Zofran and Vomiting: What Users Say

• Ste...
• Taken for 2 to 5 years
• October 28, 2019

For Nausea/Vomiting "I take oxycodone for chronic persistent back pain because of spinal stenosis. As a result, I frequently have nausea and vomiting, roughly 4-5 times a week. My pain management doctor always prescribes Zofran which doesn’t help in the slightest. I tell him this, but he keeps prescribing it nonetheless. He says it is safe and doesn’t make you sleepy. I say if it doesn’t work, what good is it? My GI doctor gave me Phenergan, which does help, but he tells me to go back to the pain guy to get more. I go back, tell him, yet he just gives me more Zofran. DON'T YOU JUST LOVE PHYSICIANS WHO LISTEN TO THEIR PATIENTS (sarcasm)."

• Mel...
• Taken for less than 1 month
• January 5, 2020

For Nausea/Vomiting "I've taken this medication on various occasions, and honestly, it's a lifesaver. Today, I woke up with a stomach bug. I got out of bed, drank a glass of water, and not even five minutes later, I was bent over the toilet. I laid down, and maybe half an hour later, again within two hours, I had taken six horrible, dry heaving, painful, and exhausting visits to the bathroom. Finally, I rushed to the doctor, where it happened one more time before being seen. She quickly gave me one of these, and I haven't thrown up or felt nauseous since. I've been able to keep down liquids and solids with ease. I see this medication as a great tool to help me get better faster than expected!"

• KPP...
• Taken for 10 years or more
• January 4, 2020

For Nausea/Vomiting "I’ve had a fear of vomiting for years (25+). Found out about this medication when my best friend had hyperemesis while pregnant, and it helped her stop vomiting. I asked my doctor if I could get it because I had such horrible anxiety about throwing up. I take Zofran 4-8 mg when I have bad nausea and anxiety, and it seems to help me. I did throw up once after taking it, but I think it was because I had worked myself up so much!"

• qh3...
• Taken for less than 1 month
• May 21, 2015

For Nausea/Vomiting "I was extremely hungover and was vomiting for about 14 hours non-stop before being prescribed Zofran. I know it seems silly to get medication for a hangover, but I was becoming dangerously dehydrated from binge drinking and heavy vomiting, as I was unable to keep even a sip of water down. Not even ten minutes after taking the medicine (dissolvable pills), I already felt significant relief from the nausea, and therefore the vomiting as well. A bit expensive, but completely worth it."

• RRS...
• July 8, 2017

For Gastroenteritis "22 years on massive amounts of steroids to treat my Addison's... 22 years of vomiting most days. Many hospital stays. Severe gastroenteritis. First time trying this. It's amazing! It was prescribed by a lovely doc at my last trip to the ER. Sometimes you get lucky. My eating is broken. I'm a vibrant, beautiful 42-year-old woman, and I've been reduced to a meager 100 pounds. This helps. So far. Fingers crossed."

• Ita...
• Taken for less than 1 month
• December 9, 2016

For Nausea/Vomiting "I've had central vertigo for years, but the nausea and vomiting have increased lately. My gastroenterologist prescribed Zofran 4 mg once a day. It's a miracle! I can go out and shop without vomiting in the aisles of the grocery store. I have my life back."

• Anonymous
• Taken for less than 1 month
• November 1, 2015

For Gastroenteritis "Like one of the reviews above. I went into the ER with gastroenteritis symptoms. Could not keep down anything, including water, due to nausea and heavy vomiting of anything. Was given an injection of Zofran and a prescription for the generic ondansetron and felt less nauseous. Allows me to eat better and to sleep."

• Gro...
• Taken for less than 1 month
• April 23, 2018

For Gastroenteritis "I’ve been sick with the stomach flu since last night. Ate dinner, then a couple of hours later was in the bathroom throwing up with major diarrhea. Stayed on the toilet literally all night. It was one of those “one little move and you feel like you’re going to throw up” times. Well, once morning came the puking stopped, but I was still really nauseous with dry heaves. So I called my doctor to see if there was anything I could take, and they recommended Zofran. Wow, is this a miracle drug! My nausea was gone within 10-15 minutes of taking it, and I was even able to hold down a couple of popsicles and water with it, until about an hour and a half ago when I started feeling nauseous again (the meds were wearing off, so I took another one, and within 10 minutes my nausea was gone! I even ate another popsicle and downed a little juice glass of water and didn’t throw up! If this little white, grape-flavored pill isn’t magic, then I don’t know what is!"

