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Medications for Melanoma, Metastatic

Metastatic melanoma is where the cancerous skin tumor has spread to parts of the body remote from the site of the primary tumor.

Drugs used to treat Melanoma, Metastatic

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Mekinist 9.0 1 review
Rx D N

Generic name: trametinib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

trametinib 9.0 1 review
Rx D N

Generic name: trametinib systemic

Brand name:  Mekinist

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

nivolumab 8.0 5 reviews
Rx N

Generic name: nivolumab systemic

Brand name:  Opdivo

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Opdivo 8.0 4 reviews
Rx N

Generic name: nivolumab systemic

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

dabrafenib 7.5 2 reviews
Rx D N

Generic name: dabrafenib systemic

Brand name:  Tafinlar

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Tafinlar 7.5 2 reviews
Rx D N

Generic name: dabrafenib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

pembrolizumab 6.7 15 reviews
Rx D N

Generic name: pembrolizumab systemic

Brand name:  Keytruda

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Keytruda 6.5 14 reviews
Rx D N

Generic name: pembrolizumab systemic

Drug class: anti-PD-1 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

vemurafenib 6.3 4 reviews
Rx D N

Generic name: vemurafenib systemic

Brand name:  Zelboraf

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Zelboraf 6.3 4 reviews
Rx D N

Generic name: vemurafenib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

temozolomide Off-label 5.0 2 reviews
Rx D N

Generic name: temozolomide systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

aldesleukin Rate Add review
Rx C N

Generic name: aldesleukin systemic

Brand name:  Proleukin

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

binimetinib Rate Add review
Rx N

Generic name: binimetinib systemic

Brand name:  Mektovi

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Braftovi Rate Add review
Rx N

Generic name: encorafenib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

cobimetinib Rate Add review
Rx N

Generic name: cobimetinib systemic

Brand name:  Cotellic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Cotellic Rate Add review
Rx N

Generic name: cobimetinib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

dacarbazine Rate Add review
Rx C N

Generic name: dacarbazine systemic

Drug class: alkylating agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

encorafenib Rate Add review
Rx N

Generic name: encorafenib systemic

Brand name:  Braftovi

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Imlygic Rate Add review
Rx N

Generic name: talimogene laherparepvec systemic

Drug class: miscellaneous antineoplastics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ipilimumab Rate Add review
Rx C N

Generic name: ipilimumab systemic

Brand name:  Yervoy

Drug class: anti-CTLA-4 monoclonal antibodies

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

isotretinoin Off-label Rate Add review
Rx X N X

Generic name: isotretinoin systemic

Drug class: miscellaneous antineoplastics, miscellaneous uncategorized agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Mektovi Rate Add review
Rx N

Generic name: binimetinib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

peginterferon alfa-2b Rate Add review
Rx C N

Generic name: peginterferon alfa-2b systemic

Brand names:  PegIntron, Sylatron

Drug class: antineoplastic interferons, antiviral interferons

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

PegIntron Rate Add review
Rx C N

Generic name: peginterferon alfa-2b systemic

Drug class: antineoplastic interferons, antiviral interferons

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Proleukin Rate Add review
Rx C N

Generic name: aldesleukin systemic

Drug class: miscellaneous antineoplastics, interleukins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Learn more about Melanoma, Metastatic

IBM Watson Micromedex

Drugs.com Health Center

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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