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Taltz User Reviews & Ratings (Page 5)

Taltz has an average rating of 7.2 out of 10 from a total of 225 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Taltz

Commonly mentioned side effects
  • Sle...
  • Taken for 1 to 6 months
  • December 5, 2019

For Plaque Psoriasis "Clear after 2 months. Feel fatigued most of the time. Hope it passes with time. Have been on many biologics. Noticed my teeth hurt and several seem loose or have mobility issues. Same thing happened when I was on Humira. Neither the doctor nor dentist have answers, but the mobility is a concern. Any others have this issue?"

8 / 10
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  • Rud...
  • September 2, 2017

For Plaque Psoriasis "Started Taltz on 4/29/17 and took my final dose a few weeks ago. I had such high hopes, but it did not work for me. I'd taken Humira for years with amazing results until it stopped working last October. Then I tried Stelara. Skin got worse, much worse. Taltz seemed to help a little at first, thinned out some of the plaques. Then it stopped doing even that, and my skin has gotten progressively worse. Another note on Taltz: the injections hurt. I found them by far more painful than any others. And it didn't stop hurting after the injection. Also, I had huge injection site reactions from it, 6-inch welts. It would have been worth the pain if it had worked. It didn't."

2 / 10
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  • Mor...
  • September 18, 2018

For Plaque Psoriasis "Have lived with severe plaque psoriasis for about 23 years. Never took any biologics to treat it. Within 3 days, I developed hives and severely itchy eyes, but that was controlled quickly and easily with antihistamine. Within a week, 90% of plaques were GONE. By Day 10, only the thickest plaques left any buildup, although those areas did appear to start to get rougher. Week 2 injection seems to maintain it, though midway through Week 3 some itching has redeveloped, though it may only be a very mild reaction. Insurance won't cover since I didn't try Humira, but Taltz has been probably 90% effective so far and I doubt that Humira or Enbrel would have come even close to alleviating any symptoms given my experience so far. Injection site pain is moderate, but I could see how it might be difficult for less hardened people. So far, no major illness, but I rarely get sick and it has only been a month. Time will tell."

8 / 10
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Frequently asked questions

  • I...
  • Taken for 1 to 6 months
  • July 14, 2017

For Plaque Psoriasis "I took Stelara for plaque psoriasis for about four years, and it worked very well-until I had to miss a dose because I was having knee surgery. After 3 1/2 months, I resumed taking Stelara, but my body no longer responded to it, and I started getting a lot of activity on my legs. My doctor suggested switching to TALTZ, but I was put off by the initial starter doses and the monthly maintenance dose. (After all, Stelara is only one shot every 3 months.) Nevertheless, I decided to read online comments about TALTZ and was encouraged, but skeptical about some people saying they saw improvement in days. Well, now I'm one of those people. I saw improvement in just 4 days, I'm on week 6 of treatment."

10 / 10
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  • Pso...
  • Taken for 1 to 6 months
  • July 22, 2017

For Plaque Psoriasis "Another review after 12 weeks, no change in my condition. Taltz is not helping and having the same symptoms as described by another reviewer. Fine rash on chest, face, and genital itching. My psoriasis lesions are starting to get worse on my hands, elbows, and ankles. I had been on Otezla, which worked for about 18 months, then I developed severe psoriasis on my hands that I cannot get rid of. Humira made everything worse, and I developed thick plaques on my hands and feet. Taltz helped the plaques on the palms of my hands and the bottoms of my feet, but cannot clear the top of my hands, which are my most visible areas and very embarrassing. I take Estilar, clobetasol, and triamcinolone topically. Nothing is working. Biologics have made my psoriasis worse than ever."

2 / 10
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  • Sei...
  • Taken for 1 to 2 years
  • August 27, 2017

For Plaque Psoriasis "I have had plaque psoriasis for 25 years and have started Taltz 1 year ago. It completely cleared my skin. I used Stelara for 5 years prior to Taltz, but still had some psoriasis left on my elbows and some spots on my lower body. I am able to wear the clothes I want at work in summer and wear swimsuits in the summer! My life is changed. I wear dresses with short sleeves with no tights! I don't have to wear cardigans/long pants in the summer! I thank Lilly company for producing the drug and thank the co-payment assisting program! Thank you so much!!"

