Amphetamine Alternatives Compared
| Amphetamine | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Lumryz (sodium oxybate) |
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| Amphetamine | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Lumryz (sodium oxybate) |
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Prescription only
Prescribed for ADHD, Weight Loss (Obesity/Overweight), Narcolepsy. Amphetamine may also be used for purposes not listed in this medication guide. |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Prescribed for Idiopathic Hypersomnia, Narcolepsy, Cataplexy. Lumryz may also be used for purposes not listed in this medication guide. |
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| More about Amphetamine | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Lumryz (sodium oxybate) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Amphetamine has an average rating of 6.5 out of 10 from a total of 140 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
Lumryz has an average rating of 8.5 out of 10 from a total of 6 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Xywav prices |
View all Lumryz prices |
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| Dosage Forms Available | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Adzenys ER, Adzenys XR-ODT, Dyanavel XR, Evekeo, Evekeo ODT |
N/A |
Other sodium oxybate brands include: Xyrem | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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17 hours |
0.66 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 220 drugs are known to interact with Amphetamine:
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A total of 346 drugs are known to interact with Xywav:
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A total of 346 drugs are known to interact with Lumryz:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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August 31, 1984 |
July 21, 2020 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.