Semaglutide and Constipation: What Users Say (Page 5)
Brand names: Ozempic, Rybelsus, Wegovy
Reviews for Semaglutide
- Mel...
- Taken for 6 months to 1 year
- November 26, 2020
Semaglutide for Cardiovascular Risk Reduction "I have been on Ozempic 7 months and have lost 48 pounds and counting. I tapered up to 1 mg after 6 months. The only side effect is constipation is worse."
- Isa...
- Taken for 1 to 6 months
- September 24, 2020
Semaglutide for Type 2 Diabetes "My endocrinologist prescribed 3 mg to start because the B12 depletion from metformin (I have B12 anemia) was not good and constant yeast infections from Forxiga were very annoying. At first, I noticed a major appetite decline. There was a bit of nausea for the first 2 weeks. I started the 7 mg after a month and while I've been experiencing constipation, I am so happy about the weight loss. I've been on Rybelsus for 10 weeks and have lost 10 lbs. My latest random glucose test had me at 5.7, down from 6.3 - 7 over the previous few months. I am happy about fewer carb cravings and will stay on Rybelsus as long as I can. I am lucky my health plan covers it because it's quite expensive."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Why am I not losing weight on Ozempic?
- Ski...
- Taken for 1 to 6 months
- May 31, 2020
Semaglutide for Type 2 Diabetes "My husband began taking Ozempic for his Type 2 diabetes several months ago and experienced minimal unpleasant side effects. His food consumption is down approximately 2/3 (no more 'first breakfast and second breakfast' and 'first dinner and second dinner') and he has been able to reduce his diabetes medications. He has been steadily losing excess weight. A bonus is the chronic loose stools he used to suffer have been eliminated. I started taking Ozempic for my Type 2 diabetes 6 weeks ago. My food consumption is down significantly and I've been able to discontinue all other diabetes medications. I've had some slight nausea and a mild bit of constipation, both of which have been easily alleviated through dietary changes (much smaller meals, more fiber and more spicy food). We absolutely love this medication."
- Ano...
- Taken for 1 to 6 months
- May 19, 2020
Semaglutide for Type 2 Diabetes "I was terrified to take this after reading some of the reviews online, but I have to say I am so happy I started this drug. I've followed others' suggestions about injecting the drug into my upper thigh and not my abdomen. I was on a 0.25 dose for 4 weeks, then moved to 0.5, and that's what I currently take. My appetite has decreased SIGNIFICANTLY. I was addicted to eating junk foods, and I simply cannot eat them anymore, my stomach cannot handle them. I get full after eating one properly sized meal, and it keeps me going for most of the day, only having a snack like 1 apple in the evening. Side effects were mild for me, I had some constipation, but I started taking fiber supplements to help with that. I have been on the medication for 7 weeks now, and I'm down 10 lbs, and I feel great. Make sure your doctor gets you to increase the dose slowly, inject into your thigh, and be ready to make better dietary choices when starting this drug. I truly believe it saved me from morbid obesity."
Are you taking this medicine?
Your review helps others make informed decisions.- Ret...
- Taken for 1 to 6 months
- February 25, 2020
Semaglutide for Type 2 Diabetes "Take my comments for what they are worth since I changed many things in my life at the same time, but I think Ozempic is great. After 5 months, it reduced my A1c from 9.7 to 5.9. I lost almost 25 pounds. I am at 0.5mg, and it has drastically reduced my appetite. Between a smaller stomach and this drug, I often push my plate away before finishing, rarely a desire for dessert. Little to no side effects overall. Some stomach issues like constipation and bloating, but I can't rule out dietary changes being the cause as well. I went on a low-carb diet and really stuck to it for once and increased exercise a lot. The use of the Freestyle Libre Sensor really helped too! Being able to learn how things affect your blood sugar in real time is a great motivator to do the right thing, combine carbs with protein, etc. I am hoping to lower other meds I am on when I see my doctor next month. Once a week, a tiny needle (virtually pain-free) is a far better system than taking pills every day."
- Anonymous
- February 7, 2020
Semaglutide for Type 2 Diabetes "My doctor put me on Ozempic to lower my blood sugar and A1c, as every time I check my blood sugar it’s extremely high in the 200s and 300s. So that is why my doctor put me on Ozempic. At the beginning of the year, before the medication, my A1c was 10.8, and my blood sugar was in the 200s. Five weeks later, I went to the doctor this week and got my sugar checked, it was 72. I couldn’t believe it, plus my A1c is 8.2, and I lost 5 lbs in just a short period. I take my shot every Sunday, .25. The day after I take the shot, I do experience some nausea, headaches, and constipation, but it’s only for one day, and it’s worth it for these low numbers. I was scared to take this new drug because I already take metformin 1000 mg once a day, but I’m so happy my doctor introduced me to this medicine. If you guys can get through the side effects, keep taking it, this medicine really works."
More FAQ
- How does semaglutide work for weight loss?
- How much does semaglutide cost?
- Where and how should Ozempic be injected?