10 / 10
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  • Bra...
  • Taken for 1 to 6 months
  • November 8, 2023

For Psoriatic Arthritis "I'm a 60-year-old male, in good condition with no health issues other than mild-moderate PsA for 20+ years. My first dose of Taltz was in Nov. 2022. I came down with terrible food poisoning about 10 days thereafter and never went back on the drug. Though medically unsubstantiated, I believe there was a correlation. Took another chance with the first dose in Sep '23 and the second 4 weeks later. Up until my second dose, no side effects at all. Then I came down with a sore throat, cough, and hoarseness, which persisted for about two weeks then went away. However, my bowel habits drastically changed in terms of increased frequency, urgency, and quality with loose/diarrhea stools. As of Nov 8, things have gotten a little better alternating between the former and normal consistency stools, but I am NOT back to normal. Although I found Taltz to help in this short time, I'm off the drug and won't go back on an IL-17 inhibitor given its potential impact on the gut microbiome and risks with IBS/IBD."

3 / 10
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More FAQ

  • Hne...
  • Taken for 1 to 6 months
  • July 30, 2017

For Plaque Psoriasis "This is the only drug that has completely cured my psoriasis. I have taken Sterla, Humira, and Embrel, pretty much all injections. Sterla kept it under control, and Taltz cured it. I have found confidence, I can wear a short bathing suit, anything I want now, and not have people look at me like I'm contagious."

10 / 10
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  • tal...
  • Taken for 1 to 6 months
  • January 16, 2018

For Plaque Psoriasis "Update on my Taltz. Been on it for almost 6 months now and am 100% clear. I saw clearing 3 weeks into taking the prescription and at 6 weeks, 100% clear, which has been sustained through this time. Amazing experience for me and no side effects thus far. Thank you, Taltz, for making a difference in my life!"

10 / 10
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  • Mar...
  • October 24, 2016

For Plaque Psoriasis "My experience with Taltz has been wonderful as far as the improvement, but the cost of $12,500 is really outrageous. I was started by my dermatologist on samples and then hit with the price. I feel that this is discrimination and price gouging. If I were in a lower income bracket, I would only have to pay $25.00, so apparently the cost to me and others is supplementing other people. I get regular phone calls from a nice little girl from Lilly Cares, and I told her it's more like Lilly doesn't give a damn. I am now consulting an attorney and looking for other medications."

10 / 10
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  • Hyj...
  • Taken for 1 to 2 years
  • November 10, 2020

For Psoriasis "I was switched to Taltz after 10 years on Humira for severe plaque psoriasis. I had side effects from the start: severe exhaustion, mouth ulcers, red burning eyes, exaggerated response at the injection site, felt like I had the flu for two days after injection, hair loss, extreme folliculitis, etc. In addition, Taltz didn’t even start to combat the psoriasis that affects my toenails, which has gotten so painful I had to buy a half size larger in trainers. I gave it a year and a half, as I was part of a study, but thankfully, I’m going back to Humira! The exhaustion was the worst part; it’s really affected me."

6 / 10
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  • Dis...
  • Taken for 6 months to 1 year
  • April 16, 2018

For Plaque Psoriasis "Worse decision of my life to start biologics. I had a mild to moderate case treated with topicals. Decided to pursue a biologic in search of a drug to finally give me clear skin. On the contrary, this has worsened my psoriasis, I now have the worst case in 25 years. Biologics have actually triggered psoriasis in areas I never had before. It is resistant to biologics and now even resistant to topicals. I have tried Otezla, Humira, Taltz, going to try Tremfya next. No help in sight. Not sure what to do next."

