Zofran Drug Interactions
Currently displaying a list of 360 drugs known to interact with Zofran (ondansetron).
- 127 major drug interactions
- 227 moderate drug interactions
- 6 minor drug interactions
Medications known to interact with Zofran
Note: Showing generic names only.
- abametapir topical
- abarelix
- abiraterone
- adagrasib
- adenosine
- albuterol
- alfentanil
- alfuzosin
- almotriptan
- amiodarone
- amisulpride
- amitriptyline
- amoxapine
- anagrelide
- apalutamide
- apomorphine
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- asciminib
- asenapine
- astemizole
- atomoxetine
- azithromycin
- bedaquiline
- belzutifan
- benzgalantamine
- bepridil
- berotralstat
- bicalutamide
- bisacodyl
- bitolterol
- bosentan
- bosutinib
- brigatinib
- buprenorphine
- bupropion
- buspirone
- butorphanol
- cabozantinib
- capivasertib
- carbamazepine
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- ceritinib
- chloroquine
- chlorpromazine
- cilostazol
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clofazimine
- clomipramine
- clozapine
- codeine
- conivaptan
- crizotinib
- cyclophosphamide
- dabrafenib
- daridorexant
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- degarelix
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexfenfluramine
- dextromethorphan
- dezocine
- disopyramide
- dofetilide
- dolasetron
- donepezil
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- duloxetine
- duvelisib
- echinacea
- efavirenz
- eletriptan
- encorafenib
- entrectinib
- enzalutamide
- epirubicin
- eribulin
- erythromycin
- escitalopram
- etrasimod
- etravirine
- ezogabine
- famotidine
- fenfluramine
- fentanyl
- fexinidazole
- fingolimod
- flecainide
- fluconazole
- fluoxetine
- fluphenazine
- flutamide
- fluvoxamine
- formoterol
- foscarnet
- fostamatinib
- fostemsavir
- frovatriptan
- furazolidone
- galantamine
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glycerin
- glycerol phenylbutyrate
- goserelin
- grepafloxacin
- halofantrine
- haloperidol
- halothane
- histrelin
- hydrocodone
- hydromorphone
- hydroxychloroquine
- hydroxyzine
- ibutilide
- idarubicin
- idelalisib
- iloperidone
- imatinib
- imipramine
- indacaterol
- inotuzumab ozogamicin
- isavuconazonium
- isocarboxazid
- isoetharine
- isoproterenol
- ivabradine
- ivosidenib
- lactitol
- lactulose
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lenacapavir
- leniolisib
- lenvatinib
- letermovir
- leuprolide
- levalbuterol
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- linezolid
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lonafarnib
- lonapegsomatropin
- loperamide
- lorlatinib
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- mavacamten
- mavorixafor
- mefloquine
- meperidine
- mesoridazine
- metaproterenol
- methadone
- methotrimeprazine
- methylene blue
- metronidazole
- midostaurin
- mifepristone
- milnacipran
- mineral oil
- mirtazapine
- mitotane
- mobocertinib
- modafinil
- morphine
- morphine liposomal
- moxifloxacin
- nalbuphine
- naratriptan
- nefazodone
- nevirapine
- nilotinib
- nilutamide
- niraparib
- norfloxacin
- nortriptyline
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omaveloxolone
- oritavancin
- osilodrostat
- osimertinib
- oxaliplatin
- oxcarbazepine
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paroxetine
- pasireotide
- pazopanib
- pentamidine
- pentazocine
- perflutren
- perphenazine
- phenelzine
- phenolphthalein
- phenytoin
- pimavanserin
- pimozide
- pirbuterol
- pirtobrutinib
- pitolisant
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- ponesimod
- posaconazole
- pralsetinib
- primaquine
- probucol
- procainamide
- procarbazine
- prochlorperazine
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- protriptyline
- ranolazine
- relugolix
- remdesivir
- remifentanil
- repotrectinib
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilpivirine
- risperidone
- ritlecitinib
- ritodrine
- rivastigmine
- rizatriptan
- romidepsin
- rucaparib
- rufinamide
- salmeterol
- saquinavir
- selpercatinib
- senna
- sertraline
- sevoflurane
- sibutramine
- siponimod
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotalol
- sotorasib
- sparfloxacin
- st. john's wort
- stiripentol
- sufentanil
- sulfamethoxazole
- sumatriptan
- sunitinib
- suzetrigine
- tacrine
- tacrolimus
- tamoxifen
- tapentadol
- tebentafusp
- tecovirimat
- tedizolid
- telavancin
- telithromycin
- telotristat
- terbinafine
- terbutaline
- terfenadine
- teriflunomide
- tetrabenazine
- thalidomide
- thioridazine
- tizanidine
- toremifene
- tramadol
- tranylcypromine
- trazodone
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- triptorelin
- trofinetide
- tryptophan
- vadadustat
- valbenazine
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venlafaxine
- vilazodone
- viloxazine
- voclosporin
- vorasidenib
- voriconazole
- vortioxetine
Zofran disease interactions
There are 2 disease interactions with Zofran (ondansetron) which include:
More about Zofran (ondansetron)
- Zofran consumer information
- Check interactions
- Compare alternatives
- Reviews (272)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: 5HT3 receptor antagonists
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.