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Vilazodone User Reviews & Ratings (Page 5)

Brand names: Viibryd

Vilazodone has an average rating of 5.9 out of 10 from a total of 990 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Vilazodone

Commonly mentioned side effects
  • Cha...
  • January 11, 2013

Vilazodone for Depression "I have tried almost every antidepressant out there in the last 20 years. Wellbutrin, Effexor, Prozac, Zoloft, and a few I can't remember with little to no effect. Viibryd has been the absolute best and made a huge difference. Life is much more enjoyable, and I have a lot more energy, actually wanting to get out and do things again. My irritability has gone way down. Another great thing is it doesn't decrease your sex drive at all, if anything, it has increased because I feel so much better."

10 / 10
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  • jkg...
  • May 27, 2013

Vilazodone for Depression "This medication has worked wonders for me. After reading the side effect reviews from others, I was worried. However, I made sure I ate a good protein breakfast with the medicine. I used the starter pack which ramps up the dosage slowly. I only had minor side effects and those lasted just a few days. I feel so much better now and am so glad I decided to take a chance with Viibryd. The biggest plus is no weight gain, which is common with other medicines for this condition."

10 / 10
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  • Ant...
  • Taken for 1 to 6 months
  • May 29, 2015

Vilazodone for Depression "I have been experiencing increasing anxiety the more I progress into menopause. Tried Cymbalta and it made me so drowsy that I was afraid of falling asleep while driving. Started on Viibryd about 2 months ago and I feel fabulous. My anxiety is totally under control, and I have the energy to go out and do things. Recently lost 5 pounds because I had the energy to work in the yard. There has been some diarrhea, but it does not bother me as the benefits are such a difference in how I feel."

10 / 10
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Frequently asked questions

  • Nig...
  • Taken for 6 months to 1 year
  • April 24, 2025

For Anxiety "So I take this medicine for a list of reasons. I’m at 40 mg. When I first started taking it, I had horrible night sweats and absolutely terrible, realistic dreams. I would wake up not knowing where I was. Hear me out, I stuck to it… it took three months and boom, all normal again. I feel so free and so normal, and for the first time in my life with this med and some others, I finally can say I’m actually happy. I’m now engaged and planning my wedding… the only downside is I take it at night and I think it keeps me up from sleeping. Sometimes it makes me dream out of body. I’ll laugh randomly while I’m trying to sleep. It’s a small price to pay to finally feel in control. Hope that helps someone feel less alone on their journey."

9 / 10
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  • 1st...
  • May 14, 2013

Vilazodone for Depression "I've been on Viibryd 20mg for 18 months. My doctor suggested staying at 20mg at my follow-up appointments because that dose currently works for my depression and mood changes. I still have to take it with a snack due to mild nausea. I don't like the abdominal distention (especially with PMS). I recently noticed memory problems and mixing up my words. Despite all that, I'm not going to stop Viibryd because I was an emotional mess 18 months ago. Celexa and 'other' meds left me dull and in a haze. Now, I can cope better and feel more like me!"

9 / 10
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  • She...
  • Taken for 1 to 2 years
  • January 11, 2015

Vilazodone for Major Depressive Disorder "I experienced some side effects in the beginning of taking this medication. I tried two others prior to this and they failed so when I got onto this, it helped me so much. I feel so much better and more energized than I have had in the past."

9 / 10
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  • Swe...
  • February 18, 2013

Vilazodone for Depression "I've been in chronic pain with chronic fatigue for 30 plus years: fibromyalgia and CFS. This caused many years of depression. Took other SSRI's over the years but was always teetering on the side of depression. Cymbalta did nothing for me except weight gain. My Dr. gave me a trial pack of Viibryd. When I started the 40 mg, I experienced severe GI upsets... heartburn, growls & grumbling, gas, & nasty taste on my tongue. I also had vividly violent dreams as soon as I fell asleep. I reported these complaints to my Dr. and he lowered my dosage to 20 mg. I still have a little gas and a violent dream every once in a while, but my depression & energy are so much better. I feel like 'me' again. I definitely recommend giving Viibryd a try."

8 / 10
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  • Vii...
  • Taken for 1 to 6 months
  • December 19, 2022

Vilazodone for Depression "Terrible. Anger, hostility, sadness, irritability, self-loathing, lashing out at innocent family members, the list goes on. These symptoms got progressively worse. DO NOT WAIT! If you are feeling any of these things, even mildly, get off of this stuff immediately. It will only get worse."

1 / 10
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  • Anonymous
  • February 12, 2014

Vilazodone for Depression "In 3 days, I felt better. Titrated to 40 mg. The medicine turned evil. My heart pounding with strong palpitations. As I was falling asleep, I had a feeling of leaving my body & hovering over myself, being awake in a horrifying world that seemed absolutely real. Sleep paralysis. Dr. added a beta-blocker for the heart. Gained 21 lbs in 6 wks. Decided to stop it. Dr. said go from 40-20. I couldn't do that suddenly, I needed to go down slowly. I went from 40-30 mg. Night terrors lessened. Went to 25, then 20. Felt good at 20, heart calmed down for a few days. Thought I'd stay at 20 but then the evil again. 18, 15, 10, 5, 3 mg. It's taken over a month to come off it. 1st day without it. Feel down & edgy. Started Wellbutrin."

