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Miconazole topical and Discomfort: What Users Say

Brand names: Monistat, Monistat 7, Mitrazol, Monistat 3, Monistat 1 Combination Pack, Azolen, Desenex Antifungal Foot Cream, Micatin, Lotrimin AF Jock Itch Powder Spray, Baza Antifungal, Lotrimin AF Athlete's Foot Powder, Aloe Vesta 2 in 1 Antifungal, Zeasorb-AF, Remedy Antifungal with Olivamine, Secura Antifungal Extra Thick, DermaFungal, Micaderm, Lotrimin AF Athlete's Foot Powder Spray, Monistat-Derm, Miranel AF, Absorbine Antifungal Foot Powder, Critic-Aid Clear AF, Zeasorb-AF Jock Itch, NuZole, Dermagran AF, Soothe & Cool Inzo, Breezee Mist Antifungal, Lotrimin AF Deodorant Powder Spray, Fungoid, Desenex Antifungal Liquid Spray, Aloe Vesta, Micon 7, Desenex Prescription Strength, Fungoid Kit, Ony-Clear, Cruex Prescription Strength, Desenex Jock Itch, M-Zole 3 Micro-Guard Desenex AF Zeasorb-AF Drying Gel Vagistat-3 Desenex Antifungal Atheletes Foot Spray Liquid Tetterine Lotrimin AF Athlete's Foot Spray Triple Paste AF …show all brand names

Discomfort: mentioned by 272 users (6.4%)

Based on user experiences from 4,225 Miconazole topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 71.0%
itching 53.7%
pain 19.1%
discomfort 6.4%
swelling 5.0%
irritation 3.4%
severe pain 1.4%
stinging 1.4%
allergic reaction 1.3%
tingling 1.1%

Reviews for Miconazole topical

Commonly mentioned side effects
  • Ali...
  • Taken for less than 1 month
  • January 28, 2021

For Vaginal Yeast Infection "I’m a Nurse Practitioner, please FDA look into this medication, something is seriously WRONG with this product all of a sudden!! It’s 4:00 AM in the morning and I have not had any sleep because my entire reproductive system feels like someone has put a torch to it. I will not be recommending this to my patients. I’m going to be a mess at work today with no sleep. Praying while I have ice packs on my vagina OUCHHHHHHH!!"

1 / 10
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179 Report
  • Dit...
  • Taken for less than 1 month
  • August 26, 2020

For Vaginal Yeast Infection "0/5 stars. Do not recommend. I used the Monistat 3-Day ovules. I only completed 2 days. I'd rather have the yeast infection. I've never in my life felt uncomfortable like that. I didn't sleep night 1 at all. Night 2 at around 3 am, I took a Benadryl and got a few hours of sleep after sitting in a cold bath, considering sitting on a steel brush for relief. If anyone suggests I ever use Monistat again, I'm calling the cops on them."

1 / 10
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192 Report
  • Boo...
  • Taken for less than 1 month
  • February 20, 2020

For Vaginal Yeast Infection "This is my first yeast infection so of course I was freaking out when I started itching and my vagina started to swell. I called my doctor and was told to get this product and use for 7 days. I didn’t wait till bedtime and chose to use it...BIG MISTAKE! I squatted and injected the cream...couple minutes after it burned but it stopped a little while (about 10-15 minutes later) but it left me sore. However, the following morning I felt better! The swelling was gone and I no longer uncomfortable. I’m now on Day 2 and I injected it laying on my back, knees bent and immediately laid down. This time it slightly burned but overall it was good! I recommend using this. Don’t let the first day scare you! It gets better. It is better to lay flat on your back with your knees bent to inject the cream and immediately lay down so that it won’t come out and cause burning. For the first dosage, try to reduce liquids because urinating after you have applied the cream will be a big discomfort."

10 / 10
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129 Report

Frequently asked questions

  • Ano...
  • February 6, 2020

For Vaginal Yeast Infection "After taking antibiotics for BV, I felt like I was getting a yeast infection, so I got Monistat 7. I used it externally the first day, which burned for a while, then felt better. When I inserted it at bedtime, the burning started again. I have not used Monistat in many years, but I remember it as soothing, not painful. I don't know what they changed about it, but they need to change it back. After about an hour, the burning seems to have let up a little. From reading all the other reviews, at least I know I'm not the only one who is experiencing discomfort. On the upside, I got a little comic relief from some of the reviews. Not that I think everyone's pain is funny, but some of the descriptions are very colorful. Seriously, they need to fix this product because it didn't use to hurt this much. Update: the burning was not as bad the second night. I think after the medication had a couple of days to heal me, the rawness from the infection was better and therefore less burning. The burning on the third night was very minimal."

