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User Reviews for Vilazodone

Also known as: Viibryd

Vilazodone has an average rating of 5.9 out of 10 from a total of 852 ratings on Drugs.com. 46% of those users who reviewed Vilazodone reported a positive effect, while 35% reported a negative effect.

Condition Avg. Rating Reviews Compare
Depression  
6.0
588 reviews 78 medications
Major Depressive Disorder  
5.4
195 reviews 47 medications
Anxiety  Off-label
6.1
60 reviews 53 medications
Obsessive Compulsive Disorder  Off-label
4.6
9 reviews 11 medications
Summary of Vilazodone reviews 5.9 852 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Vilazodone

qilathe · Taken for 2 to 5 years June 5, 2021

For Obsessive Compulsive Disorder: “I have tried a couple different medications for my OCD, and Viibryd helps with no practical side effects, at least is has less side effects than any other medication I have taken for before. I just very mild GI stuff. Was recommended by my doctor based on some research at the time. For me, it is extremely helpful, I cannot put on words how helpful. I take the 20 mg/day dosage.”

10 / 10
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Bob_FL · Taken for 1 to 6 months June 1, 2021

Viibryd (vilazodone) for Major Depressive Disorder: “Have been on SSRI's since 1992. Then switched to SNRI Pristiq for 7 years, but it "pooped out." Tried Trintellix, Cymbalta for 6 months and was always falling asleep at my desk and absolutely knocked-out all libido. Did a cross-switch to Viibryd which is the best med so far. It's an SSRI, but it uses a different pathway, and I feel like myself again. Since there's no generic, it is expensive, but worth every penny. Libido is back! No more ED or need for Viagra at 65 years old. That certainly helps to feel "whole" again. Did the cross-switch from Cymbalta to Viibryd and it wasn't very difficult by slowly decreasing Cymbalta and gradually increasing Viibryd. Went from 10-20-30 with no problem. Just started 40mg which is recommended dose. Also, 25mg of Staterra was added for concentration (ADHD). Feeling great - results excellent.”

10 / 10
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A0052 · Taken for 6 months to 1 year May 11, 2021

For Anxiety: “I have panic disorder that has been managed for years and depression. Definitely some GAD and reactive to stress, but this is part of my job. Having taken numerous medications over 25+ years Viibryd at 20mg has made a huge difference always tried to stay away from SSRIs, emotional blunting and sexual side effects. Viibryd does not give me sexual side effects and helps manage anxiety. A very good and effective medication for me. It took 4-6 weeks to get all the positive effects.”

9 / 10
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Frequently asked questions

Anonymous September 7, 2011

Viibryd (vilazodone) for Depression: “I have had a lot of additional stress added in the last 4 years... death of a parent, a lot of hurtful things from my other parent, my spouse cheating, then everyday things like the stresses of young children, school, sports, etc. Over these years I have tried every antidepressant out there! It either didn't work, or it made me feel like a zombie. And they ALWAYS made my sex drive go to zero! I had given up on every prescription and had not taken anything for almost a year. I had no energy, it didn't take much for me to get annoyed and aggravated with people (including my kids) and I just didn't feel a lot of joy. My doctor tried me on Viibryd and I feel GREAT! I have great energy, don't lose my temper with my kids or husband, and still have sex drive!”

10 / 10
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JG · Taken for 1 to 6 months March 9, 2020

Viibryd (vilazodone) for Depression: “I had been on Lexapro for ~3 years and it was losing it's effectiveness and I was falling into a deep malaise from it. Doc switched me to Trintellix first - and it worked well - BUT I was unbearably dizzy from it. So, I switched to Viibryd and it has been great so far. Felt better immediately on the 10mg taper and have been stable at 20mg for about 2 months now and really like it. Knocks my anxiety down to almost zero, but I have way more energy, focus, feelings than I did on Lexapro. It is super expensive, even with my good insurance and their discount card, but it is worth it to me at this point. Hope this review helps someone”

10 / 10
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Anonymous September 7, 2011

Viibryd (vilazodone) for Depression: “I have atypical depression. I have tried Wellbutrin (allergic reaction), Zoloft (diarrhea, anxiety), Prozac (good experience), and Effexor, which made me crave alcohol everyday even though I generally dislike alcohol and am not a regular drinker. All of these gave me delayed ejaculation problems except for the Wellbutrin. I pretty much gave up on medicines until I had a major depressive bout and went back to the psychiatrist who suggested I give Viibryd a try. It has made everything so much better! No side effects, high energy and motivation, and has stabilized my usually volatile temper greatly. I've read a lot of negative reviews out there so I was compelled to write this review because in my case, rare as it may be, Viibrys has worked.”

