with the constipation and ended up with severe cramping with diarrhea in the middle of the night. The acid reflux happens every evening, and acid reflux meds cause constipation. I’m not enjoying the Wegovy."
More FAQ
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- Jol...
- Taken for 1 to 6 months
- November 24, 2024
For Weight Loss (Obesity/Overweight) "I started on Wegovy .25 mg mid-August and felt no side effects but no weight loss neither. Difficult stool movement right away. After 6 weeks, I started taking .50 mg after difficulty finding this dose in any pharmacy in Miami. I stayed on this dose for 4 weeks without any weight loss or bad side effects, other than constipation. Then I started taking 1 mg and immediately started feeling very bad: severe nausea and indigestion and bad diarrhea. Obviously, you can’t eat anything, so yes, I finally started losing weight, but felt so bad, I could not function, slept a lot, did not eat, was on the toilet a lot, and decided this was not worth it and stopped after two injections. Perhaps other people can deal with these kinds of side effects or they just react easier. Since I started on low doses for so long, I was disappointed the side effects were still so strong. After about three days (after stopping), I feel normal again but weight comes back quickly if you don’t have an iron will!"
- KM2...
- Taken for 6 months to 1 year
- March 11, 2025
For Weight Loss (Obesity/Overweight) "Have lost about 10 lbs over the last 7 months, but I had lost 30 already using a behavioral modification weight loss plan and was stuck. Doctor moved me up in doses very slowly to help me maintain lose in the long run. I am happy with this approach. Insurance covers this for me as I have high blood pressure, high cholesterol, and both parents have/had heart disease, and one parent already passed due to a heart attack and the other has already had two. My goal is to lose another 20 or so pounds and keep it off. Hoping to be able to step down the dose for maintenance. Biggest side effect has been constipation, but using OTC laxative at night and that keeps everything moving. Game-changing drug, especially having it covered by insurance."
- Ano...
- Taken for 1 to 6 months
- August 4, 2025
For Weight Loss (Obesity/Overweight) "I'm starting week 7 on Wednesday of this week of 0.5 mg. I've only lost 11 pounds. Have experienced a lot of headaches, reflux, and constipation. I'm taking a women's +50 multivitamin, 400 mg of magnesium glycinate, and a probiotic as suggested by my doctor."
- Anonymous
- Taken for 1 to 6 months
- May 3, 2023
For Weight Loss (Obesity/Overweight) "My experience so far is positive: 21 lbs down in 8 weeks. First, 4 weeks on .25 mg was great, no side effects. Weeks 5 and 6 were also good, slightly uncomfortable stomach but not bad, weeks 7 and 8, with 7 being not so bad. Then week 8, I had more stomach pain for a few days and didn’t have much of an appetite. Constipation is a real thing on this medication. Also, I am having a fast heart rate and seem to be a slight case of anxiety. Although I am experiencing some side effects, I am not giving up yet. I think for me, staying on a lower dose might be best. The .25 mg does work with fewer issues."
- WmB...
- Taken for less than 1 month
- June 13, 2023
For Weight Loss (Obesity/Overweight) "Wegovy hasn't resulted in any weight loss. At times, I'm nauseous, full, and constipated regularly. Also, the injection device failed to work, no clicks or moving yellow bar. The product failed to go in and leaked all over, thereby causing me to get no shot/dosage."
- Sli...
- Taken for 1 to 6 months
- April 1, 2022
For Weight Loss (Obesity/Overweight) "So I am 5'4" and I found myself at the weight I was when I delivered my children, 145 pounds. For three years plus, I desperately tried to approach my goal weight of 125 pounds, dieting and feeling miserable for 3 years. I told my doctor I was dieting and exercising and could not budge the scale. At 60 years of age, the weight just doesn’t come off like when you are young. I’ve been on Wegovy for 6 weeks and have lost 12 pounds-a miracle! Now at 133 pounds, I’m staying the course to my goal. I will say the nausea is the worst side effect and comes in intermittent waves. I have Zofran (ondansetron) for when I can’t take the nausea. One of the best side effects for me has been totally eradicating my diarrhea. I have irritable bowel on the diarrhea spectrum, and luckily I did not get the diarrhea side effect but more the constipation, which has totally normalized my GI tract! I am so happy about this and assume this is due to slowing gastrointestinal motility."
