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Miconazole use while Breastfeeding

Drugs containing Miconazole: Mitrazol, Monistat, Monistat 7, Zeasorb-AF, Aloe Vesta, Baza Antifungal, Micatin, Desenex Prescription Strength, Vusion, Monistat 3-Day Combination Pack, Show all 62 »Monistat 3-Day Ovule Combination Pack, Secura Antifungal, Zeasorb-AF Lotion/Powder, Fungoid, Monistat 1-Day Ovule Combination Pack, Tetterine, Rash Relief Antifungal, Cruex Prescription Strength, Lotrimin AF Athlete's Foot Spray, Lotrimin AF Jock Itch Powder Spray, Micon 7, Dermagran AF, Micro-Guard, Desenex AF, Secura Antifungal Extra Thick, M-Zole 3, Desenex Jock Itch, Micatin Jock Itch, Aloe Vesta 2 in 1 Antifungal, DermaFungal, Desenex Antifungal Foot Cream, Desenex Antifungal Atheletes Foot Spray Liquid, Micaderm, Daktozin, Micatin Cooling Action, Monistat 1-Day or Night Combination Pack, Triple Paste AF, Vagistat-3, Monistat-1 Dual Pack, Lotrimin AF Athlete's Foot Powder, Zeasorb-AF Drying Gel, Soothe & Cool Inzo, Zeasorb-AF Jock Itch, NuZole, Monistat 7-Day Combination Pack, Remedy Antifungal with Olivamine, Critic-Aid Clear AF, Absorbine Antifungal Foot Powder, Monistat-Derm, Miranel AF, Azolen, Oravig, Breezee Mist Antifungal, Micatin Foot Powder Deodorant, Fungoid Kit, Ony-Clear, Micatin Foot Powder, Micatin Liquid Foot, Lotrimin AF Deodorant Powder Spray, Desenex Antifungal Liquid Spray, Yeast-X Int, M-Zole Dual Pack

Miconazole Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because miconazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. However, miconazole ointment appears to have no advantage over lanolin for treating sore nipples during breastfeeding[1] and a survey of members of the Academy of Breastfeeding Medicine found topical miconazole is rarely prescribed to nursing mothers to treat thrush.[2] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

In a randomized, double-bind trial, lanolin was compared to an all-purpose nipple ointment containing mupirocin 1%, betamethasone 0.05%, and miconazole 2% for painful nipples while nursing in the first 2 weeks postpartum. The two treatments were equally effective in reducing nipple pain, nipple healing time, breastfeeding duration, breastfeeding exclusivity rate, mastitis and nipple symptoms, side effects or maternal satisfaction with treatment.[1]

Alternate Drugs to Consider

Clotrimazole, Fluconazole, Nystatin

References

1. Dennis CL, Schottle N, Hodnett E, McQueen K. An all-purpose nipple ointment versus lanolin in treating painful damaged nipples in breastfeeding women: A randomized controlled trial. Breastfeed Med. 2012;7:473-9. PMID: 22428572

2. Brent NB. Thrush in the breastfeeding dyad: results of a survey on diagnosis and treatment. Clin Pediatr (Phila). 2001;40:503-6. PMID: 11583049

3. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Miconazole Identification

Substance Name

Miconazole

CAS Registry Number

22916-47-8

Drug Class

Antifungal Agents

Dermatologic Agents

Administrative Information

LactMed Record Number

368

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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