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Comparing Azithromycin vs Minocycline

View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Azithromycin Remove Azithromycin from your drug comparison Minocycline Remove Minocycline from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Azithromycin Remove Azithromycin from your drug comparison Minocycline Remove Minocycline from your drug comparison

Azithromycin is an antibiotic used to treat a variety of different infections. It has the distinct advantage of once-daily dosing; however, diarrhea is a common side effect. Prescribed for Bacterial... View more

Prescribed for Bacterial Infection, Acne, Bartonellosis, Actinomycosis, Bullous Pemphigoid, Plague, Skin or Soft Tissue Infection, Skin and Structure Infection, Rabbit Fever, Q Fever, Psittacosis,... View more

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews
7.1
1004 Reviews

For Chlamydia Infection: First time I took azithromycin no problems at all. Second time my stomach felt like I was super hungry for a while and I had diarrhea for about an hour after I took it. My partner and I have been very itchy though even after a week and not sure when this should end. Not sure if my symptoms even went away yet so I'm still skeptical about having sex, but overall the drug seems effective and helpful.

8

For Chlamydia Infection: First time ever having an STI, short story short thought me and the guy where exclusive ahh how wrong was I! Anyways I went to my GP today after he told me he tested positive, took Azithromycin two tablets at once at about 5 o'clock and an hour later my stomach made me feel like I'm gunna hurl but I'm trying my best to not throw up because I am not going through this again.. 7/10 for me at the end of the day it gets rid of this horrible bacteria living in my vaj, just take it while you're at home because I feel like the devil is trying to dance in my stomach. Good luck guys, I'm gunna go lie down and abstain from sex til I'm 30.

8
6.3
461 Reviews

For Acne: I'm a healthy 25 year old female who's been on minocycline for about 3-4 months now. It's worked wonders and I didn't have any side effects to it, until now. About two weeks ago, I had this awful abdominal pain that landed me in the ER for fear it was my appendix. Everything came back perfect. I've since cut back on my antibiotic and only take it every other day because through process of elimination, I think it's the culprit to my abdominal pain. My PCP told my I may have developed acute IBS or irritable bowel syndrome from the minocycline (since it is an anti-biotic and will get rid of normal flora). I'm very upset that I have to stop it; I rarely use any cover up now because my skin is so clear.

7

For Acne: Minocycline 100mg did work for me. For the very first month, I noticed my skin getting worst, but I decided to give it another month which was right decision. Now after 2 months my skin is clear and I'm quite happy with the results

7

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View all 461 reviews

Drug Class

Side Effects

Commonly reported side effects include: diarrhea, loose stools, and nausea.

See the full azithromycin side effects document.

Commonly reported side effects include: headache.

See the full minocycline side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 2 tablet
Dosage 250 mg
Per Unit* $5.84
Cost* $11.68

View all azithromycin prices

Quantity 7 capsule
Dosage 100 mg
Per Unit* $1.31
Cost* $9.15

View all minocycline prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Intravenous powder for injection
  • Oral powder for reconstitution
  • Oral tablet
  • Oral capsule
  • Oral tablet
  • Oral tablet, extended release

Brand Names
Azithromycin Dose Pack, Z-Pak, Zithromax, Zmax Cleeravue-M, Dynacin, Minocin, Minocin for Injection, Minolira, Myrac, Solodyn, Ximino

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

53 hours

17.9 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (3)

N/A

Drug Interactions

A total of 446 drugs are known to interact with azithromycin:

  • 70 major drug interactions (183 brand and generic names)
  • 342 moderate drug interactions (1691 brand and generic names)
  • 34 minor drug interactions (123 brand and generic names)

A total of 347 drugs are known to interact with minocycline:

  • 13 major drug interactions (38 brand and generic names)
  • 264 moderate drug interactions (2511 brand and generic names)
  • 70 minor drug interactions (232 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.

Disease Interactions

First Approval Date

November 01, 1991

June 30, 1971

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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