1 / 10
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  • Wen...
  • September 28, 2011

Vilazodone for Depression "I'm so happy to see that many people have had positive results from this medication. I was on it for 5 days and had diarrhea so bad I had to stop. I lost 5 pounds in 2 days (granted I'd like to lose a few, but not like that). I've been off it for 1 day now, and I'm still running to the bathroom (it's not as bad, but painful). I wish I would have had the experience others have had. But this drug just isn't for me. Unfortunately, it seems that most antidepressants cause a number of side effects for me. Keeping me stable is a challenge. (I have bipolar disorder)."

2 / 10
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  • Ted...
  • Taken for 1 to 2 years
  • October 1, 2013

Vilazodone for Anxiety "Been on antidepressants since around 1991 after I had thyroid removed. Taking Wellbutrin for depression, which works okay, but last year started having late-night anxiety attacks. Really bad fear. I don't understand why. Had me walking the streets at 11 PM. Started Viibryd and had weight gain and stomach issues, and by the time I got to 40 mg, the anxiety just stopped! This medicine does as advertised for me, it stops the anxiety. That's what I needed, and that's what I got. Like a miracle."

9 / 10
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  • Try...
  • Taken for 1 to 2 years
  • September 1, 2014

Vilazodone for Depression "I am taking it for anxiety, depression, and obsessive-compulsive disorder intrusive thoughts. This medicine worked really quickly, between 40mg of this, 5mg of Abilify with therapy, it helped a lot! However, after a year, it stopped working for me. So I was switched to something else. Good luck, everyone. It's a good medicine."

8 / 10
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  • cal...
  • Taken for 1 to 6 months
  • February 23, 2020

Vilazodone for Depression "Viibryd was okay for the first week. I felt a little better, and I wasn't having any side effects. When I upped my dose (I think from 10 mg to 20 mg?), I started to feel really good, like at peace with myself and the world around me for maybe the first time ever. It was awesome. I thought I had found the answer, but things went downhill by week 3. I developed a sexual dysfunction that got continually worse (libido intact, but unable to achieve orgasm; beyond frustrating). That was followed by a zombie-like effect that became the new me. I felt like I was an avatar walking through my life controlled by the real me, who was a few blocks over having a panic attack that didn't matter because nothing did, and that was fine by me. By the end of the fifth week, a friend who is experienced with SSRIs took me aside and had an intervention: it's not supposed to be like this; get on something else. I'm now on Trintellex; much lighter, much better for me."

2 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • December 10, 2015

Vilazodone for Depression "I have been taking this medicine for three years now. I have tried every antidepressant out there, I think. This is the only one that works for me. Along with Abilify and Trazodone, this has been a miracle worker for me. I have no side effects. The Trazodone helps with sleep and no nightmares. I wouldn't be around if it wasn't for Viibryd."

10 / 10
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  • -aa...
  • Taken for 6 months to 1 year
  • August 11, 2019

Vilazodone for Depression "I first started Viibryd about a year ago after my depression and anxiety started taking control of my life. I started on the 10 mg tablets and increased to 20 mg after 7 days. After much difficulty with insurance and trying many other medications, we got it approved. I have very few side effects, but if I miss a dose (I take them at night before bed), the next morning I wake up groggy and very irritable. I like this drug because it has had little to no effect on libido. My confidence has also greatly increased now that my anxiety is manageable. Overall, I would personally recommend it. This is a miracle drug for real."

9 / 10
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  • Lea...
  • Taken for less than 1 month
  • June 13, 2013

Vilazodone for Depression "The reason for the 7 is because I just started taking this medication and am getting ready to take my first 20mg pill in the starter pack I got from the doctor. I took the week's worth of 10mg and so far the only side effect I've had is bad night sweats. I noticed a difference almost right away in taking this medication. Things didn't seem so bleak, I stopped crying and started laughing and smiling again. I have a LOT of energy and feel like doing things again. I am hopeful, starting the 20mg doesn't give me too many more side effects because as of right now I am SO glad I started taking this because it has literally given me my life back. I've tried Celexa and all that did was make me a zombie so this is GREAT!"

7 / 10
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  • Ale...
  • Taken for 1 to 6 months
  • September 19, 2018

Vilazodone for Depression "I am a senior citizen that has been on Viibryd for one month. This drug has been awesome for me. The only side effects were very slight nausea the first week and loose stool on day one. I'm on 20 mg, and I have never felt better in many, many, many years. I would highly recommend this drug, and also I take it exactly according to directions. I am taking it right after breakfast, and I just feel wonderful."

