Trametinib for Melanoma, Metastatic User Reviews

• kee...
• April 21, 2014

"Have been on Mekinist and Dabrafenib for 2 weeks only. So far, melanomas have reduced in size. Blood test results were good. Hoping it continues, but I must stress it is only early days for me. Two combined drugs are working as they should. Some nausea, aching, and itchiness. But taking antihistamines. Melanomas are in the spine, so pain is expected."

• amb...
• Taken for 6 months to 1 year
• July 17, 2023

"Stage 3 metastatic melanoma, tried Keytruda, did not work, tried Zelboraf and Cotellic, made me sick, sick, changed doctor. I am on Tafinlar and Mekinist for 7 months now. No cancer recurrence. Mild side effects include moderate dizziness, intermittent diarrhea, weight loss, intermittent nausea. Muscle fatigue and soreness. Occasional headache. No fevers. All tolerable! Clean scans!!! Most importantly, Taf 2 tablets 2 times a day, Mek 3 tablets 1 time a day. The biggest challenge is taking them on an empty stomach. I am also a type 2 diabetic. My sugars have risen quite a bit and I have had to double my metformin. That's not fun."