7 / 10
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91 Report
  • Scr...
  • August 21, 2020

For Vaginal Yeast Infection "I used the Equate generic brand of the Monistat one-dose egg, same exact dosage and ingredients compared to Monistat, along with the external cream that comes with the egg. Two hours after inserting it, an increase in burning and itching happened. It wasn’t unbearable like some of these reviews are saying. I was able to fall asleep still, and when I woke up the next morning, I had no itchiness in my vagina or yeast infection feeling. It’s been a week now, and my infection is gone. If you are sensitive and can’t handle an increase in uncomfortability, then I suggest you see a doctor. If you don’t want to end up with a bill, just use Monistat over-the-counter and be a little bit more uncomfortable for a few hours to kill off your yeast infection. 10 out of 10, I would recommend it to someone to use."

10 / 10
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87 Report

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  • Anonymous
  • March 3, 2020

For Vaginal Yeast Infection "27 weeks pregnant with a yeast infection. My doc recommended that I use Monistat 7. My first day burned like lava!! I almost went to the ER. 2nd day not so bad, but now I'm on my 3rd day and the burning with intense itching is back!! So uncomfortable, I can barely stand it... I honestly don't know how I'm going to get through the whole 7 days..."

4 / 10
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80 Report
  • Kye...
  • Taken for less than 1 month
  • December 19, 2019

For Vaginal Yeast Infection "The only thing getting me through this literal nightmare of a situation is reading these comments and knowing I’m not alone. I took Monistat 1 when I was younger and I’m not sure if my pain tolerance has lowered after childbirth, or if they changed the formula, but FOR THE LOVE OF GOD, DO NOT USE THIS PRODUCT. Unless you want to be up at 2 am holding yourself with a wash rag trying to search ways to get the demon out of you."

1 / 10
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79 Report
  • Mel...
  • Taken for less than 1 month
  • April 4, 2021

For Vaginal Yeast Infection "I am abandoning this treatment on day three because it is extraordinarily uncomfortable to use - it basically feels like a combination of ants biting my cervix and a case of poison ivy in my vagina. It is worse than the yeast infection itself. I suffered through the first couple of days, which were pretty bad, but tonight I just couldn’t take it, and I used my bidet to try to rinse as much of this Monistat hot sauce out of me as possible. It was either that or felt like using a scratcher up in there to try to ease the itch and pain."

1 / 10
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51 Report
  • Can...
  • November 18, 2018

For Vaginal Yeast Infection "The first night of using Monistat 3, I had severe burning and itching right after inserting for about an hour until I fell asleep. I woke up the next morning still feeling the symptoms of my yeast infection. I was hesitant to take it the second night, but I did, and I have to say, it went in comfortably and I had no discomforts the 2nd or 3rd night. If you experience the intense burning and itching, then that means the medicine is working. It may hurt, but it gets the job done. Also, try and keep in mind that typically happy users don’t take their time to go out of their way and review things, saying how great they are; but unhappy users will most definitely find the time to post their review if they hate the product. That’s something I always keep in mind when reading reviews. I wanted to come on and share my experience so people don’t get scared away by all the horrific reviews on here lol."

9 / 10
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76 Report
  • Tro...
  • June 10, 2020

For Vaginal Yeast Infection "I used this product last night, and after about an hour, I was in severe discomfort. The burning was like nothing I experienced before, my skin down there was on fire, really painful. I can’t believe that a medication to treat itching and burning could be so abrasive. I eventually took OTC pain meds (ibuprofen and Tylenol) and a cold compress to get to sleep. Today is better, and the original itching is basically gone. But you really have to go through the fire to get to the relief. Hope the folks at Monistat will work on a gentler formulation that would be just as effective."

1 / 10
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58 Report
  • Fir...
  • Taken for less than 1 month
  • June 2, 2020

For Vaginal Yeast Infection "I’m currently pregnant and my OB recommended I try Monistat to help with my YI. I just tried it less than 30 minutes ago, and OMG the worst pain ever. I can’t handle the burning or itchiness, IDK which one because I am in so much pain and discomfort. This is the first night, IDK how I’m supposed to do it for another 6 nights. I will be calling my OB tomorrow to see if there is an alternative because this stuff is AWFUL!!"

1 / 10
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49 Report
  • AGa...
  • Taken for less than 1 month
  • December 21, 2019

For Vaginal Yeast Infection "Truly would not wish this type of pain on my worst enemy. It’s currently 4 am, and my “cookie” is on fire. I’ve been up for hours, and I can’t go back to sleep because the discomfort is so bad. I used the 3-day Monistat with hopes of it actually healing me, but I most definitely screwed up. I don’t think my yeast infection is gone, and my cookie is probably ruined forever. Not sure how this product is on shelves and also unsure how Google sites actually recommended this flame-throwing product to women. I haven’t had a yeast infection before, so I thought this type of pain was somewhat normal. Turns out Monistat is just utter garbage and wants our cookies to burn to char. If you’re thinking about using Monistat, you may as well just take some poison ivy and a match to your cookie. You’ll feel about the same."

