Indomethacin and Nausea: What Users Say

• gou...
• September 6, 2014

For Gout, Acute "The 1st time I tried indomethacin, it was magic for gout. I took it during a flare-up, and half an hour later, I felt the pain dissipate like the feeling of your foot getting 'unslept' from being asleep. The side effects were horrible. I was dizzy, nauseous, had a headache, and wanted to puke. So after the 1st time, I would only take it when I was about to go to sleep. The 1st time I tried indomethacin was 7 years ago. I have flare-ups once or twice a year since then. Now though, I don't feel the side effects, but the medicine has also stopped working. Maybe I built a tolerance to it. Before, I would take 2 tablets before I went to bed, and I would wake up pain-free."

• Guy...
• October 18, 2014

For Gout, Acute "Fairly good pain-relieving medicine, it works within hours. Side effects are bad but temporary (sleepy, nauseated, felt very lethargic). Gout attack repeats, after a few days, pain shifts from one part to the other part of the foot, redness hot from toe to the sole of the foot. Doctor is going to prescribe a maintenance medicine after seeing the results of blood work."

• Vil...
• Taken for 1 to 6 months
• October 15, 2022

For Cluster Headaches "Terrible daily headaches with nausea, brain fog, pressure, and extreme fatigue. All I can do is lie on the couch all day with no energy to do anything. Truly crippled. Even though I don't feel like it's cluster, diagnosed as cluster/TAC. The first time I took a 25 mg indomethacin, I was up and building a chest of drawers within 30 mins. Absolutely unreal! Could not believe it. Still had a headache, but a 'normal' headache. Fatigue gone. Absolutely impossible to do that without this miracle med - just 25 mg as well. Have to say, some scary side effects on occasion though - shuffling - cannot walk, spaced out when I take it sometimes, and eyesight focus problems, uncoordinated occurs the day after. HAVE to take it with lansoprazole or it destroys the GI tract. Also now diagnosed with prolonged QT syndrome - which is definitely due to the tablet's effects."

• Glo...
• Taken for less than 1 month
• November 11, 2019

For Pain "I am a 58-year-old woman. My neurologist wanted to determine if the trigeminal pain I had been diagnosed with and suffered with for over six years was instead a type of trigeminal headache. He put me on indomethacin 50 mg 3x’s per day. By the first dose of indomethacin, I was very dizzy and nauseous. I had stomach pain and extreme fatigue. I took my afternoon second dose, I had all of the above symptoms but began vomiting. I could no longer sit in the recliner but listed to the side with a pillow to halfway and half sit. I had difficulty concentrating and faded in and out between dozing and wakefulness. By the third dose, I was having dry heaves and the above symptoms were worse. I felt like what it must be like to be slipped a Mickey in an alcoholic drink, even though I don’t drink, I could imagine that's what it would be like. I stumbled to my bed, where I passed out. I do not plan on ever taking another dose of this medication."

• Anonymous
• September 22, 2009

For Gout, Acute "Be careful with indomethacin. It makes me very sick, nauseous, with a feeling of dizziness. It made me pass out three times and really worried me. I did an MRI, EKG, and blood test to determine the cause of fainting, and it turned out to be the indomethacin. The lesser of two evils: gout pain or getting sick to your stomach and fainting."

• Anonymous
• September 22, 2009

For Gout, Acute "Be careful with indomethacin. It makes me very sick, nauseous, with a feeling of dizziness. It made me pass out three times and really worried me. I did an MRI, EKG, and blood test to determine the cause of fainting, and it turned out to be the indomethacin. The lesser of two evils: gout pain or getting sick to your stomach and fainting."

• AL ...
• Taken for less than 1 month
• August 3, 2018

For Gout, Acute "I am a 64-year-old male at 145 pounds. I saw a podiatrist (DPM) at 2:30 pm on day 1. My pain was at a 7. I had my 1st 50 mg capsule of indomethacin at 5 pm. By 9 pm, my pain was at a 9. I took a pain pill because I could not tolerate the pain any longer. My prescription was 3 - 50 mg capsules a day. On day 2, my pain was down to a 3, and my foot was still swollen. On day 3, my foot was better, and I took my first capsule at 6:30 am. By 9 am, I was nauseous and vomiting. I felt lightheaded and awful. I was nauseous for several hours and lightheaded most of the day, with an awful headache. I finally started feeling better 12 hours later at 9 pm. After the 5th capsule, I got sick as a dog. I stopped the medication, it was not worth it."

• Cee...
• Taken for 2 to 5 years
• July 13, 2022

For Gout, Acute "Been suffering from biannual gout attacks for the last 5-6 years. Most painful thing I’ve ever dealt with. Indomethacin is the best drug so far. Relieves pain in hours. I went from not being able to walk to being able to limp around within 3-4 hours. It gives me some stomach pain and nausea, but that’s a small price to pay to relieve gout pain."