1 / 10
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  • Con...
  • Taken for 6 months to 1 year
  • June 9, 2022

For Psoriasis "My 30-year-old son was started on Taltz for a moderate case of psoriasis and was on it for around 7 months when, out of the blue, he developed a very severe case of ulcerative colitis. It was classified as pan-colitis involving his entire colon. The GI doctor who did his colonoscopy said it was the worst case he had ever seen and listed it as such on the scale they use to determine severity. My son had NEVER had any kind of issue with his bowel before. He ended up hospitalized in extreme pain for over two weeks, and at one point, we were concerned they were going to have to remove his entire colon because they couldn't stop the pain or bleeding with steroids. He couldn't eat and was put on TPN for nutrition. He ended up losing 40 pounds. He eventually responded to a medication called Remicade and was able to leave the hospital. He has been informed by his doctors that he will have ulcerative colitis for the rest of his life and all the pain, discomfort, and expense that will entail."

1 / 10
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  • Lou...
  • Taken for 1 to 6 months
  • January 25, 2020

For Plaque Psoriasis "I've been on a few psoriasis medications and happy to say Taltz has worked the best for me. The injection does sting more than another, I haven't found my 'sweet spot' yet. I don't mind, the results are terrific."

10 / 10
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  • CAS...
  • Taken for less than 1 month
  • July 8, 2018

For Plaque Psoriasis "I was 90% covered. I took my first double dose, and 5 days later, I was 60% clearer. I put on shorts today for the first time in a long time. All I can say is that at this rate, I will soon be 100% clear. I hope it keeps working."

8 / 10
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  • Pso...
  • Taken for 1 to 6 months
  • August 12, 2017

For Plaque Psoriasis "4 months on Taltz, now on maintenance dosage, and psoriasis plaques getting worse. I am disappointed with results, this is 3rd drug failure. Failed Otezla, Humira, now Taltz. Systematic drugs have worsened my psoriasis. I should have stuck to topicals. I feel there is no going back now, they have caused worsening of my symptoms. I had previously controlled my symptoms with topicals, and now they don't work either."

2 / 10
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  • Ter...
  • June 30, 2017

For Plaque Psoriasis "Took for 3 months just before the first monthly injection, got itchy in the genital area. Thought it was a yeast infection. Then eyelids swelled, and I broke out in different rashes all over the body. My chest broke out in what looked like a heat rash that went up my neck and half my face. My stomach has red dots all over, and the folds in my skin are raised and itchy. This has been since before Memorial. Been on prednisone now for the second time. Any idea when these reactions will go away? Stopped taking before the first monthly injection."

3 / 10
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  • Jes...
  • August 31, 2017

For Plaque Psoriasis "I have been on Taltz for about 4 months. I saw results right away. It has even helped my rheumatoid arthritis some. The only side effect I have is mild cold symptoms, which go away pretty fast. The biggest drawback of this medicine is it lowers my immune system, which sucks because I get sick a lot more now than without it. I got the flu recently, it lasted 7 days, and it was pretty severe. I have tried lots of other biologics, you name it, I have tried it. Before Taltz, I was on Cosentyx, it was great except it gave me very bad mouth sores. With Taltz, I only had to pay a $5.00 co-pay, my insurance and Lilly took care of the rest. I am pretty much 99.9% clear taking this medication."

9 / 10
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  • Dav...
  • Taken for 1 to 6 months
  • October 18, 2023

For Psoriatic Arthritis "Ok, so I'm only 45 days in after 18 months on Otezla, and I could not be more excited about Taltz. For the past 18 months, I experienced nausea twice a day after taking Otezla. I tried everything - with foods, without, etc., and nothing seemed to work. That drug did happen to give me relief - 7/10 from the arthritis, though skin conditions didn't change much, but they weren't 'that bad.' 45 days in on Taltz and I feel like a million bucks. The arthritis relief is 9/10, the skin condition has improved, and I have zero nausea and only have to do one simple injection a month."