- Chr...
- Taken for 1 to 6 months
- March 28, 2022
For Weight Loss (Obesity/Overweight) "I started on Wegovy in December 2021. In the beginning, it made me sick to my stomach. I had the belching and very little appetite. When I got to 0.50 mg, oh my God! I could hardly eat anything for a couple of days. I was scared to go to the next level, but I did. When I was on the 1 mg dose, I didn't have any issues. Once I got to 1.7 mg, it wasn't bad either- a little belching, headaches for a couple of days, upset stomach, and constipation kicked in. Getting ready to start the maintenance level of 2.4 mg, and let's pray I tolerate it well. So far, I have only lost about 27 lbs, trying to lose about 17 more to get to my ideal weight. This is the best medicine that has helped me lose and, prayerfully, keep it off. I have learned how to eat small meals and make better choices in foods."
- Ano...
- Taken for 1 to 6 months
- May 7, 2025
For Weight Loss (Obesity/Overweight) "I have done very well with Wegovy. I am now on the highest dose. This is the 3rd week on the highest dose, and I have lost 25 lbs in 4 months, and I am still losing. I have had some common issues such as nausea, diarrhea in the first month, but that went away. Then in the 2nd month, I had minor stomach pain, and the diarrhea changed to constipation. I am still experiencing constipation but managing it with fiber. Other than these issues, I am happy with the medication, and I feel so much better!"
- Ano...
- Taken for 6 months to 1 year
- July 14, 2025
For Weight Loss (Obesity/Overweight) "Switched to Wegovy because insurance would no longer cover Mounjaro. After a year of slow and steady decline in weight on Mounjaro with little to no side effects, Wegovy stalled my progress. I lost nothing, felt nauseous, was constipated, and burpy. It reintroduced cravings for foods I had little interest in during Mounjaro. I was hungry (peckish) most of the day. I regained 5 lbs in 6 months, reversing my previous downtrend. I was on the max dose. I have friends who, at the same time, were successful in losing weight."
- Tin...
- Taken for 1 to 6 months
- March 8, 2023
For Weight Loss (Obesity/Overweight) "Been on Wegovy 0.25 mg for 6 weeks now and have lost 15 pounds. I have had side effects of nausea after injection for about 24 hours and constipation, which is resolved with laxatives. Wegovy curbs your appetite and has changed the taste of certain foods for me. I am increasing the dosage to 0.50 mg to see if weight loss is quicker."
- Ano...
- Taken for 1 to 6 months
- April 9, 2025
For Weight Loss (Obesity/Overweight) "No adverse side effects. Just took 8th injection and last at 0.5 mg. Next week, dosage goes to 1 mg. Down 16 pounds in 7 weeks. I was already taking Metamucil every morning, so no constipation as some have reported, but I am having less bowel movements now. I imagine I would be constipated without it. Also take Nexium daily, so heartburn really hasn't been an issue more than it already was. Started at 6 ft and 251 pounds. Was 235 today. Goal is between 180 and 200."
- Fay...
- Taken for 6 months to 1 year
- July 7, 2025
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 6 months. I am on the highest dosage now. It has not been a pleasant journey. I feel sick probably half the time. The worst side effect for me is constipation. I poop every 4th or 5th day. I get horrible cramps. I have only vomited 3 or 4 times. I’m waiting for the side effects to go away. I am going to stay on it for a year and re-evaluate if the side effects are worth it. I have never had chemotherapy, but I think this has similar side effects. I have lost 1 pound a week, so about 28 lbs."
- Jam...
- Taken for 1 to 6 months
- February 2, 2022
For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy (Ozempic) for 10 weeks, first at 0.25 mg and now on 0.5 mg. I have not lost any weight (but not gained any). It has not curbed my appetite, and I still crave sweet stuff. I have had a few side effects, but the worst is constipation, and I have not had a normal poo since I started. I also have a headache, get dizzy if I stand up quickly, and my hair is falling out somewhat. I eat high fiber and take psyllium husk, and still no poo in a week sometimes. I would stay on it at higher doses, but the cost of £155 per month is not worth it if no effect so far. Disappointed because so many have a good result with this medication."
- car...
