Comparing Methotrexate vs Rinvoq
| Methotrexate | Rinvoq |
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| Methotrexate | Rinvoq (upadacitinib) |
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Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Prescription only
Prescribed for Ulcerative Colitis, Rheumatoid Arthritis, Atopic Dermatitis, Psoriatic Arthritis, Ankylosing Spondylitis, Non-Radiographic Axial Spondyloarthritis, Crohn's Disease. Rinvoq may also be... View more |
Related suggestions Rheumatoid Arthritis
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| More about Methotrexate | More about Rinvoq (upadacitinib) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Methotrexate has an average rating of 6.5 out of 10 from a total of 305 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect. |
Rinvoq has an average rating of 6.2 out of 10 from a total of 111 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: methotrexate side effects in more detail. |
See also: Rinvoq side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all methotrexate prices |
View all Rinvoq prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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15 hours |
14 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 656 drugs are known to interact with methotrexate:
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A total of 510 drugs are known to interact with Rinvoq:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 07, 1953 |
August 16, 2019 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.