Comparing Pregabalin vs Sertraline

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Pregabalin

Sertraline

Pregabalin is used in the treatment of nerve pain and also to prevent seizures. Drowsiness or dizziness are common side effects, and it has the potential to be misused. Prescribed for Neuropathic... View more

Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Obsessive Compulsive Disorder, Panic Disorder, Major Depressive Disorder,... View more

Prescription only

Ratings & Reviews

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Drug Class

Gamma-aminobutyric acid analogs

Selective serotonin reuptake inhibitors

Side Effects

Commonly reported side effects include: infection, ataxia, blurred vision, constipation, diplopia, dizziness, drowsiness, fatigue, headache, peripheral edema, tremor, weight gain, visual field loss, accidental injury, and xerostomia.

See the full pregabalin side effects document.

Commonly reported side effects include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia.

See the full sertraline side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	50 each
Dosage	50 mg
Per Unit^*	$0.78
Cost^*	$38.90

View all pregabalin prices

Quantity	100 each
Dosage	100 mg
Per Unit^*	$0.47 - $0.48
Cost^*	$46.68 - $47.84

View all sertraline prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral capsule
Oral solution

Oral concentrate
Oral tablet

Brand Names

Lyrica, Lyrica CR Zoloft

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

6.3 hours

66 hours

CSA Schedule**

View glossary of terms.

Some potential for abuse

Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

FDA Alerts (6)

Drug Interactions

A total of 267 drugs are known to interact with pregabalin:

26 major drug interactions (142 brand and generic names)
240 moderate drug interactions (989 brand and generic names)
1 minor drug interactions (3 brand and generic names)

A total of 619 drugs are known to interact with sertraline:

141 major drug interactions (560 brand and generic names)
471 moderate drug interactions (1935 brand and generic names)
7 minor drug interactions (35 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of pregabalin such as dizziness, drowsiness,... View more

You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can... View more

Disease Interactions

First Approval Date

December 30, 2004

December 30, 1991

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer