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Medications for Perioral Dermatitis

About Perioral Dermatitis:  Perioral dermatitis is a skin disorder characterized by tiny red bumps (papules) around the mouth.

Drugs Used to Treat Perioral Dermatitis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
clindamycin B N 2 reviews
4.0

Generic name: clindamycin topical

Brand names:  Cleocin T, Clindagel, Evoclin, Clindacin P, Clinda-Derm, Clindacin PAC, ClindaReach Pledget, Clindets …show all

Drug class: topical acne agents, vaginal anti-infectives

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

metronidazole B N X 2 reviews
6.0

Generic name: metronidazole topical

Brand names:  MetroGel, MetroCream, MetroLotion, Noritate, Rozex …show all

Drug class: vaginal anti-infectives, topical anti-rosacea agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Elidel Off Label C N 3 reviews
7.0

Generic name: pimecrolimus topical

Drug class: miscellaneous topical agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

MetroGel B N X Add review Rate

Generic name: metronidazole topical

Drug class: topical anti-rosacea agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

benzoyl peroxide C N Add review Rate

Generic name: benzoyl peroxide topical

Brand names:  Acne Treatment, Benzac, Oxy-10, PanOxyl, Benzac AC Wash, Triaz, Acne-10, Benzac AC, Benzagel, BenzEFoam, Benziq Wash, Brevoxyl, Brevoxyl Creamy Wash, Clearskin, Inova, NeoBenz Micro, Peroderm 7 Wash, Persa-Gel, SoluCLENZ Rx, Acne-Clear, Alquam-X Acne Therapy Gel, Benzac W, Benzagel Wash, Benzashave, BenzEFoam Ultra, Benziq, Binora, BPO 3 Foaming Cloths, BPO 6 Foaming Cloths, BPO 9 Foaming Cloths, BP Wash, Brevoxyl Acne Wash Kit, Clearplex, Clinac BPO, Delos, Desquam-X Wash, Fostex Wash 10%, NeoBenz Micro SD, NeoBenz Micro Wash Plus Pack, Oscion, Oxy Balance, Oxy Daily Wash, Pacnex, Riax, SE BPO …show all

Drug class: topical acne agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

erythromycin Off Label B N Add review Rate

Generic name: erythromycin topical

Brand names:  Akne-Mycin, Erygel, Romycin, Emcin Clear, Ery Pads, Erythra-Derm, Theramycin Z …show all

Drug class: topical acne agents, topical antibiotics

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Protopic Off Label C N 5 reviews
6.0

Generic name: tacrolimus topical

Drug class: miscellaneous topical agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

MetroCream B N X Add review Rate

Generic name: metronidazole topical

Drug class: topical anti-rosacea agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cleocin T B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

Clindagel B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

pimecrolimus Off Label C N 5 reviews
8.0

Generic name: pimecrolimus topical

Brand name:  Elidel

Drug class: miscellaneous topical agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

tacrolimus Off Label C N 8 reviews
6.0

Generic name: tacrolimus topical

Brand name:  Protopic

Drug class: miscellaneous topical agents

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Evoclin B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

MetroLotion B N X Add review Rate

Generic name: metronidazole topical

Drug class: topical anti-rosacea agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Noritate B N X Add review
7.0

Generic name: metronidazole topical

Drug class: topical anti-rosacea agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Acne Treatment C N Add review Rate

Generic name: benzoyl peroxide topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

Clindacin P B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents, vaginal anti-infectives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Rozex B N X Add review Rate

Generic name: metronidazole topical

Drug class: topical anti-rosacea agents

For consumers: dosage, interactions, side effects

Clinda-Derm B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Clindacin PAC B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents, vaginal anti-infectives

For consumers: dosage, interactions, side effects

ClindaReach Pledget B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Clindets B N Add review Rate

Generic name: clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

Akne-Mycin Off Label B N Add review Rate

Generic name: erythromycin topical

Drug class: topical acne agents, topical antibiotics

For consumers: dosage, side effects

For professionals: Prescribing Information

Off Label: Yes

Benzac C N Add review Rate

Generic name: benzoyl peroxide topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

Oxy-10 C N Add review Rate

Generic name: benzoyl peroxide topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

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Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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