Cotellic Interactions
There are 401 drugs known to interact with Cotellic (cobimetinib), along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 124 are major, and 277 are moderate.
- View all 401 medications that may interact with Cotellic
- View Cotellic alcohol/food interactions (1)
- View Cotellic disease interactions (7)
Most frequently checked interactions
View interaction reports for Cotellic (cobimetinib) and the medicines listed below.
- Actemra (tocilizumab)
- Adcetris (brentuximab)
- Aspirin Low Strength (aspirin)
- atorvastatin
- Biaxin (clarithromycin)
- bleomycin
- Blincyto (blinatumomab)
- Bosulif (bosutinib)
- Cosentyx (secukinumab)
- Eltroxin (levothyroxine)
- Esbriet (pirfenidone)
- Imbruvica (ibrutinib)
- Kalydeco (ivacaftor)
- Kynamro (mipomersen)
- Lyrica (pregabalin)
- Mekinist (trametinib)
- metformin
- Nexium (esomeprazole)
- Nydrazid (isoniazid)
- Oncovin (vincristine)
- Procysbi (cysteamine)
- Promacta (eltrombopag)
- Sabril (vigabatrin)
- Sandimmune (cyclosporine)
- Stribild (cobicistat / elvitegravir / emtricitabine / tenofovir disoproxil)
- Tafinlar (dabrafenib)
- tamsulosin
- Tecentriq (atezolizumab)
- Trecator-SC (ethionamide)
- Zelboraf (vemurafenib)
Cotellic alcohol/food interactions
There is 1 alcohol/food interaction with Cotellic (cobimetinib).
Cotellic disease interactions
There are 7 disease interactions with Cotellic (cobimetinib) which include:
- cardiomyopathy
- hepatotoxicity
- ocular toxicities
- rhabdomyolysis
- lung toxicity
- liver dysfunction
- renal impairment
Report options
More about Cotellic (cobimetinib)
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- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: multikinase inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Cosentyx
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Yervoy
Yervoy (ipilimumab) is a cancer treatment used for lung cancer, melanoma, renal cell carcinoma ...
Tafinlar
Tafinlar is a prescription medicine used to treat BRAF mutated melanoma, non-small cell lung ...
Braftovi
Braftovi is a targeted cancer treatment used in combination with Mektovi, mFOLFOX6, or Erbitux, to ...
Dacarbazine
Dacarbazine is used for hodgkin's lymphoma, melanoma, melanoma, metastatic
Ipilimumab
ipilimumab (Yervoy) is an immunotherapy used for melanoma, renal cell carcinoma, non-small cell ...
Dabrafenib
Dabrafenib is used for low-grade glioma, melanoma, metastatic, non small cell lung cancer, solid ...
Trametinib
Trametinib is used for low-grade glioma, melanoma, metastatic, non small cell lung cancer, solid ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
