Mekinist Drug Interactions
Currently displaying a list of 33 drugs known to interact with Mekinist (trametinib).
- 2 major drug interactions
- 31 moderate drug interactions
Medications known to interact with Mekinist
Note: Showing generic names only.
- abrocitinib
- aminolevulinic acid
- aminolevulinic acid topical
- apalutamide
- brigatinib
- chloroquine
- dabrafenib
- daprodustat
- daridorexant
- elacestrant
- elagolix
- encorafenib
- enzalutamide
- fostamatinib
- gilteritinib
- hydroxychloroquine
- idelalisib
- isavuconazonium
- lasmiditan
- methoxsalen
- methyl aminolevulinate topical
- midostaurin
- pacritinib
- pirtobrutinib
- porfimer
- pralsetinib
- pretomanid
- risdiplam
- sarecycline
- tucatinib
- vadadustat
- verteporfin
- vigabatrin
Mekinist alcohol/food interactions
There is 1 alcohol/food interaction with Mekinist (trametinib).
Mekinist disease interactions
There are 9 disease interactions with Mekinist (trametinib) which include:
- lung toxicity
- cardiomyopathy
- GI perforation
- hemorrhage
- hepatic impairment
- hyperglycemia
- ocular toxicities
- renal impairment
- venous thromboembolism
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More about Mekinist (trametinib)
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- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
