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Amphetamine and Headaches: What Users Say

Brand names: Adzenys XR-ODT, Dyanavel XR, Evekeo, Adzenys ER, Evekeo ODT

Headaches: mentioned by 7 users (5.0%)

Based on user experiences from 141 Amphetamine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 10.6%
insomnia 10.6%
loss of appetite 7.1%
irritability 6.4%
depression 5.7%
mood swings 5.7%
headaches 5.0%
tiredness 5.0%
brain fog 4.3%
dry mouth 4.3%

Reviews for Amphetamine

Commonly mentioned side effects
  • Cal...
  • Taken for 1 to 6 months
  • October 12, 2016

Amphetamine for ADHD "The only ADHD medication I have taken that doesn't have awful side effects. It makes you more alert and productive without the headaches and hungover feeling that I get with Adderall and Focalin. I don't think it affects everyone the same, but it has been a real lifesaver for me."

9 / 10
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34 Report
  • Und...
  • Taken for less than 1 month
  • October 11, 2018

Amphetamine for ADHD "I just recently had to switch doctors because I moved states. Well, she switched my meds. I was on Adderall XR. It worked really well for me, but she insisted this new medication would be much better. I have now been on Adzenys for one week, and I’m miserable. I have a migraine-like headache, and I haven’t slept more than 3 hours at a time. I will be putting in a call tomorrow for my old Adderall."

5 / 10
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19 Report
  • Bea...
  • Taken for 6 months to 1 year
  • March 28, 2018

Amphetamine for ADHD "I was very disappointed with varying generics of Adderall XR for my combined ADHD. Brand was better but caused some side effects. Adzenys ODT is a million times better than either. I think my body doesn't respond well to amphetamine salts (Adderall) but does to amphetamine base (Adzenys). Or maybe some of the inactive ingredients that are artificial sweeteners in Adderall (aspartame, for example) are reacting badly; I know I can't eat or drink any foods with aspartame or saccharin without getting headaches and low blood sugar, but this would still not explain why the active amphetamine in Adzenys works so much better for me, so I'm going to have to go with the salt vs. base hypothesis. Adzenys doesn't make me sleepy like Adderall XR/IR, feels cleaner and smoother, works better for ADHD symptoms like impatience, impulsivity, procrastination, avolition, and task initiation and completion. I just wish there was an Adzenys IR."

10 / 10
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17 Report

Frequently asked questions

  • Din...
  • Taken for less than 1 month
  • June 6, 2019

Amphetamine for ADHD "Having a high metabolism, my medications wear off very quickly. Dr. and I talked about trying Evekeo, but decided to try adding one more dose of Adderall XR to the mix. When that didn’t help, I tried Evekeo and discontinued the Adderall XR but kept the afternoon doses of IR. As for Evekeo, I had a very bad reaction to it. My face broke out, and not pimples but sores that are now going to scar. My depression (which I haven’t had in a while due to the consistency of taking medication) was three times worse, I went to a very dark place. I went days without sleeping, no motivation or drive to do anything, very irritable, very mean, not social at all, terrible intrusive thinking, pushed away anyone that was close to me, no appetite at all, headaches, muscle soreness, and vomiting/diarrhea. Thankfully, we stopped the medication, but I don’t want to feel like this ever again!"

1 / 10
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13 Report
  • Mel...
  • Taken for less than 1 month
  • October 3, 2018

Amphetamine for ADHD "My doctor suggested switching me from 70 mg of Vyvanse to 10 mg of Evekeo (2x per day) to see if that eliminated the insomnia issue I was having with Vyvanse. After a week on Evekeo, I'd go back to Vyvanse in a heartbeat. I've been taking stimulant medication for ADD for almost 30 years, and I have never had one be utterly ineffective at helping me focus. With Evekeo, it's like I took nothing at all. Zero ability to focus. To make matters worse, I'm experiencing 6 of the main side effects, one of which is a raging headache that sticks around all day (and feels like a migraine when the med first kicks in). It makes me feel very wired and shaky, too. I just called my doctor and asked to be squeezed in ASAP so I can switch to something else (might go back to Adderall), as I cannot keep taking Evekeo for another 20+ days."

2 / 10
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10 Report

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  • adu...
  • January 30, 2017

Amphetamine for ADHD "Adderall XR became less effective, so the doctor wanted me to try Adzenys XR 15.7. I do not like it. Terrible headaches right after I take it, then I get nauseated. Even though the Adderall XR has become less effective, at least it gives me some concentration without side effects. Also, I hate the blister pack it comes in, and it tastes terrible with a gritty bad aftertaste."

1 / 10
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14 Report
  • Mil...
  • Taken for less than 1 month
  • July 11, 2021

For ADHD "This has been an awful experience! I take Adderall normally. The doctor forgot to add something to my script and got this. I didn't think it would be different. It for sure is. Headaches, stomach aches, and I have no attention span for a week now. I just messaged my doctor after talking to the pharmacist. I guess this is often a complaint. I feel really bad for people whose insurance won't cover the real stuff. Should be illegal to give this to people just because they can't afford better insurance."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.