Indomethacin Interactions
There are 419 drugs known to interact with indomethacin, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 97 are major, 305 are moderate, and 17 are minor.
- View all 419 medications that may interact with indomethacin
- View indomethacin alcohol/food interactions (2)
- View indomethacin disease interactions (11)
Most frequently checked interactions
View interaction reports for indomethacin and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Colcrys (colchicine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Ozempic (semaglutide)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Indomethacin alcohol/food interactions
There are 2 alcohol/food interactions with indomethacin.
Indomethacin disease interactions
There are 11 disease interactions with indomethacin which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- CNS effects
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
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More about indomethacin
- indomethacin consumer information
- Compare alternatives
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- Reviews (210)
- Drug images
- Latest FDA alerts (6)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
