Drug interactions between Mekinist and Tafinlar
Interactions between your drugs
- Mekinist is in the drug class multikinase inhibitors.
- Mekinist is used to treat Melanoma, Metastatic.
- Tafinlar is a member of the drug class multikinase inhibitors.
- Tafinlar is used to treat Melanoma, Metastatic.
Drug and food interactions
Applies to: Tafinlar (dabrafenib)
Food may delay and reduce the absorption of dabrafenib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take dabrafenib at least 1 hour before or 2 hours after a meal.
Applies to: Mekinist (trametinib)
Food may delay and reduce the absorption of trametinib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take trametinib at least 1 hour before or 2 hours after a meal.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
The recommended maximum number of medicines in the 'multikinase inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'multikinase inhibitors' category:
- trametinib (active ingredient in Mekinist (trametinib))
- dabrafenib (active ingredient in Tafinlar (dabrafenib))
Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.
Drug Interaction Classification
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Do not stop taking any medications without consulting your healthcare provider.