1 / 10
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63 Report
  • Mar...
  • Taken for less than 1 month
  • May 1, 2020

For Vaginal Yeast Infection "I was on (2) antibiotics because of a toothache. The antibiotics caused a yeast infection. The day I noticed the infection was when it was painful to wipe. I went and purchased Monistat 7 because it was a low dosage over a few days, which seemed reasonable because my infection did not seem severe. I used the inserted cream 7 nights straight, refrained from sex, and it cleared by the 6th day. It is uncomfortable at night. I was very fidgety, and the topical cream I only used twice because it felt too hot on me. The first two days after treatment, my vagina still felt wonky (medicine was still leaking), but there was no pain or itch. The 3rd day after the 7-day treatment, everything is back to normal. Though super annoying, it was totally effective and worth it in my experience."

8 / 10
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46 Report
  • Hel...
  • Taken for less than 1 month
  • December 12, 2019

For Vaginal Yeast Infection "So I gave this a 10 because it definitely works, but if I had to rate the overall experience, I would give it a 2. Literally only keeping it above 0 because it is effective. The internal itching you get using this stuff is unbearable! The first night is always the absolute worst, and it gradually gets better every night after. After night 3, there usually isn’t much itching or burning. But my goodness, you would think there was a way to make this work without the discomfort or something they could provide you to ease the discomfort."

10 / 10
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35 Report
  • Jay...
  • Taken for less than 1 month
  • November 16, 2019

For Vaginal Yeast Infection "Stay away!! I used Monistat over a decade ago. Some reviews say that the burning is because it’s not a yeast infection. Untrue! This Monistat is a different formula, and whatever they put in it causes extreme burning! My labia minor and major burned in ways I cannot describe. The inflammation is not minimal! Please don’t purchase this product. On day 1, there was some mild discomfort and itching. Day 2 was by far the worst as the product began to slowly seep out, and I was up all night in pain and agony. Day 3, the “chunks” of the egg start to come out, and I finally felt relief. It is now Day 4, and there is some itching, but barely noticeable. Don’t use this product. Please! The FDA needs to investigate this."

1 / 10
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35 Report
  • Ano...
  • November 21, 2019

For Vaginal Yeast Infection "Day 1 - I inserted Monistat lying down and put it on the vulva and labia, then went to get up to do my nighttime routine (BAD IDEA). The intense burning started immediately and lasted for about an hour. From a scale of 1 to 10, the pain was about an 8. I wanted to get better, so I sucked it up and just went to sleep. Day 2: The next day, I woke up with a swollen vagina. It hurt to pee and walk. I was uncomfortable the entire day and just wanted this to end. I made sure to do my night routine, insert the cream lying down, and go straight to sleep. Surprisingly, there was no burning sensation this night. It was easier. Day 3: It didn’t hurt to pee this time. There’s still minor swelling and redness, but not as bad as Day 2. I think it really is working, so I’m going to continue it. The foul smell is still there, but it’s probably because I still need to finish it. Ladies, I know it burns, and I know it freaking sucks!!! But, get through it, finish it, and get better."

8 / 10
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42 Report
  • Pus...
  • Taken for less than 1 month
  • October 22, 2019

For Vaginal Yeast Infection "It works. The worse that your YI is, the worse it will hurt. As the inside of your vaginal area heals, the less discomfort you experience. I am pregnant with my first child, and this is my first YI. I have tried all-natural ACV and coconut oil, and tea tree and baking soda, prescriptions, and AZO. All slowed the YI symptoms but did not kill the candida. I'm on day 6 on the Monistat 7. There wasn't much discomfort like the first 3 days. And the symptoms of my YI are basically gone. They recommend pregnant women finish the whole treatment to fully kill the infections. It does work. Wish I would have tried it first. But I'm an all-natural girl, I had to try all the safe ways first."

