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Miconazole use while Breastfeeding

Drugs containing Miconazole: Monistat, Monistat 7, Monistat 1-Day or Night Combination Pack, Monistat 3-Day Combination Pack, Mitrazol, Vusion, Micatin, Zeasorb-AF, Baza Antifungal, Aloe Vesta, Show all 64 »Cruex Prescription Strength, Secura Antifungal, Vagistat-3, Daktozin, Oravig, Desenex Antifungal Foot Cream, Tetterine, Triple Paste AF, Aloe Vesta 2 in 1 Antifungal, Miranel AF, Monistat 1-Day Ovule Combination Pack, Lotrimin AF Jock Itch Powder Spray, Lotrimin AF Deodorant Powder Spray, Micatin Cooling Action, Micatin Jock Itch, Desenex Jock Itch, Zeasorb-AF Lotion/Powder, M-Zole 3, Micro-Guard, Desenex AF, Zeasorb-AF Drying Gel, Secura Antifungal Extra Thick, DermaFungal, Desenex Antifungal Atheletes Foot Spray Liquid, Monistat-1 Dual Pack, Lotrimin AF Athlete's Foot Powder, Lotrimin AF Athlete's Foot Spray, Micaderm, Monistat 3-Day Ovule Combination Pack, Ony-Clear, M-Zole Dual Pack, Soothe & Cool Inzo, Fungoid Kit, Dermagran AF, Lotrimin AF Athlete's Foot Powder Spray, Monistat-Derm, Azolen, Monistat 1 Day Complete Therapy, Absorbine Antifungal Foot Powder, Critic-Aid Clear AF, Zeasorb-AF Jock Itch, NuZole, Monistat 7-Day Combination Pack, Micatin Foot Powder Deodorant, Remedy Antifungal with Olivamine, Breezee Mist Antifungal, Fungoid, Desenex Antifungal Liquid Spray, Micon 7, Yeast-X Int, Micatin Liquid Foot, Micatin Foot Powder, Desenex Prescription Strength, Rash Relief Antifungal

Medically reviewed on Sep 7, 2018

Miconazole Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because miconazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. However, miconazole ointment appears to have no advantage over lanolin for treating sore nipples during breastfeeding[1] and a survey of members of the Academy of Breastfeeding Medicine found topical miconazole is rarely prescribed to nursing mothers to treat thrush.[2] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

In a randomized, double-bind trial, lanolin was compared to an all-purpose nipple ointment containing mupirocin 1%, betamethasone 0.05%, and miconazole 2% for painful nipples while nursing in the first 2 weeks postpartum. The two treatments were equally effective in reducing nipple pain, nipple healing time, breastfeeding duration, breastfeeding exclusivity rate, mastitis and nipple symptoms, side effects or maternal satisfaction with treatment.[1]

Alternate Drugs to Consider

Clotrimazole, Fluconazole, Nystatin

References

1. Dennis CL, Schottle N, Hodnett E, McQueen K. An all-purpose nipple ointment versus lanolin in treating painful damaged nipples in breastfeeding women: A randomized controlled trial. Breastfeed Med. 2012;7:473-9. PMID: 22428572

2. Brent NB. Thrush in the breastfeeding dyad: results of a survey on diagnosis and treatment. Clin Pediatr (Phila). 2001;40:503-6. PMID: 11583049

3. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Miconazole Identification

Substance Name

Miconazole

CAS Registry Number

22916-47-8

Drug Class

Antifungal Agents

Dermatologic Agents

Administrative Information

LactMed Record Number

368

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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