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Miconazole use while Breastfeeding

Medically reviewed by Last updated on Dec 17, 2021.

Drugs containing Miconazole: Monistat, Monistat 1 Combination Pack, Monistat 3, Monistat 7, Mitrazol, Zeasorb-AF, Aloe Vesta, Vagistat-3, Oravig, Micatin, Show all 59 »Fungoid, Desenex Jock Itch, Zeasorb-AF Lotion/Powder, Baza Antifungal, Desenex Antifungal Atheletes Foot Spray Liquid, Lotrimin AF Athlete's Foot Powder, Azolen, NuZole, Dermagran AF, Micon 7, Yeast-X Int, Desenex Prescription Strength, Lotrimin AF Athlete's Foot Powder Spray, Monistat-Derm, Miranel AF, Lotrimin AF Jock Itch Powder Spray, Absorbine Antifungal Foot Powder, Critic-Aid Clear AF, Zeasorb-AF Jock Itch, Remedy Antifungal with Olivamine, Soothe & Cool Inzo, Breezee Mist Antifungal, Lotrimin AF Deodorant Powder Spray, Desenex Antifungal Liquid Spray, Micatin Liquid Foot, Micatin Foot Powder, Micatin Foot Powder Deodorant, Fungoid Kit, Ony-Clear, M-Zole Dual Pack, Cruex Prescription Strength, Micatin Cooling Action, Micatin Jock Itch, Aloe Vesta 2 in 1 Antifungal, Desenex Antifungal Foot Cream, M-Zole 3, Micro-Guard, Desenex AF, Secura Antifungal, Secura Antifungal Extra Thick, DermaFungal, Zeasorb-AF Drying Gel, Tetterine, Lotrimin AF Athlete's Foot Spray, Triple Paste AF, Micaderm, Daktozin, Vusion, Rash Relief Antifungal

Miconazole Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because miconazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. However, miconazole ointment appears to have no advantage over lanolin for treating sore nipples during breastfeeding[1] and a survey of members of the Academy of Breastfeeding Medicine found topical miconazole is rarely prescribed to nursing mothers to treat thrush.[2] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

In a randomized, double-bind trial, lanolin was compared to an all-purpose nipple ointment containing mupirocin 1%, betamethasone 0.05%, and miconazole 2% for painful nipples while nursing in the first 2 weeks postpartum. The two treatments were equally effective in reducing nipple pain, nipple healing time, breastfeeding duration, breastfeeding exclusivity rate, mastitis and nipple symptoms, side effects or maternal satisfaction with treatment.[1]

Alternate Drugs to Consider

Clotrimazole, Fluconazole, Nystatin


Dennis CL, Schottle N, Hodnett E, McQueen K. An all-purpose nipple ointment versus lanolin in treating painful damaged nipples in breastfeeding women: A randomized controlled trial. Breastfeed Med. 2012;7:473-9. [PubMed: 22428572]
Brent NB. Thrush in the breastfeeding dyad: results of a survey on diagnosis and treatment. Clin Pediatr (Phila). 2001;40:503-6. [PubMed: 11583049]
Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. [PubMed: 14623482]

Substance Identification

Substance Name


CAS Registry Number


Drug Class

  • Breast Feeding
  • Lactation
  • Antifungal Agents
  • Dermatologic Agents

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Further information

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