Imipramine Alternatives Compared
| Imipramine | Bupropion | Sertraline |
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| Imipramine | Bupropion | Sertraline |
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Prescription only
Prescribed for Enuresis, Pain, Interstitial Cystitis, Depression, Primary Nocturnal Enuresis, ADHD, Irritable Bowel Syndrome, Night Terrors, Panic Disorder, Somatoform Pain Disorder. Imipramine may... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Depression
Panic Disorder
Popular comparisons
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| More about Imipramine | More about Bupropion | More about Sertraline | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Imipramine has an average rating of 7.3 out of 10 from a total of 79 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2911 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4581 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Imipramine side effects |
View all Bupropion side effects |
View all Sertraline side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Imipramine prices |
View all Bupropion prices |
View all Sertraline prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Tofranil | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Zoloft | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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20 hours |
30 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 739 drugs are known to interact with Imipramine:
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A total of 559 drugs are known to interact with Bupropion:
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A total of 673 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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April 16, 1959 |
December 30, 1985 |
December 30, 1991 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Tofranil
Tofranil is used for depression, enuresis, pain, primary nocturnal enuresis
Tofranil-PM
Tofranil-PM is used for depression, enuresis, pain, primary nocturnal enuresis
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Silenor
Silenor (doxepin) is a sleep medicine that is used to treat people who have trouble staying asleep ...
Trimipramine
Trimipramine is used for depression, irritable bowel syndrome
Nortriptyline
Nortriptyline is a tricyclic antidepressant and is used to treat symptoms of depression. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.