9 / 10
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Marie H. September 2, 2020

Viibryd (vilazodone) for Depression: “I have had issues with MDD and GAD for years, I was originally put on Lexapro and I quickly noticed a difference. I no longer felt depressed or hopeless but I was tired all the time with little energy to do anything. After 6+ months I went on Wellbutrin few days and was paranoid and on edge! I was put on Viibryd 10 mg for 1 week and 20 mg after that once per day. Initially the side effects were nausea, stomach pain, diarrhea, drowsiness, and headaches. I stuck it out for 2 weeks like that. I began taking my meds at night instead of am, initial side effects went away and I was able to sleep well, eat normal, and had energy to do things that I enjoyed. My focus and mood improved so much my husband noticed instantly. This is one of the meds with least sexual side effects, I was still able to continue with my sex life with few issues. make sure to take your meds on time, a missed dose will quickly cause withdrawal symptoms like nausea, headaches, and irritability.”

8 / 10
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More FAQ

Manda February 26, 2020

Viibryd (vilazodone) for Depression: “I've never written a review on a drug before, but felt compelled to do so with this one. I've struggled with depression my whole life. Was on Wellbutrin for many years before my hysterectomy. After my hysterectomy, I fell into a very deep depression, even when on my Wellbutrin. I couldn't get out of bed, slept all the time, was withdrawn, etc. My doctor started me in 10 mg Viibryd for 2 weeks then we moved up to 20 mg. At 20mg dose I was so sleepy so we kept it at 10 mg. I feel like a new person!! I'm stable, level, happy, can handle situations calmly... it literally saved my life. My sex drive seems to have gone down dramatically, but I will try to deal with that the best I can. Being happy and not crying all the time is worth me having to put more effort into the sex drive part. I think part of that could be due to the hysterectomy also. I'm truly grateful to have my life back.”

10 / 10
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Anonymous October 24, 2011

Viibryd (vilazodone) for Depression: “I have been on Zoloft, Wellbutrin, and Celexa. Struggling with depression for years, but Viibryd really has been the "panacea". It manages all of my symptoms and gives me energy like none of the other medications could. It's definitely different from other antidepressants and for some who experience some difficult startup syndrome, PLEASE stick with it for a few weeks. I've heard of a lot of people who had a difficult startup with this medication and the switch was just flipped one day out of the blue. Viibryd really is an improvement from other antidepressants and I encourage all to give it a try.”

10 / 10
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ChrisDDD September 11, 2011

Viibryd (vilazodone) for Depression: “I am finishing my 4th week of Viibryd. I'm afraid to jinx myself by saying this, but I feel I have my old life back again. The reality of being on an anti-depressant (Viibryd) and being MORE sexual MORE quickly is heaven to me! I have renewed hopes about a future I never thought I'd see. My last marriage ended because of Zoloft, Effexor, you name it, and hard to date, too, and explain why nothing's working and it isn't going to work. Please keep working, Viibryd!! My only side effect has been two nights of terrifying nightmares. I'll take those any day over not being able to be a complete woman.”

9 / 10
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Harpguy · Taken for 1 to 6 months January 26, 2020

Viibryd (vilazodone) for Depression: “I have been on multiple medications for depression my entire life. Some don’t work at all; some cause side effects that are unbearable. Viibryd does neither. For the first time ever, I can honestly say that I am now learning how to live without the horrible effects of depression. I am happier, much more social, and am experiencing better moods than I ever have. This medication has literally been life changing for me. I have experienced no side effects at all. All in all, I cannot say enough good things to emphasize how much this med has changed my life for the good!”

10 / 10
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Bazzle · Taken for 1 to 6 months May 31, 2020

Viibryd (vilazodone) for Major Depressive Disorder: “Well, Viibryd. What to say, from looking at the general response it either works amazingly or the side effects can be debilitating. As for my experience? This has been a wonderful drug. I have not had gene sight testing (I wish I had) but have gone through the general ringer with the old fashioned trial and error. No other SSRI/SNRI/DNRI/TCA has worked for me but Viibryd has! I totally disagree that 20mg is the optimal dose it’s all subjective, 20mg worked for me for 3 weeks then completely pooped out. Now up to 40mg and two days in and I feel great. So if it makes stops working and you feel it had worked prior, do not be afraid to increase after talking to your DR vs stop taking. But yes there are side effects- diarrhea (which went away) & headaches , increased RLS being the mainstay but tolerable. And my sex life has greatly improved on this drug. I give it a ten out of ten. FYI - I take Gabapentin For the RLS at night which helped immensely. Good luck. God speed.”

