Comparing Paroxetine vs Duloxetine
Paroxetine | Duloxetine |
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Paroxetine | Duloxetine |
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Prescription only
Paroxetine may be used in the treatment of depression or anxiety disorders. Common side effects include headaches and nausea. Taking paroxetine with other medications such as tramadol that also... View more |
Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
Related suggestions Depression
Major Depressive Disorder
Generalized Anxiety Disorder
Popular comparisons
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More about Paroxetine | More about Duloxetine | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Paroxetine has an average rating of 7.1 out of 10 from a total of 1554 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
Duloxetine has an average rating of 6.2 out of 10 from a total of 2472 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Paroxetine side effects |
View all Duloxetine side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Paroxetine prices |
View all Duloxetine prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Brisdelle, Paxil, Paxil CR | Cymbalta, Drizalma Sprinkle, Irenka | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
21 hours |
17 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 510 drugs are known to interact with Paroxetine:
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A total of 635 drugs are known to interact with Duloxetine:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 29, 1992 |
August 03, 2004 |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.