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Miconazole topical Pregnancy and Breastfeeding Warnings

Miconazole topical is also known as: Absorbine Antifungal Foot Powder, Aloe Vesta, Aloe Vesta 2 in 1 Antifungal, Azolen, Baza Antifungal, Cruex Prescription Strength, Desenex Antifungal Foot Cream, Lotrimin AF Athlete's Foot Powder Spray, Lotrimin AF Deodorant Powder Spray, Lotrimin AF Jock Itch Powder Spray, Micatin, Miranel AF, Mitrazol, Monistat, Monistat 1 Day Complete Therapy, Monistat 1-Day Ovule Combination Pack, Monistat 1-Day or Night Combination Pack, Monistat 3-Day Combination Pack, Monistat 7, Monistat-Derm, Secura Antifungal, Tetterine, Triple Paste AF, Vagistat-3, Zeasorb-AF

Medically reviewed on Sep 13, 2018

Miconazole topical Pregnancy Warnings

Pregnancy predisposes patients to the development of vaginal candidiasis due to changes in the vaginal tract. Miconazole has been used in several clinical trials for the treatment of vaginal candidiasis, generally during the second and third trimester, without evidence of fetal harm.

In a review of 229,101 deliveries to Michigan Medicaid patients, 7266 first-trimester exposures to miconazole and 31,503 exposures any time during pregnancy were recorded. A total of 304 birth defects were reported with first trimester exposure (273 expected) and included (observed/expected) 77/73 cardiovascular defects, 14/13 clefts, 3 spina bifida, 4/4 oral clefts, 22/15 polydactyly, 12/9 limb reductions, and 20/17 hypospadias (written communication, Franz Rosa, MD, Food and Drug Administration, 1994). These data do not support an association between first-trimester miconazole use and birth defects.

Miconazole has not officially been assigned to a pregnancy category by the FDA. In clinical trials, miconazole treatment of vaginal candidiasis has not been associated with fetal harm. Miconazole is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

See references

Miconazole topical Breastfeeding Warnings

There are no data on the excretion of miconazole into human milk.

See references

References for pregnancy information

  1. "Product Information. Monistat (miconazole)." Ortho Pharmaceutical Corporation, Raritan, NJ.
  2. Weisberg M "Treatment of vaginal candidiasis in pregnant women." Clin Ther 8 (1986): 563-7

References for breastfeeding information

  1. "Product Information. Monistat (miconazole)." Ortho Pharmaceutical Corporation, Raritan, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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