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Vilazodone Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Vilazodone Vraylar Wellbutrin XL
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Vilazodone Vraylar (cariprazine) Wellbutrin XL (bupropion)
Prescription only

Prescribed for Major Depressive Disorder, Anxiety, Obsessive Compulsive Disorder, Depression. vilazodone may also be used for purposes not listed in this medication guide.

Prescription only

Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more

Prescription only

Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide.

Related suggestions

Major Depressive Disorder
More about Vilazodone More about Vraylar (cariprazine) More about Wellbutrin XL (bupropion)
Ratings & Reviews

Vilazodone has an average rating of 5.8 out of 10 from a total of 976 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 35% reported a negative effect.

Vraylar has an average rating of 5.9 out of 10 from a total of 490 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 35% reported a negative effect.

Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 487 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect.

View all 976 reviews

View all 490 reviews

View all 487 reviews

Drug Class
Side Effects

See also: vilazodone side effects in more detail.

See also: Vraylar side effects in more detail.

See also: Wellbutrin XL side effects in more detail.
Generic Availability

Lower cost generic

No lower cost generic approved

Lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 30 tablet
Dosage 10 mg
Per Unit* $3.19 - $10.50
Cost* $95.55 - $314.88

View all vilazodone prices

Quantity 20 each
Dosage 1.5 mg
Per Unit* $51.25
Cost* $1,024.98

View all Vraylar prices

Quantity 30 tablet, extended release
Dosage 150 mg/24 hours
Per Unit* $70.42
Cost* $2,112.52

View all Wellbutrin XL prices

Get free Discount Card

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Dosage Forms Available
  • Oral tablet
  • Oral capsule
  • Oral tablet, extended release
Brand Names
Viibryd

N/A

 Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

25 hours

504 hours

30 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 429 drugs are known to interact with vilazodone:

  • 114 major drug interactions (477 brand and generic names)
  • 312 moderate drug interactions (1180 brand and generic names)
  • 3 minor drug interactions (7 brand and generic names)

A total of 570 drugs are known to interact with Vraylar:

  • 93 major drug interactions (380 brand and generic names)
  • 476 moderate drug interactions (1808 brand and generic names)
  • 1 minor drug interactions (3 brand and generic names)

A total of 520 drugs are known to interact with Wellbutrin XL:

  • 218 major drug interactions (955 brand and generic names)
  • 297 moderate drug interactions (1345 brand and generic names)
  • 5 minor drug interactions (16 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Do not drink alcohol while you are taking vilazodone. It can increase some of the side effects... View more
  • Grapefruit juice can increase the blood levels of cariprazine. This may increase side effects such... View more
  • Using cariprazine together with alcohol may increase side effects such as dizziness, drowsiness... View more
  • Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures... View more
Disease Interactions
First Approval Date

January 21, 2011

N/A

August 28, 2003
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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