Comparing Lurasidone vs Sertraline

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Lurasidone	Sertraline	Enter another drug to compare

Lurasidone

Sertraline

Prescription only

Prescribed for Bipolar Disorder, Schizophrenia, Borderline Personality Disorder, Schizoaffective Disorder. Lurasidone may also be used for purposes not listed in this medication guide.

Prescription only

Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more

More about Lurasidone

More about Sertraline

Ratings & Reviews

Lurasidone has an average rating of 6.4 out of 10 from a total of 953 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect.

Sertraline has an average rating of 7.3 out of 10 from a total of 4567 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect.

View all 953 reviews

View all 4567 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Restlessness (15.3%)
Anxiety (15.0%)
Weight gain (11.5%)
Nausea (11.1%)
Depression (7.5%)
Insomnia (6.9%)
Tiredness (6.9%)

View all Lurasidone side effects

Anxiety (17.9%)
Nausea (12.2%)
Insomnia (10.7%)
Headaches (7.7%)
Tiredness (7.2%)
Sexual dysfunction (6.9%)
Depression (6.7%)

View all Sertraline side effects

Drug Class

Atypical antipsychotics

Selective serotonin reuptake inhibitors

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	40 mg
Per unit^*	$3.93
Cost^*	$117.79

View all Lurasidone prices

Quantity	50 each
Strength	100 mg
Per unit^*	$0.58
Cost^*	$28.98

View all Sertraline prices

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Dosage Forms

Oral tablet

Oral capsule
Oral concentrate
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

18 hours

66 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 632 drugs are known to interact with Lurasidone:

112 major drug interactions (432 brand and generic names)
518 moderate drug interactions (1951 brand and generic names)
2 minor drug interactions (5 brand and generic names)

A total of 673 drugs are known to interact with Sertraline:

157 major drug interactions (613 brand and generic names)
511 moderate drug interactions (2147 brand and generic names)
5 minor drug interactions (25 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Avoid consuming grapefruit or grapefruit juice during treatment with lurasidone, as it may increase... View more

Using sertraline together with alcohol may increase side effects such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

October 28, 2010

December 30, 1991

WADA Class View classifications

N/A

More Information

Patient Resources

Sertraline uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Lurasidone vs Sertraline

See also:

Rexulti

Vraylar

Caplyta

Abilify

Seroquel

Lamictal

Depakote

Zyprexa

Latuda

Risperdal

Further information

Comparing Lurasidone vs Sertraline

See also:

Further information

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