Trametinib User Reviews & Ratings

• kee...
• April 21, 2014

For Melanoma, Metastatic "Have been on Mekinist and Dabrafenib for 2 weeks only. So far, melanomas have reduced in size. Blood test results were good. Hoping it continues, but I must stress it is only early days for me. Two combined drugs are working as they should. Some nausea, aching, and itchiness. But taking antihistamines. Melanomas are in the spine, so pain is expected."

• amb...
• Taken for 6 months to 1 year
• July 17, 2023

For Melanoma, Metastatic "Stage 3 metastatic melanoma, tried Keytruda, did not work, tried Zelboraf and Cotellic, made me sick, sick, changed doctor. I am on Tafinlar and Mekinist for 7 months now. No cancer recurrence. Mild side effects include moderate dizziness, intermittent diarrhea, weight loss, intermittent nausea. Muscle fatigue and soreness. Occasional headache. No fevers. All tolerable! Clean scans!!! Most importantly, Taf 2 tablets 2 times a day, Mek 3 tablets 1 time a day. The biggest challenge is taking them on an empty stomach. I am also a type 2 diabetic. My sugars have risen quite a bit and I have had to double my metformin. That's not fun."

• Anonymous
• May 27, 2022

"Side effects for me included extreme dry skin, itching and peeling on feet, pustules on face and arms. Was on drug for 8 days, had a severe reaction. Taken off for 8 days, put on prednisone to reduce side effects. Now back on the pill, much lower dose, one tablet every other day. I have no idea if this drug will work on the tumors - I am taking Mekinist for ovarian cancer. This drug has serious side effects. I’m not sure my body will tolerate it."