- Does Ozempic cause muscle loss and how to prevent it?
- Bea...
- October 14, 2019
Semaglutide for Type 2 Diabetes "I started Ozempic at the end of July 2019. After 10 years of Metformin 1000 mg a.m. and p.m. & Januvia, the result turned into explosive diarrhea. Tried Jardiance, which resulted in yeast infections. Then Janumet, all of these with Metformin. Constipation. Started Ozempic in July, 0.5 mg with Metformin. Lost weight and appetite suppressed, but diarrhea continued. Changed to 1000 mg Metformin in a.m. & Januvia in p.m. Constipation again. Changed to 1 mg Ozempic after several months and 1000 mg Metformin in a.m. and 500 mg p.m., no Januvia. Constipation. Finally taking 1 mg Ozempic and 750 mg Metformin a.m. and p.m. works great. Bowel movements normal. My daily readings went down using Ozempic. No side effects. Lost 19 lbs. Not due for A1C until December. Love it. Went from 200 lbs to 181. Sugar cravings decreased. Feel positive. I am an active 70-year-old female. I don’t plan on taking Ozempic forever because the possible long-term thyroid side effects scare me."
- Ste...
- June 7, 2019
Semaglutide for Type 2 Diabetes "I'm a 47-year-old African American who has battled with diabetes for over 25 years. In 2012, I had the gastric sleeve surgery. I started off at 268 lbs, after surgery, I went down to 207 lbs. I also have severe retina disease, for which I have to get laser treatments every month. So my doctor was like, try this medicine called Ozempic. I was extremely cautious and read up on the reviews. I started on a 0.5 dosage around February 2019 and dropped down from 228 lbs to 215 lbs. I was a little nauseous the first week, but it went away. Currently, I'm on a 1.0 dosage a week, down to 197 lbs as of June 5, 2019. My A1C is 6.3, however, I had to have another treatment on my eyes because the bleeding hasn't stopped. I'm so happy with Ozempic. However, I am losing weight so fast, it makes me nervous. Then being a gastric sleeve recipient helps even more to my advantage. I do experience constipation a lot. I'm not hungry, but I do feel tired during the middle of the day."
- Tme...
- May 26, 2019
Semaglutide for Type 2 Diabetes "I love this medication. I've been on the med since 3/8/2019. 11 weeks. I have lost 27 pounds and feeling good. I have learned to switch the spot where I give the shots. I find when I give them in the stomach only, I get constipated. And the day after giving the shot, I get a headache. I sleep with two bottles of water by my bed daily. If I don’t drink it at night, in the morning I do."
- Sup...
- Taken for less than 1 month
- April 15, 2025
For Weight Loss (Obesity/Overweight) "Almost 2 weeks into semaglutide (0.25 mg) and I am down 10 lbs. It basically makes me less hungry, which facilitates cutting out the unhealthy foods I crave, including sugar. I went low carb (essentially keto) from the start, and the side effects have been minimal. I feel full after a small meal and don't have the urge to eat before bed. The only real side effect to note is the bloating the day after the shot. But if you buy Gas-X, it basically fixes that issue. I saw a lot of folks saying the injections in the stomach reduce the side effects, but I wonder if it also reduces the effectiveness of the injection. The shot basically slows your digestion down, which can lead to constipation, but if you drink a lot of water, it should offset that."
- KM2...
- Taken for 6 months to 1 year
- March 11, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "Have lost about 10 lbs over the last 7 months, but I had lost 30 already using a behavioral modification weight loss plan and was stuck. Doctor moved me up in doses very slowly to help me maintain lose in the long run. I am happy with this approach. Insurance covers this for me as I have high blood pressure, high cholesterol, and both parents have/had heart disease, and one parent already passed due to a heart attack and the other has already had two. My goal is to lose another 20 or so pounds and keep it off. Hoping to be able to step down the dose for maintenance. Biggest side effect has been constipation, but using OTC laxative at night and that keeps everything moving. Game-changing drug, especially having it covered by insurance."
- Wor...
- Taken for 6 months to 1 year
- February 25, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "Beginning weight was 234 and began at 0.25 in June 2024, and just began 2.4 today at 177. Been going up very slowly, but weight loss has slowed way down. Still have 17 pounds to lose, but prefer 27 more. Have gone from 2XL/Size 22 to size 14. Have dealt with nausea, headaches, occasional constipation/diarrhea, depending on what I eat. Small meals, five times a day, plus drinking lots of water is key. I get extremely tired the day or two after taking the shot. I take the shot at night, hoping to be at my goal weight by the end of May 2025. 63-year-old woman and all blood work now within normal limits."
- Suz...
- Taken for 1 to 2 years
- February 20, 2025
Semaglutide for Type 2 Diabetes "Lower doses caused constipation, at the highest dose of 2, I experienced a full day of being sick to my stomach after injection. On these days, I ate saltine crackers and drank Coke Zero. The following days, I felt bloated and experienced burping and gas. However, I continued to lose weight, and my A1c was down to 7.6."