6 / 10
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28 Report
  • THI...
  • Taken for less than 1 month
  • November 27, 2019

For Vaginal Yeast Infection "Oh my word... as many of you have already said: I had to take amoxicillin for an infection, and it wiped out my good bacteria in my vagina, leading to a HORRID yeast infection (YI). I’d taken the Monistat eggs before with no issue... went up to Walmart today to get it, and they only had the Monistat 3 cream. PLEASE do yourself a favor and avoid this med! My vagina is 1,000,000,000 times more uncomfortable now than I was before inserting the cream! It is truly something awful! Fire ants, wearing scratchy wool sweaters, set on fire, crawling up my vag! I am considering going to the ER! Nothing is helping! Never using this stuff again! (-)5⭐️⭐️⭐️⭐️⭐️"

1 / 10
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25 Report
  • Ben...
  • January 19, 2020

For Vaginal Yeast Infection "Listen!!! It’s 11:56 pm and I just went in the tub to wash out the Monistat 3 medicine! Day 1 was painful but bearable pain. Felt extreme itching and burning inside my vagina, and the discomfort was better without the treatment. Day two was similar, but I felt the infection going away by then. Day three, I felt I didn’t need the treatment, but I wanted to finish it off... Now I’m on here typing, giving my review!!! And I’m here laying in pain because it’s causing itching in my vagina that I never had!!! It feels like imbedded worms or fleshy parasites."

2 / 10
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31 Report
  • GOD...
  • January 8, 2020

For Vaginal Yeast Infection "Ok, so I've had my YI for about 5 days now, and I've finally bought Monistat 7. Oh my! After I inserted my first application, I felt instant discomfort. I was so scared because it was burning and itching, and you really can't do anything to stop it. It's been about 30 mins, and I have been putting cold pieces of tissue on my lady parts, and it had been helping. Hopefully, tomorrow is easy. Wish me luck, ladies!"

4 / 10
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20 Report
  • Sar...
  • September 16, 2019

For Vaginal Yeast Infection "I used Monistat 7 two months ago, and I felt the itchy sensation everyone is talking about. I felt it the first three nights, and on the fourth night, no itchiness at all. I think the itchiness is because the cream is killing the fungal infection. I'm using the cream again just to make sure it has all gone for good. The last doses, there is no itchiness or any discomfort. I highly recommend it."

9 / 10
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21 Report
  • YIa...
  • October 28, 2018

For Vaginal Yeast Infection "The last time I had a YI, it was BAD. I had my mom get me the Monistat day 3. Within minutes of using it, I was in the bathroom, in excruciating pain trying to get whatever I put in me out. I'm not lying when I say it was possibly the most painful thing I’ve endured. I ended up going with the day 7 another time, and it was a little less intense. I do think the severity of the pain depends on how bad your infection is. I currently have a YI, and I’m using the day 3 again. I’ve had it in for about 15-20 minutes, and I’ve only had a little bit of discomfort, but VERY doable. The medicine is killing off the bad yeast, so obviously it’s probably not meant to feel like sunshine and rainbows. I will say vagisil anti-itch cream helped me a lot. Hopefully, this comment has given someone comfort, as I have been in this situation before and have struggled through the pain of Monistat. Hang in there, it’s worth the infection being done in the end."

3 / 10
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21 Report
  • Lin...
  • March 20, 2019

For Vaginal Yeast Infection "It ain't that bad, y'all. Yes, it itches. Yes, it's uncomfortable. It's worth getting rid of Candida. I'd use the stuff daily if it meant never getting another yeast infection. Pro Monistat tip: before inserting Monistat, spread Aloe Vera gel and Tea Tree oil onto a few maxi pads and put them in the fridge. When the discomfort hits, slap one of those suckers on for instant relief. Don't freeze them or you're gonna freezer burn the bajeezus out of your hoo-hah."

8 / 10
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26 Report
  • App...
  • Taken for less than 1 month
  • June 7, 2020

For Vaginal Yeast Infection "I was a bit skeptical about trying this one because of all the reviews saying it caused burning and itching worse than the infection itself. But I had the worst burning and itching sensation ever and didn’t have access to a doctor right away, so I had no choice. I was up all night because I was in so much pain. Then finally at 7 am, I went to Walmart to buy this product. I inserted the little egg at 7:43 am. And I put the cream everywhere on the outside. I instantly felt relief and was able to go to sleep. It’s now 5:16 pm, and I’m still feeling okay. Still a little discomfort, but a lot better than what I was feeling before. I read from the reviews it takes a couple of days for it to fully disappear, so hoping these next few days fly by."

9 / 10
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20 Report
  • Can...
  • Taken for less than 1 month
  • April 30, 2020

For Vaginal Yeast Infection "OMG! So before I used this Monistat cream, I inserted plain, natural, low-fat yogurt into my vagina once a day. I didn’t like the mess it made and how often it would leak out of my vagina. I decided to purchase the Monistat cream this morning at around 9. I took a shower, and then I inserted the Monistat cream. I’m thinking to myself, “Ok, maybe I won’t burn this time.” Literally, 10 seconds later, the most intense burning sensation eeevvverrrrrrr. The itching is so intense as well. I tried to lay down to take a nap, it’s just so uncomfortable. I literally sit with my legs crossed."

3 / 10
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19 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.