Comparing Trazodone vs Zofran
| Trazodone | Zofran (ondansetron) |
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| Trazodone | Zofran (ondansetron) |
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Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Zofran is used to prevent nausea and vomiting caused by cancer chemotherapy, radiotherapy, or surgery. It is approved for use in adults and children over the age of 4 and is available as tablets... View more |
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| More about Trazodone | More about Zofran (ondansetron) | ||||||||
| Ratings & Reviews | |||||||||
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Trazodone has an average rating of 6.3 out of 10 from a total of 1442 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Zofran has an average rating of 8.0 out of 10 from a total of 273 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Trazodone side effects |
View all Zofran side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Trazodone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Raldesy |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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7.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 676 drugs are known to interact with Trazodone:
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A total of 362 drugs are known to interact with Zofran:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 24, 1981 |
December 31, 1992 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.