Mekinist Interactions
There are 33 drugs known to interact with Mekinist (trametinib), along with 9 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 2 are major, and 31 are moderate.
- View all 33 medications that may interact with Mekinist
- View Mekinist alcohol/food interactions (1)
- View Mekinist disease interactions (9)
Most frequently checked interactions
View interaction reports for Mekinist (trametinib) and the medicines listed below.
- alprazolam
- amlodipine
- amoxicillin
- atorvastatin
- calcium carbonate
- dexamethasone
- Eliquis (apixaban)
- Esbriet (pirfenidone)
- gabapentin
- Imbruvica (ibrutinib)
- levothyroxine
- lisinopril
- losartan
- metformin
- Nexium (esomeprazole)
- omeprazole
- ondansetron
- Opdivo (nivolumab)
- oxycodone
- pantoprazole
- prednisone
- prochlorperazine
- Promacta (eltrombopag)
- propranolol
- rosuvastatin
- sertraline
- spironolactone
- Tafinlar (dabrafenib)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
Mekinist alcohol/food interactions
There is 1 alcohol/food interaction with Mekinist (trametinib).
Mekinist disease interactions
There are 9 disease interactions with Mekinist (trametinib) which include:
- lung toxicity
- cardiomyopathy
- GI perforation
- hemorrhage
- hepatic impairment
- hyperglycemia
- ocular toxicities
- renal impairment
- venous thromboembolism
Report options
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More about Mekinist (trametinib)
- Mekinist consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (3)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
