Cotellic Alternatives Compared
Cotellic | Yervoy | Mekinist |
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Cotellic (cobimetinib) | Yervoy (ipilimumab) | Mekinist (trametinib) |
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Prescription only
Prescribed for Histiocytic Neoplasm, Melanoma - Metastatic. Cotellic may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Melanoma, Colorectal Cancer, Renal Cell Carcinoma, Malignant Pleural Mesothelioma, Melanoma - Metastatic. Yervoy may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Melanoma - Metastatic, Solid Tumors, Thyroid Cancer, Low-Grade Glioma, Non-Small Cell Lung Cancer. Mekinist may also be used for purposes not listed in this medication guide. |
Related suggestions Melanoma, Metastatic
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More about Cotellic (cobimetinib) | More about Yervoy (ipilimumab) | More about Mekinist (trametinib) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Be the first to share your experience with this drug. |
Yervoy has an average rating of 9.5 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Mekinist has an average rating of 7.3 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Cotellic side effects in more detail. |
See also: Yervoy side effects in more detail. |
See also: Mekinist side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Cotellic prices |
View all Yervoy prices |
View all Mekinist prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
44 hours |
352.8 hours |
115.2 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 368 drugs are known to interact with Cotellic:
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A total of 152 drugs are known to interact with Yervoy:
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A total of 20 drugs are known to interact with Mekinist:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
November 10, 2015 |
March 25, 2011 |
May 29, 2013 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.