Imipramine Compared to Alternatives

For Depression: 25mg, once a day at night. For the first 7-8 weeks of taking this medication there was no positive effect on my mood, around week 3/4 my mood was noticeably worse. During the 7-8 week period I constantly felt disconnected and lacked any sort of motivation or energy to engage in any activity that involved thinking, especially social situations. I would constantly have a dry mouth and dry eyes and in addition I also had trouble urinating in the morning and when standing up I would feel light headed and dizzy for a few seconds, this was worse if I had been lying down. However, now my mood is much more stable and the side effects are gone but if I miss more than 2-3 doses then I feel incredibly low for about a week but then pick up again.

For Depression: I switched from Prozac to Imipramine after reading extensively about how successful it was before the advent of SSRI's. I have had ZERO side effects and no drowsiness on 100mg of Imipramine, while Prozac made me manic and absolutely ruined my gastrointestinal tract. I have been very happy with this medicine, best one I have taken so far for Major Depression. It is also cheap.

For Depression: I started Cymbalta over a month ago. I have been on at least six other Depression medications in the past. Before this medicine, my Depression was so bad I couldn't go to work without losing it. I was unemployed for two months to take time away to get help with Depression. I spent a week in the hospital because I was ready to kill myself and felt like I didn't have a purpose for being here. I learned a lot about myself in the hospital, it was one of the best things I could of done for myself. As of today I am a month free of Depression. Where before I couldn't go minutes without major Depression. I have energy and motivation again. I do have a decreased appetitie on this medication. I take it once in the morning and at night.

For Depression: I took Cymbalta for 1 year. It did help with my depression however, I became very lethargic and gained 25 lbs within 3 months. The weight gain scared me because I had never gained that much in such a short period of time. Also, I did have serious constipation with Cymbalta. If you can handle the wieght gain and constipation, I think Cymbalta is the medication to at least try, it does work-or it at least worked with my depression.

For Depression: Just take these reviews with a grain of salt. A lot of reviews after taking one day, couple weeks etc. you need a full three months for maximum effectiveness. Not that it takes that long to start getting relief. Side effects are common while your body adjusts. Some of them will go away. I had no troublesome side effects with Zoloft. I always have to start out gradually. Maybe even more than they say bc I’m sensitive to meds. I got big relief from depression. Panic attacks went away. OCD went away. The cons are it made me not very motivated, felt kind of numb to strong feelings. Not feeling urgency about my life. I wouldn’t take it again for years bc it blocked my clear perspective. But it was great to get me stabilized. Things that really help but can’t completely replace anti dep is fish oil, vit d, exercise, sunlight, folate like spinach , lentils really good. Also diet really helps. Get a book called the good mood diet. Best wishes

For Depression: I have been on Zoloft for more then 20 yrs. Over the last 6-8 months I have had increased side effects. Diarrhea, loss of appetite, not sleeping, sleeping too much just laying around waiting for the next trip to the bathroom. I had blood work, colonoscopy, endoscopy, you name it. Nothing! I read up on Zoloft side effects. Bingo! I started tapering off. Already...all of my symptoms are improving. It's been only three days Depression is the same.