Zofran Interactions
There are 360 drugs known to interact with Zofran (ondansetron), along with 2 disease interactions. Of the total drug interactions, 127 are major, 227 are moderate, and 6 are minor.
- View all 360 medications that may interact with Zofran
- View Zofran disease interactions (2)
Most frequently checked interactions
View interaction reports for Zofran (ondansetron) and the medicines listed below.
- albuterol
- aspirin
- Ativan (lorazepam)
- baclofen
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- famotidine
- Flexeril (cyclobenzaprine)
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- melatonin
- metformin
- MiraLAX (polyethylene glycol 3350)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- propranolol
- Protonix (pantoprazole)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Zofran disease interactions
There are 2 disease interactions with Zofran (ondansetron) which include:
Report options
More about Zofran (ondansetron)
- Zofran consumer information
- Compare alternatives
- Reviews (272)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: 5HT3 receptor antagonists
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