10 / 10
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Honest Reviewer · Taken for 1 to 6 months January 12, 2021

Viibryd (vilazodone) for Depression: “I hate to write negative reviews, but I feel that it's important to do so with this medication. Based upon other reviewers, and my own experience, I feel that something is inherently "wrong" with Viibryd. I may have noticed a slight elevation of my mood when I began taking it; but over time, the side effects such as nausea, indigestion, and a general feeling of malaise gradually took center stage. I finally tapered off and discontinued usage, and I feel sooo much better now! In hindsight, I had been feeling miserable for about 4 or 5 months! For reference, I am 55 yrs. old, active, 150 lbs, bipolar II with depression, and take Trazadone, Buspar, and Lamictal. I have a graduate degree, see my doc every three months, and take all meds as prescribed and with food......Viibryd, has probably the worst medicine that I've ever been on..................”

1 / 10
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Anonymous April 16, 2021

Viibryd (vilazodone) for Major Depressive Disorder: “I’ve been through countless medications - I have anxiety, panic attacks, mdd. They all made me sick, more anxious, panic attacks that felt like heart attacks, have aggressive behavior, bouts of OCD, RLS, feel like I was walking in a fog, etc. Viibryd has been tolerable. I don’t feel as depressed and overwhelmed to the point of feeling paralyzed. Only side effect is vivid nightmares, and really not helping with my anxiety/panic attacks. As long as I am still prescribed my Xanax, my whole life feels so much better. The Xanax helps with the panic and anxiety, but the depression was always lingering and interfering with my day to day life, and viibryd is taking care of that. Thank goodness I finally found a doctor that listens!!! I would much rather deal with nightmares than the deep dark depression I’ve been in for years.”

9 / 10
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Anonymous August 18, 2011

Viibryd (vilazodone) for Depression: “No side effects. Relief of symptoms of depression was evident in the first week of taking this medication and are continuing. The medication is expensive ($200 for a month's supply), but a small price to pay for what it delivers.”

10 / 10
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Hankley May 5, 2020

Viibryd (vilazodone) for Depression: “Switched to Viibryd about a year ago to treat an anxiety disorder and depression. Was on Lexapro originally, but it was making me too sleepy to function. Starting out, I got nauseated around the time I took a dose (used the pack to scale from 0-20mg over time). That stopped after a few days though. I do still get periods of dizziness right around the time I take my dose though. I've stayed on 20mg for the last year, and haven't felt the need to change anything med wise. I feel a lot more in control of myself on Viibryd, and I generally don't spiral when I'm on the pill. Really helped to manage anxiety/depression, while keeping me at a normal energy level.”

8 / 10
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draesq March 25, 2014

Viibryd (vilazodone) for Depression: “I am at the end of the 2nd week of the starter pack, last 20 mg pill. I feel so much better on this medicine. My depression started after some horrible things happened in my family and it paralyzed me. I didn't want to do anything anymore. I wanted to be left alone. I finally feel happy again. I have been on Zoloft. That worked but I gained too much weight. Effexor didn't really help and Wellbutrin did nothing. This one made a huge difference and quickly. I had diarrhea the first day of each new dose but it quickly went away. No other side effects. I am also sleeping much better. The bottom line is, everyone is so completely different. It is all trial and error.”

10 / 10
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45/male/married w/children · Taken for 2 to 5 years March 11, 2014

Viibryd (vilazodone) for Depression: “This medication simply saved my life. Addiction took me down a dangerous path - hiding bottles, attempting to obtain more prescription pain killers, doing it all at night to hide from wife/kids...long dark road for sure. 30 days intensive recovery in a facility, away from everyone just for me, AA meeting and my doctor put me on anti-depressants that just made me groggy, disoriented and volatile at times. Changed a few times till we hit Viibryd. Absolutely amazing from the first few days. 40mg and sometimes a tad more when the waves of irrationality come. Mostly even sailing. Life is enjoyable, work is productive and I am totally plugged back into everyone's life at home. No issues with side effects at all.”

10 / 10
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Momzilla October 4, 2011

Viibryd (vilazodone) for Depression: “My doctor told me to eat lots of protein in the morning. The protein attaches to the active ingredient in the Viibryd. He said the worst side effects of this medicine would be nausea and diarrhea. He told me to eat the equivalent of an Egg McMuffin in the morning with my medicine. I'm up to 10mg and I eat 30-40gm of protein with it. I do have diarrhea, but I'm hopeful that it will go away once my body is accustomed to the new protein requirement. I'm a cereal lover. Eggs, ham and cheese are too much in the mornings some days, but I'm willing to do this because I feel so much better on this medication. I'm not snappy and I seem to have more energy.”

9 / 10
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AnxietyRelief · Taken for 6 months to 1 year July 7, 2019

Viibryd (vilazodone) for Depression: “Thankful for this medication. I have been on it for a year now, working my way up to 40mg but I can’t explain how well this medication has worked and how good I feel. Very thankful. I am a RN and it is okay to take medication, please don’t ever be ashamed. Finding the right med will help you dramatically. Please get genetic testing done to see what med will work with your body. I tried all of the most common SSRIs and none helped/turns out none of them were compatible with my body. Viibryd was the first med since my genetic testing results came back that I’ve been on and it’s a match. Such a blessing of how good I feel. Praying for all. God bless.”

