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Mekinist (trametinib) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with Mekinist (trametinib):


trametinib ↔ food

Moderate Food Interaction

Food may delay and reduce the absorption of trametinib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take trametinib at least 1 hour before or 2 hours after a meal.

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Mekinist (trametinib) drug Interactions

There are 7 drug interactions with Mekinist (trametinib)

Mekinist (trametinib) disease Interactions

There are 9 disease interactions with Mekinist (trametinib) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.