Comparing Mekinist vs Tafinlar
Mekinisttrametinib |
Tafinlardabrafenib |
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Prescribed for Non-Small Cell Lung Cancer, Melanoma - Metastatic, Thyroid Cancer. Mekinist may also be used for purposes not listed in this medication guide. |
Prescribed for Melanoma - Metastatic, Non-Small Cell Lung Cancer, Thyroid Cancer. Tafinlar may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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9.0
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9.0
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Drug Class |
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Side Effects |
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Common side effects include: acneiform eruption, cardiomyopathy, decreased left ventricular ejection fraction, dermatitis, palmar-plantar erythrodysesthesia, skin rash, and erythema. See the full Mekinist side effects document. |
Common side effects include: squamous cell carcinoma, fever, and hyperglycemia. See the full Tafinlar side effects document. |
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Pricing and Coupons* Prices are without insurance |
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Generic Availability |
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No |
No |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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115.2 hours |
22 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 6 drugs are known to interact with Mekinist:
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A total of 589 drugs are known to interact with Tafinlar:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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May 29, 2013 |
May 29, 2013 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Melanoma, Metastatic Have been on Mekinist and Dabrafenib for 2 weeks only. So far melanomas have reduced in size. Blood test results were good. Hoping it continues but I must stress it is only early days for me. Two combined drugs are working as they should. Some nausea, aching and itchiness. But taking antihistamines. Melanomas are in spine so pain expected.