Comparing Doxycycline vs Metronidazole Topical
Doxycycline |
Metronidazole topical |
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Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight nor in pregnant women in the last half of... more |
Prescribed for Rosacea, Bacterial Vaginitis, Perioral Dermatitis. May also be prescribed off label for Balanoposthitis. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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6.9
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6.5
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Drug Class |
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Side Effects |
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See the full doxycycline side effects document. |
See the full metronidazole topical side effects document. |
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Pricing and Coupons* Prices are without insurance |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, NicAzel Doxy, Ocudox, Oracea, Oraxyl, Targadox, Uracil, Vibra-Tabs, Vibramycin more... | MetroCream, MetroGel, MetroGel-Vaginal, MetroLotion, Noritate, Nuvessa, Rosaclear, Rosadan, Rozex, Vandazole, Vitazol more... | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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23 hours |
N/A |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 353 drugs are known to interact with doxycycline:
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A total of 12 drugs are known to interact with metronidazole topical:
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Alcohol/Food/Lifestyle Interactions |
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No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist. |
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Disease Interactions |
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First Approval Date |
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December 05, 1967 |
November 22, 1988 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Acne it’s been two months since I started using doxycycline. Guys, oh boy, it TRULY gets worse before it gets better. It took so long for me to see any improvement. Now a few parts of my face are pretty clear, but I've still got a ways to go. I think doxycycline is worth a try, but know what you’re getting into. It won’t get better in a week like I thought it would, it’s a long process.