10 / 10
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ac1 January 31, 2012

Viibryd (vilazodone) for Depression: “Been on Viibryd for several months, have tried other medications in past but sexual side effects were too bad. When I started Viibryd I had been depressed for several months, found myself more withdrawn, low energy, unsocial, and unmotivated. Since then I have felt like a new person only side effect was stomach issues during the first week. I now have lots of energy, very social, and motivated. I would recommend this to anyone considering an antidepressant and wants to avoid the sexual side effects. In my opinion A . ”

10 / 10
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Anonymous August 8, 2011

Viibryd (vilazodone) for Anxiety: “I have been on other anxiety medicines, which only added to my blood pressure spiking, but with Viibryd, my blood pressure has dropped down to normal readings, for example, 110/74, and I have the energy level I had before trying all of the other medicines. I highly recommend this medicine.”

10 / 10
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Ambwee · Taken for 1 to 6 months March 2, 2014

Viibryd (vilazodone) for Depression: “I've been on so many anti depressants. I can't even tell you how many I've tried and none of them had any effect or very little. My doctor started me out on sample pack of Viibryd and gave me a few packs of the 40mg to last me until she gets back from out of the country. I've been on it for a month now and it's been amazing. I have schizoaffective disorder with major depression, panic disorder and post traumatic stress disorder. Viibyrd is amazing. I feel so much better already. I never got any of the side effects other people experienced. It's been nothing but pleasant for me. My mood, energy, everything has gotten so much higher than it has been in years. I'm so excited about my future now. I have so many dreams that I feel like I can now accomplish and I'm very optimistic now.”

10 / 10
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Neonurse12 October 4, 2020

Viibryd (vilazodone) for Depression: “I’ve been on several medications for anxiety/depression. I get severe severe anxiety with occasional depression. When I first started Viibryd I was extremely irritable and constantly crying. I stuck it out for a while (at the time I was too depressed to go to the doctor to fix it) and it ended up getting a lot better. The side effects went away and I was okay. I’ve been on Viibryd for about 2 years now and I would say the worst side effect is the sleep issues. I work third shift and I generally take it in the morning (around 7:30am) when I get home from work. If I don’t take it around that time on my days off, I feel like I’m in a coma and can’t get up. I’m like sleeping, but aware. And I feel like I’m constantly trying to drag myself out of bed and it takes several tries before I feel that my mind is strong enough. Then when I get up and take it, I have a headache almost all day. If I take it at the exact time daily, it’s a pretty good drug. I hope all this makes sense!”

7 / 10
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Rb · Taken for less than 1 month January 1, 2020

Viibryd (vilazodone) for Depression: “My 34 y/o sister was prescribed Viibryd for depression. On week 2 she had a major stroke. She died two days later. She didn’t have any health issues or heart problems besides depression and was not taken any other medications. She was a single mother working full time. We don’t even have a family history of strokes. It’s hard to say for sure that Viibryd caused the stroke; but after reading all the possible side effects, interactions, and reviews. I’m convinced. I just wanted to write a review so that the people prescribed it will be aware and cautious.”

1 / 10
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Steve55 · Taken for less than 1 month October 7, 2018

Viibryd (vilazodone) for Depression: “ I’m a man and I could almost cry based on how well this medication has made me. I tried so many meds with no success, I even tried ketamine infusions. I’ve tried antipsychotics too. Nothing was working until Viibryd. I’ve had 100% improvement within 1 week on only 10mg. Amazing! I’m thankful, I’m grateful, and I’m blessed.”

10 / 10
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Lizsmiles · Taken for 1 to 6 months February 24, 2014

Viibryd (vilazodone) for Depression: “Viibryd has honestly changed my life for the better. I've had depression and anxiety for 5 years. I was going to therapy (and I still do), but it was recommended I try some medication because I was not really feeling any better and I was very hesitant. I did 5mg for 2 weeks, 10mg for a week, 20mg for a week, and now I'm on 40mg. I experience NO side effects. No diarrhea or nausea like most people have at the beginning. Not only did my anxiety come under control when I started the 20mg, but I feel happy now. My sex drive has been normal and I've actually lost weight since I started Viibryd since I don't have the urge to eat everything now. It's definitely worth a try.”

10 / 10
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Cert Barfly, Ph.D. August 30, 2011

Viibryd (vilazodone) for Depression: “Whatever it takes get on Viibryd today. Talk your doctor into a diagnosis that meets the general indication for this medicine and watch all your symptoms (real, imagined, and subtly feigned) of depression, anxiety, and many other axis 1 psychiatric disorders disappear like magic. Viibryd is totally awesome.”

10 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.