Cotellic Interactions
There are 403 drugs known to interact with Cotellic (cobimetinib), along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 124 are major, and 279 are moderate.
- View all 403 medications that may interact with Cotellic
- View Cotellic alcohol/food interactions (1)
- View Cotellic disease interactions (7)
Most frequently checked interactions
View interaction reports for Cotellic (cobimetinib) and the medicines listed below.
- Actemra (tocilizumab)
- Adcetris (brentuximab)
- Aspirin Low Strength (aspirin)
- atorvastatin
- Biaxin (clarithromycin)
- bleomycin
- Blincyto (blinatumomab)
- Bosulif (bosutinib)
- Cosentyx (secukinumab)
- Eltroxin (levothyroxine)
- Esbriet (pirfenidone)
- Imbruvica (ibrutinib)
- Kalydeco (ivacaftor)
- Kynamro (mipomersen)
- Lyrica (pregabalin)
- Mekinist (trametinib)
- metformin
- Nexium (esomeprazole)
- Nydrazid (isoniazid)
- Oncovin (vincristine)
- Procysbi (cysteamine)
- Promacta (eltrombopag)
- Sabril (vigabatrin)
- Sandimmune (cyclosporine)
- Stribild (cobicistat / elvitegravir / emtricitabine / tenofovir disoproxil)
- Tafinlar (dabrafenib)
- tamsulosin
- Tecentriq (atezolizumab)
- Trecator-SC (ethionamide)
- Zelboraf (vemurafenib)
Cotellic alcohol/food interactions
There is 1 alcohol/food interaction with Cotellic (cobimetinib).
Cotellic disease interactions
There are 7 disease interactions with Cotellic (cobimetinib) which include:
- cardiomyopathy
- hepatotoxicity
- ocular toxicities
- rhabdomyolysis
- lung toxicity
- liver dysfunction
- renal impairment
Report options
More about Cotellic (cobimetinib)
- Cotellic consumer information
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