10 / 10
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  • Sha...
  • Taken for 1 to 6 months
  • December 28, 2023

Vilazodone for Depression "I've tried many antidepressants over the years. At 42, I finally found one that's changed my life, and that's Viibryd. I had zero side effects except for increased intestinal motility, which did not lead to diarrhea like many others report. I have chronic constipation since I was a kid, obviously...that's where 90% of serotonin is made, which is why I have depression (go read about that). I have had ZERO negative side effects. Libido, orgasm...no issues. This medicine has changed my life. I always dreamt and wondered what it was like to feel the way I feel now. I'm four months in, up to 20mg, didn't need to increase to 40mg because of my success on the 20mg. If I'm an hour or two late taking it, I feel nothing adverse like others report. This has been a life-changing med for me personally. Good luck to anyone who is on their journey to a happier life. This was my godsend!"

10 / 10
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  • Ran...
  • Taken for 6 months to 1 year
  • April 19, 2023

Vilazodone for Depression "Viibryd made me nearly psychotic. I would wake up in a panic, unable to breathe, and had nightmares of being suffocated, waking up gasping for air. This medication made me unhinged. I am a calm, easygoing female, and I wanted to hurt people while on this med. I wouldn’t recommend this to anyone. I switched to Trintellix, and it’s been like night to day."

1 / 10
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  • Anonymous
  • December 7, 2011

Vilazodone for Depression "After trying nearly every antidepressant on the market, my doctor suggested I try Viibryd. So today was my first day of week number two. I took 10mg for the first seven days, had severe diarrhea, was extremely tired (to the point I couldn't go to work or even get off the couch), and it did nothing for my depression. Today I started the 20mg pills, have much more energy, am thinking clearly, not depressed at all, side effects did stop after the first 3 days, and have yet to come back. Overall, I'm going to stick with it. I think this might actually work."

9 / 10
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  • Boc...
  • Taken for 1 to 2 years
  • April 18, 2013

Vilazodone for Depression "I have had very good results with Viibryd, except that I think my memory is getting worse since I started this medicine. I haven't seen that mentioned anywhere as a side effect, and it may just be that I am getting older. I used to have a GREAT memory, what I called my best asset and worst fault at the same time, and I speak five languages, which is kind of a special class for an American."

10 / 10
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  • Tur...
  • Taken for 1 to 2 years
  • November 14, 2020

For Anxiety "Tried tons of different meds, none of them worked. Some, like Zoloft and Celexa, made my anxiety worse. They said it would get worse before it gets better. I don't believe that after switching meds. Once I started Viibryd, I noticed a big difference. After being on it for a couple of years, I've been great. I haven't had any anxiety. I ended up getting off of the meds to see if I could do it without Viibryd, and my anxiety came back after 6 months, so I will be starting it again."

9 / 10
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  • A00...
  • Taken for 6 months to 1 year
  • May 11, 2021

For Anxiety "I have panic disorder that has been managed for years and depression. Definitely some GAD and reactive to stress, but this is part of my job. Having taken numerous medications over 25+ years, Viibryd at 20 mg has made a huge difference. Always tried to stay away from SSRIs, emotional blunting and sexual side effects. Viibryd does not give me sexual side effects and helps manage anxiety. A very good and effective medication for me. It took 4-6 weeks to get all the positive effects."

9 / 10
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  • LoB...
  • Taken for less than 1 month
  • June 25, 2020

For Anxiety "Day 2 on vilazodone 10 mg and side effects are not nearly as bad as Prozac, which is more stimulating. I was on Lexapro, which causes weight gain. Viibryd is the best if you have intimacy issues. Nausea and diarrhea are normal. Push through this. If you survived other side effects with others, you'll be fine. We are strong. Vraylar is a good combo for mood stabilization. I'll start that once I get Viibryd in my system. Klonopin, Lorazepam, etc. aid with sleep and anxiety. SSRIs work on your serotonin, which is also in the stomach. Hence the tummy problems. Just ride it out and don't stop before your 2-week trial. If you still have issues, then consult with your doctor. Hang in there, everyone. Time is everything."

6 / 10
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  • Nat...
  • Taken for less than 1 month
  • June 6, 2020

Vilazodone for Major Depressive Disorder "My doctor started me on Viibryd after I decided I wanted to stop taking Trintellix because I couldn't deal with the side effects anymore (constant nausea, dysfunctional appetite, itchy skin). After 1.5 weeks, I've decided that Viibryd is not going to work for me either. It seemed to help with my depression, but it screwed up my sleep so much! About 3-4 hours after I'd take it, I'd be hit with this super drowsy/sleepy feeling and would start dozing off (even at work! Not ok). Some days, if I was able to, I'd just take a 2-hour nap when the sleepiness hit. But once that passed, I'd feel fine and awake again. Until I had to go to bed... The insomnia I experienced with Viibryd was no joke! I had to call in sick to work because I could not fall asleep, no matter what I did. And I knew I couldn't function at work on zero sleep. Very disappointing."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.