- Kar...
- Taken for 6 months to 1 year
- February 19, 2025
Semaglutide for Type 2 Diabetes "I have been using for 10 months proximately (0.5 mg). It has steadied glucose with less insulin (Lantus), and I have lost about 25 lb (started at 302 lb). I would like a higher dosage to help with the weight issue, as it's been very helpful with appetite reduction. The doctor has not raised it for fear of hypoglycemia issues. I've had no real side effects beyond occasional nausea and constipation. Slower movement through the gastrointestinal system gives me a rather hard-packed stool. I have consistently had flatulence since week one."
- M S...
- Taken for 6 months to 1 year
- January 14, 2025
Semaglutide "Ozempic has helped in my weight loss. 14 pounds in 4 months, slower loss after. Sense of fullness. Have had constipation, 3 or 4 days without going to the bathroom. Use medication and it does work."
- Ros...
- Taken for 1 to 2 years
- January 10, 2025
Semaglutide for Cardiovascular Risk Reduction "35 lbs weight loss. A1C went from 5.7 to 5.2. Triglycerides now WNL. Triglycerides were high prior to Ozempic, even on a statin. Cholesterol (HDL and LDL) WNL. HDL was low and LDL high prior to Ozempic. Experienced moderate constipation, treated well with Senokot. Minor nausea at times. Belching if ate too fast."
- Rem...
- Taken for 1 to 6 months
- January 3, 2025
Semaglutide for Weight Loss (Obesity/Overweight) "Other medications I am required to take have caused increased appetite and subsequently weight gain. Almost immediately after starting Wegovy (0.5), I wasn't hungry, was not craving carbs or sweets, and was able to eat good food and be satisfied with less than half the amount of food I usually had. In seven weeks, I have lost 9 kilos. It seems effortless after years of dieting. Side effects are definitely constipation and dehydration. I did have a problem with the pen on week 4, wasn't sure I got the dosage, but seems ok so far."
- mat...
- Taken for 6 months to 1 year
- December 4, 2024
Semaglutide for Type 2 Diabetes "It seems to be helping me with my diabetes. My levels have been lower. My side effects are constipation, burping, nausea."
- Dus...
- Taken for 1 to 6 months
- December 2, 2024
Semaglutide for Weight Loss (Obesity/Overweight) "Weight loss from the start, but severe constipation. Relieved by MiraLAX. Some stomach pain from time to time."
- Jos...
- Taken for 1 to 6 months
- November 14, 2024
Semaglutide for Type 2 Diabetes "I'm on 14 mg a day, since July, and now I'm experiencing pain in my upper thigh after my morning dosage. It's been for about 2 weeks now. I've also experienced some constipation. Other than that, I have no problem with this medication. Hopefully, we can find out what's with these side effects."
- Mac...
- Taken for 1 to 6 months
- November 11, 2024
Semaglutide for Type 2 Diabetes "1. Very good to date with stabilizing my glucose levels. 2. Unpleasant gastric conditions, i.e., bloating, burping, farting, constipation. 3. I'm taking 0.5 mg weekly and finding it very, very difficult to maintain a regular supply of the 0.025 to 0.5 mg dosage."
- Jen...
- Taken for 1 to 2 years
- October 22, 2024
For Weight Loss (Obesity/Overweight) "I started taking semaglutide in April of 2023 and was at my highest weight ever (230 lb) and perimenopausal. I have never really struggled with weight gain until my 40s, and when I hit 230, I was seriously considering if I would be a candidate for bariatric surgery, but thankfully someone suggested semaglutide. I did experience side effects-nausea, headache, some constipation-but I have lost 70 lbs, and I think taking semaglutide was worth it."
- Oze...
- Taken for 6 months to 1 year
- October 4, 2024
For Type 2 Diabetes "Lost 10 pounds. A1C reduced from 7.6 to 6. Experienced side effects: stomach pain, constipation, diarrhea."
- hum...
- Taken for 1 to 6 months
- September 3, 2024
Semaglutide for Type 2 Diabetes "My A1C's have dropped, and I have so far dropped 28 lbs in 4 months. I feel much better physically and mentally. I started out at 0.25 and am up to 0.5 mg. I did have an upset stomach and constipation, but it's not as bad now. My body must be getting used to it."
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Semaglutide for Type 2 Diabetes "I have been on Ozempic for about a month, and the only problem I have is constipation, and I take stuff for it. I love my blood sugar level, it never reaches the 200 and higher range, and I love how I can't eat much anymore because before Ozempic, I would eat, but after each meal, I still would be hungry and eat some more. But since Ozempic, I can't eat a whole lot. My meal portion really went down. I no longer can eat a whole chicken breast, half of one with a small serving of cooked vegetables, and if we have a T-bone steak, half or even smaller size, I cut off and eat the rest the following day as two meals. I've lost already 15 lbs, and I feel wonderful, and I have energy again too. Can't wait to see what my A1C is next month."