Mekinist Alternatives Compared
Mekinist | Keytruda | Tagrisso |
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Mekinist (trametinib) | Keytruda (pembrolizumab) | Tagrisso (osimertinib) |
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Prescription only
Prescribed for Melanoma - Metastatic, Thyroid Cancer, Low-Grade Glioma, Solid Tumors, Non Small Cell Lung Cancer. Mekinist may also be used for purposes not listed in this medication guide. |
Prescription only
Keytruda is an immunotherapy treatment called a checkpoint inhibitor that helps your immune system fight cancer and is used to treat many different types of cancer in adults and children including... View more |
Prescription only
Prescribed for Non Small Cell Lung Cancer. Tagrisso may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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More about Mekinist (trametinib) | More about Keytruda (pembrolizumab) | More about Tagrisso (osimertinib) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Mekinist has an average rating of 7.3 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
Keytruda has an average rating of 4.4 out of 10 from a total of 218 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 56% reported a negative effect. |
Tagrisso has an average rating of 7.3 out of 10 from a total of 36 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Mekinist side effects in more detail. |
See also: Keytruda side effects in more detail. |
See also: Tagrisso side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Mekinist prices |
View all Keytruda prices |
View all Tagrisso prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
115.2 hours |
624 hours |
48 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 20 drugs are known to interact with Mekinist:
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A total of 16 drugs are known to interact with Keytruda:
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A total of 584 drugs are known to interact with Tagrisso:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
May 29, 2013 |
N/A |
November 13, 2015 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.