Comparing Amitriptyline vs Imipramine
| Amitriptyline | Imipramine |
|
|---|
| Amitriptyline | Imipramine |
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Prescription only
Prescribed for Enuresis, Pain, Interstitial Cystitis, Primary Nocturnal Enuresis, ADHD, Depression, Irritable Bowel Syndrome, Night Terrors, Panic Disorder, Somatoform Pain Disorder. Imipramine may... View more |
Related suggestions Depression
Irritable Bowel Syndrome
Interstitial Cystitis
|
|||||||||||||||
| More about Amitriptyline | More about Imipramine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
|
Amitriptyline has an average rating of 7.6 out of 10 from a total of 1810 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Imipramine has an average rating of 7.3 out of 10 from a total of 79 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
||||||||||||||||
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amitriptyline side effects |
View all Imipramine side effects |
||||||||||||||||
| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
|
Lower cost generic |
Lower cost generic |
||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amitriptyline prices |
View all Imipramine prices |
||||||||||||||||
| Dosage Forms | |||||||||||||||||
|
|
||||||||||||||||
| Brand Names | |||||||||||||||||
|
N/A |
Tofranil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
|
16 hours |
20 hours |
||||||||||||||||
| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
| Pregnancy Category | |||||||||||||||||
|
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
||||||||||||||||
| Drug Interactions | |||||||||||||||||
|
A total of 717 drugs are known to interact with Amitriptyline:
|
A total of 739 drugs are known to interact with Imipramine:
|
||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
|
|
||||||||||||||||
| Disease Interactions | |||||||||||||||||
|
|
||||||||||||||||
| First Approval Date | |||||||||||||||||
|
April 07, 1961 |
April 16, 1959 |
||||||||||||||||
| WADA Class View classifications | |||||||||||||||||
|
N/A |
N/A |
||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
|
|||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Qulipta
Qulipta is used to help prevent episodic or chronic migraine headaches in adults. Qulipta is an ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Tylenol
Tylenol is a pain reliever and a fever reducer used to treat many conditions such as headaches ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Oxycodone
Oxycodone is an opioid analgesic used to treat moderate to severe pain; it has a high potential for ...
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug used to treat pain and inflammation associated ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.