10 / 10
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  • Wif...
  • Taken for 1 to 6 months
  • March 19, 2018

For Plaque Psoriasis "My husband had severe plaque psoriasis for over 20 years. Nothing has come close to clearing it until Taltz. One week after the initial dose, we could see a significant difference. He is plaque-free now! Looking forward to our first vacation that he will wear shorts and swim trunks in a few weeks!! He has had a very intense sinus infection, but cleared with antibiotics, but still had some recurring drainage. But...a few weeks ago, he injected it in his thigh instead of the stomach. Shortly after, he began having knee pain in that leg. It has increased to the point that it is difficult to walk. Has anyone else experienced this?"

8 / 10
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  • Bre...
  • Taken for 1 to 6 months
  • February 25, 2021

For Psoriasis "I've been on Taltz now for almost a month. I started with 2 auto-injections at once and then now doing 80 mg every 2 weeks. I have plaque and guttate psoriasis, which my dermatologist has classified as erythrodermic psoriasis. My entire body is covered, and this has never happened to me before. I’m 27 years old, and I've had this flare-up for 8 months. Now I’m experiencing something new, though, since starting the Taltz. I've done 3 injections so far. My flare-up hasn’t gotten better at all, like whatsoever. Not even a little bit. In fact, my patches are getting larger than they ever have been. I have no side effects so far from taking Taltz, but is it normal for my flare-up flakes to combine and get larger? I’m not experiencing new flakes, but the ones I have are starting to connect together and form larger portions. I’m literally covered from chest down, also in my scalp and back of my neck. I’m starting to feel defeated, and I just hope that this doesn’t mean it’s not working :)"

5 / 10
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  • Lin...
  • Taken for less than 1 month
  • October 12, 2020

For Plaque Psoriasis "I feel so disappointed about the outcome of TALTZ. The first few days were fine, I didn’t have joint pain. Then things changed, I had side effects of headache, feeling as if I was getting sick, hot, sweating. The next wave of side effects was dizziness and weakness all over. It was hard to stay out of bed, and I slept for three days! I had burning eyes, too. I feel defeated, as I have been on three meds with no success."

2 / 10
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  • Cle...
  • Taken for less than 1 month
  • June 15, 2017

For Plaque Psoriasis "I tried this drug but had terrible injection site reactions to it. My doctor switched me to Cosentyx, and I could not be happier. They have a plan that brings my copay down to $0, and it's not based on income. My skin is basically clear just in time for swimsuit season!!"

10 / 10
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  • Pat...
  • Taken for 1 to 2 years
  • October 2, 2023

For Ankylosing Spondylitis "I was very hesitant to begin with Taltz. I thought I would not be able to inject myself and was concerned about the side effects. However, the injection is so easy and painless. I have been on Taltz for about 15 months and I have experienced no side effects. With my condition, I experience high inflammation, a lot of stiffness and have a hard time climbing steps. I could not walk with any speed. Since starting Taltz, I have no aches and pains. I can climb up steps without holding onto the rail, my stiffness is minimal, my inflammation levels are low, I can even touch my toes, and I am able to walk at a quicker pace. This medication has saved me! I have insurance through my job which covered the medication 100%. I am retiring and will be unable to continue with Taltz as it is not covered by Medicare or prescription drug coverage, and the cost is beyond anything I could afford."

10 / 10
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  • Mid...
  • February 18, 2021

For Psoriasis "Guttate psoriasis over 50% of legs for 20 years. I’ve tried light therapy, steroid creams, Tazorac, Otezla, and Cosentyx. Otezla made me nauseous and did nothing. Creams would help slightly, but it took weeks and also left my skin raw and peeling. Cosentyx for 9 months made them slightly smaller, but no real noticeable change. Just had my week 2 dose of Taltz. I have to say it might be just the initial loading dose of a biologic repeating, but it is actually better. A long way to go, but I am hopeful. And I agree that the autoinjector pen is ridiculously painful. Brings tears, and I am pretty tough. It is short-lived though, and praying this biologic finally makes it to where I can wear shorts."

7 / 10
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