- Taken for 1 to 6 months
- February 21, 2022
For Weight Loss (Obesity/Overweight) "I have been on Wegovy since October 2021. I'm currently on 2.4. I have lost a total of 35 pounds. I have a lot of constipation, I have to take something for the constipation. I do have some vomiting when I eat hot, spicy, or greasy food. I'm very pleased with Wegovy."
- big...
- Taken for 1 to 6 months
- May 27, 2024
For Weight Loss (Obesity/Overweight) "This is the first week at the 1mg dose, I lost 8 pounds last week. Before this, I was too scared to get on the scales, but I can feel I have lost significant weight. I have reduced appetite and cravings for sweet things that started almost immediately upon starting the drug. The only side effects I have had were, around week 3, constipation and trapped wind that caused waves of stomach pain for a few days. In the UK, you are supposed to be able to get this on the NHS if your BMI is over a certain level with associated health issues. However, no funding has been provided, so I am paying around £150-200 per month. This is offset by reduced food costs and alcohol costs that make it almost pay for itself."
- Hop...
- Taken for 1 to 6 months
- April 22, 2022
For Weight Loss (Obesity/Overweight) "I started on Ozempic 12 weeks ago in Jan 2022, which is the same as Wegovy in a lower dosage. I spent 4 weeks on the 0.25 dosage, losing 2 lbs. Moved up to the 0.5 dosage for 4 weeks, losing another 2 lbs, moved up to the 1 dosage for 4 weeks, and lost an additional 3 lbs. I just took my first dose of Wegovy at the 1.7 dosage, and wow can I tell a difference. I won’t lie, I have experienced a few side effects, such as constipation, some abdominal pain, nausea, headache, and diarrhea, but all have been mostly mild and very tolerable. Nothing that can’t be helped with eating a little less. The key to managing all of it is learning how to eat properly with the right portion sizes. Only eat until you are satisfied rather than full. For me, it is well worth dealing with mild side effects in order to achieve a healthy lifestyle!"
- yir...
- Taken for less than 1 month
- May 2, 2023
For Weight Loss (Obesity/Overweight) "I started Wegovy .25 mg on March 5th. On day 1, I felt a little nausea and a little tired. Felt fine the rest of the week, appetite suppressed after a day or so. Continued to follow a healthy diet, exercised at least 5 days a week, and meal portions became smaller. I did not experience any other side effects aside from a little heartburn at night after the 2nd dose. By the 3rd dose, I started feeling somewhat constipated and noticed my watch was notifying me more frequently than usual that my heart rate was over 100 throughout the day and night. I take blood pressure medication, so I decided to call my doctor. She does want me to get blood work done and will be checking my thyroid. Also recommended I stop taking the med. I am a bit worried as I already feel the cravings are coming back. After I complete blood work, I will provide additional feedback regarding recommendations from my PCP. I have lost about 14 lbs., so it does work. I would give it a shot, everyone reacts differently."
- KRI...
- Taken for less than 1 month
- March 22, 2023
For Weight Loss (Obesity/Overweight) "Wegovy for weight loss. On my first injection. 0.25 mg dose. I felt a bit of nausea, but it went away, and I was constipated. However, within 4 days, I had lost 4 pounds. I feel great, it also curbs my cravings for food and wine, and I am sleeping better. So far, so good!!"
See also:
More about Wegovy (semaglutide)
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- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
For Weight Loss (Obesity/Overweight) "I've been taking Wegovy since September (2024). I initially did not like the way it made me feel. I was experiencing constipation, headaches, and nausea. My next dose was 0.50, which the pharmacy was out of until this past April 2025. I was determined to see if I could withstand the side effects. My appetite was suppressed immediately. I experienced constipation, which I counteracted with stool softeners every day. I took Zofran for the nausea. I had started riding my stationary bike around the same time that I started Wegovy. On April 17th, 2025, I started walking 30 minutes a day. I am now at a 1.7 dose. Side effects are minimal. I noticed that if I am constipated, I would get nauseous. Stay away from heavy grease. I consume a protein shake every morning and try to eat meat as much as I can as I do not really have a taste for meat or I no longer like alcohol. I am happy that I tried it again. I am 6'1" and was 283. I am 266. I want to be 240. Yay!"