Comparing Amphetamine vs Modafinil
| Amphetamine | Modafinil |
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| Amphetamine | Modafinil |
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Prescription only
Prescribed for ADHD, Narcolepsy, Weight Loss (Obesity/Overweight). Amphetamine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Depression, Fatigue, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
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| More about Amphetamine | More about Modafinil | ||||||||
| Ratings & Reviews | |||||||||
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Amphetamine has an average rating of 6.5 out of 10 from a total of 141 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Amphetamine side effects |
View all Modafinil side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Modafinil prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Adzenys ER, Adzenys XR-ODT, Dyanavel XR, Evekeo, Evekeo ODT | Provigil | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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17 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 220 drugs are known to interact with Amphetamine:
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A total of 521 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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August 31, 1984 |
December 24, 1998 |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Amphetamine/dextroamphetamine
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.