• Anonymous
• October 10, 2012

For Nausea/Vomiting "I can't say enough about Zofran. I was curled in a fetal position in front of the bathroom, on the floor, in a cold sweat after vomiting for the last two hours. The last bout was dry heaving. Still, the nausea was crippling me. My wife gave me one pill, and within 30 minutes, the hell I was going through broke like an ocean tide receding. I keep Zofran in the medicine cabinet now, at all times."

• swi...
• Taken for 5 to 10 years
• September 13, 2020

For Nausea/Vomiting, Chemotherapy Induced "I went through a pure nightmare during chemo for my triple negative BC in 2015. Nausea is an understatement. My oncologist told me that I was the worst patient she ever had with nausea. This is a woman who was practicing in the '70s when they still treated with mercury. I cannot tell you how many nausea medications I was prescribed. Zofran was by far the BEST medication at relieving my symptoms. Five years later I still cannot 'handle' any kind of nausea. I have an 'emergency' prescription that I have with me 24/7. I only need it maybe twice a year, but it is still the magic bullet that relieves any nausea/vomiting I may have. I HIGHLY RECOMMEND THIS MEDICATION!!!"

• Mom...
• October 16, 2015

For Nausea/Vomiting "Ever since the 5th week of my pregnancy, my morning sickness was terrible. I lost weight and couldn't keep a thing down. I could hardly get out of bed. My doctor prescribed Zofran, and it's been a huge help. Doesn't always take away the nausea feeling, but no more vomiting! Definitely recommend it."

• pra...
• March 3, 2010

For Nausea/Vomiting, Radiation Induced "I have esophageal cancer, having radiation daily and chemo weekly. This medicine is so precise about keeping the nausea and vomiting down, I can tell exactly when a dose is due: 1 every 12 hours. I am thankful this medicine is there. The side effects are very bearable (unknown concerning liver). It is very expensive, but if you have a severe issue, the money is not your main concern. If you have cancer, there are agencies that can help with the drug cost. Try AM Cancer Soc. Maybe they can help guide you. Keep your spirits up and prayers in your daily life. Take care."

• Che...
• Taken for 1 to 6 months
• December 29, 2016

For Nausea/Vomiting "I used to take Requip for restless leg syndrome, and sometimes it made me so sick I would vomit. Other nights it would be fine. One day I decided to call my PCP for a script of Zofran or Phenergan to help subside the horrible, nasty vomiting and nausea effects of Requip, and they wrote me a script of 12 4 mg Zofran swallowable tablets. It helped almost immediately (not within a minute, but 10 minutes or less), and then I decided to stop my Requip medication because it just made me sick. My RLS went away with other meds that I take, and while I still take Zofran, I enjoy it for any spur-of-the-moment 'I'M GONNA BE SICK' kind of feeling, so I always carry it with me. At a hospital visit, they gave me a dissolvable one that tasted like berries. Good med."

• Eli...
• Taken for less than 1 month
• August 22, 2019

For Nausea/Vomiting "I have taken Zofran on and off for over 10 years. I have been given it after surgery for nausea and vomiting. Also, now again for gastroparesis. Sometimes the nausea and fullness in my stomach are very uncomfortable. Because there are little to no medications or non-invasive therapies, I sometimes will use this to help settle my stomach. While it does nothing for motility, it does alleviate rough times."

• Zof...
• May 1, 2016

For Nausea/Vomiting, Chemotherapy Induced "I had a very long treatment time, 3X a week, 2 8-hour sessions with three types of chemo radiation. It was every 3rd week, Wed, Thur, and Fri. Wed/Thur were 8-hour sessions, Fri, 4 hours. I was constantly vomiting, morning, noon, and night. I took this from the get-go, but after about my 2nd session, I threw up a lot in the mornings, or if I coughed too hard even. I know it would have been SO much worse without the Zofran. I think with the amount of treatment I had, both chemo and radiation, to both my chest and to my brain that I was VERY lucky I wasn't more sick, and frankly, I'm lucky to be here at all. Thank you, Cancer Treatment Center, and of course, thank you, God!"

