Trametinib Interactions
There are 33 drugs known to interact with trametinib, along with 9 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 2 are major, and 31 are moderate.
- View all 33 medications that may interact with trametinib
- View trametinib alcohol/food interactions (1)
- View trametinib disease interactions (9)
Most frequently checked interactions
View interaction reports for trametinib and the medicines listed below.
- Abraxane (paclitaxel protein-bound)
- Acetylsalicylic Acid (aspirin)
- Adderall (amphetamine / dextroamphetamine)
- Adrenalin (epinephrine)
- Adriamycin (doxorubicin)
- Advil (ibuprofen)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Ammonul (sodium benzoate / sodium phenylacetate)
- Amphocin (amphotericin b)
- Aspir 81 (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Augmentin XR (amoxicillin / clavulanate)
- B-12 (cyanocobalamin)
- Cartia XT (diltiazem)
- Centrum Silver (multivitamin with minerals)
- Centrum Silver Men's (multivitamin with minerals)
- Co-trimoxazole (sulfamethoxazole / trimethoprim)
- Coenzyme Q10 (ubiquinone)
- Ethyl Alcohol (ethanol)
- Glycerol (glycerin)
- L-Arginine (arginine)
- Tramadol Hydrochloride ER (tramadol)
- Valproate Sodium (valproic acid)
- Viagra (sildenafil)
- Vitamin B1 (thiamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin K (phytonadione)
Trametinib alcohol/food interactions
There is 1 alcohol/food interaction with trametinib.
Trametinib disease interactions
There are 9 disease interactions with trametinib which include:
- lung toxicity
- cardiomyopathy
- GI perforation
- hemorrhage
- hepatic impairment
- hyperglycemia
- ocular toxicities
- renal impairment
- venous thromboembolism
Report options
More about trametinib
- trametinib consumer information
- Compare alternatives
- Reviews (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
