Comparing Ibuprofen vs Indomethacin
| Ibuprofen | Indomethacin |
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| Ibuprofen | Indomethacin |
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Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Prescription only
Indomethacin relieves inflammation and pain associated with various types of arthritis. The risk of stomach-related and cardiovascular side effects may be higher with indomethacin than that seen... View more |
Related suggestions Rheumatoid Arthritis
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| More about Ibuprofen | More about Indomethacin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ibuprofen has an average rating of 7.4 out of 10 from a total of 233 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
Indomethacin has an average rating of 7.8 out of 10 from a total of 210 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: ibuprofen side effects in more detail. |
See also: indomethacin side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all ibuprofen prices |
View all indomethacin prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | Indocin, Indocin IV, Indocin SR, Tivorbex | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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4 hours |
4.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 397 drugs are known to interact with ibuprofen:
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A total of 400 drugs are known to interact with indomethacin:
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 19, 1974 |
June 10, 1965 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.