• sur...
• July 19, 2010

For Nausea/Vomiting, Radiation Induced "After radiation, my husband could not keep anything down. If he coughed, sneezed, brushed his teeth, or just consumed food, he would throw up. After taking this drug for three days, it has made a world of difference. It is costly, but worth the outcome."

• Sic...
• Taken for less than 1 month
• September 16, 2018

For Gastroenteritis "I'm unsure with this one. Yes, it helps the nausea a little, but I was admitted to the hospital for acute gastro - had two IV lots of this and Maxalon - lots of IV fluids - and vomited on my way out of the hospital - and every 30 minutes all night following. When I've been in the hospital and had this drug for HG (severe morning sickness), it did work, and I was asking for water and food within half an hour. I've just taken a 4 mg dissolvable and am on day 2 of the dreaded bug. Keep your fingers crossed for me xoxo."

• Sic...
• Taken for 1 to 6 months
• May 30, 2018

For Nausea/Vomiting "I have easily upsettable IBS (irritable bowel syndrome), and this has been a wonder medicine for me. Sometimes when I get up in the morning, I am so nauseous I cannot function. The dissolvable tablet leaves me feeling better within a minute. It has also worked when I had the stomach bug. It is working wonderfully now with a depression medicine that I just started taking that has a side effect of nausea and vomiting. I was seconds away from throwing up and quickly popped one of these in my mouth... back to normal within thirty seconds! Zofran is a lifesaver!"

• Gab...
• Taken for less than 1 month
• April 20, 2017

For Nausea/Vomiting "It cost me $3 for six tablets with insurance. When I was vomiting every couple of hours for a week and was prescribed Zofran, it reduced my vomiting to one or two times a day for the next two weeks as compared to every couple of hours. It is now the third week I've been sick, and the drug works within an hour for me. There were a couple of days my prescription ran out, and I started throwing up 10 times in a day again. Highly recommend."

• rit...
• Taken for less than 1 month
• April 30, 2014

For Nausea/Vomiting, Postoperative "Was given Zofran for nausea in the recovery room before going to the same-day surgery unit prior to release. Ended up with nausea, dizziness, vomiting, and shivering. After the second vomiting episode, I was given Phenergan and was able to be released in another couple of hours."

• sav...
• Taken for less than 1 month
• November 6, 2016

For Nausea/Vomiting "I was given this drug by injection in the emergency room because I had a reaction to another drug. It stopped me from vomiting. However, since immunotherapy, I have become allergic to all NSAIDs and several other drugs. One drug for a heart problem I take makes me vomit, so they gave me this drug in pill form, and well... I threw it up, and tried again, and threw it up, and this went on until I again went to the emergency room. An injection works, but the pill works only before you become nauseated. I went to another medicine, Phenergan, and that was a suppository, which worked very well."

• Reg...
• Taken for less than 1 month
• May 17, 2023

For Nausea/Vomiting "I was in the hospital. They were giving me Zofran (in IV) for nausea. After it was administered, I would have worse nausea and throw up. A nurse said sometimes Zofran can make you actually throw up. She changed to Reglan, and I finally got relief from nausea and did not vomit anymore."

• Anonymous
• June 11, 2008

For Nausea/Vomiting "I took this drug when I was pregnant. I was vomiting so much I had to be hospitalized at least 4 times and had to have in-house IV treatments. Once I took this drug, I was able to go back to work. The only problem was my insurance stopped covering the drug."

• RDe...
• September 2, 2017

For Nausea/Vomiting "I woke up this past Thursday with food poisoning. I was going to the doctor for some MRI results and told him that someone had given me leftover food from a picnic and there were a lot of mushrooms! More than one type, too. I had vomiting and nausea, so he gave me a shot of Zofran. I started to feel less nauseous immediately after the injection. I bought Gatorade on the advice of the doctor. Then I slept quite a few hours. By Friday, I was feeling 90% better. I did some research and found out I had all the symptoms of salmonella mushroom poisoning."

• mar...
• Taken for less than 1 month
• January 12, 2019

For Nausea/Vomiting "I have had severe nausea and vomiting 2 times in 2 weeks from eating seafood, so I'm guessing no more seafood. The nausea stopped after taking 2 pills. Threw up the first time, then the second one stopped it within 20 min. I'm so happy. The first time I had nausea, vomiting, and diarrhea for 5 hours, had to go to the emergency room. Once diarrhea stopped, they gave me this medication, and all stopped."